Spots Global Cancer Trial Database for CXCR4 Targeted PET Imaging in APA Preoperative Localization Diagnosis
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Trial Identification
Brief Title: CXCR4 Targeted PET Imaging in APA Preoperative Localization Diagnosis
Official Title: A Single Center Study on the Evaluation of Diagnostic Efficacy of CXCR4 Targeted PET Imaging in Primary Aldosteronism
Study ID: NCT05839483
Conditions
Interventions
Study Description
Brief Summary: The goal of this clinical trial is to evaluate the effectiveness of CXCR4 targeted PET imaging in preoperative localization diagnosis of primary aldosteronism (PA). Participants diagnosed with PA will be asked to be scanned by 68Ga-PentixaFor PET, and then underwent adrenal venous sampling (AVS). Then, the responsible adrenal adenoma will be resected by adrenalectomy, and examined with pathological section and staining. Researchers will compare the sensitivity and specificity between 68Ga-PentixaFor PET imaging and AVS in preoperative localization diagnosis of PA.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China
Contact Details
Name: Zhe Meng
Affiliation: Wuhan University
Role: PRINCIPAL_INVESTIGATOR
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