⭐️⭐️⭐️⭐️⭐️ "A total no brainer"

⭐️⭐️⭐️⭐️⭐️ "Love this, so easy."

Spots is the easy way to track your skin, mole and cancer changes.

Spots Global Cancer Trial Database for Lower-Dose Chemoradiation in Treating Patients With Early-Stage Anal Cancer, the DECREASE Study

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Lower-Dose Chemoradiation in Treating Patients With Early-Stage Anal Cancer, the DECREASE Study

Official Title: A Randomized Phase II Study De-Intensified ChemoRadiation for Early-Stage Anal Squamous Cell Carcinoma (DECREASE)

Study ID: NCT04166318

Study Description

Brief Summary: This phase II trial studies how well lower-dose chemotherapy plus radiation (chemoradiation) therapy works in comparison to standard-dose chemoradiation in treating patients with early-stage anal cancer. Drugs used in chemotherapy, such as mitomycin, fluorouracil, and capecitabine, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Radiation therapy uses high-energy x-rays to kill tumor cells and shrink tumors. Giving chemotherapy with radiation therapy may kill more tumor cells. This study may help doctors find out if lower-dose chemoradiation is as effective and has fewer side effects than standard-dose chemoradiation, which is the usual approach for treatment of this cancer type.

Detailed Description: PRIMARY OBJECTIVES: I. To determine whether de-intensified chemoradiation for early stage squamous cell carcinoma of the anal canal (SCCA) is able to maintain excellent 2-year disease control of 85% or higher while improving anorectal health-related quality of life (HRQL), compared to standard-dose chemoradiation therapy (CRT), as measured by the change in the Fecal Incontinence Quality of Life scale (FIQoL) instrument coping/behavior domain from baseline to 1 year. SECONDARY OBJECTIVES: I. To compare changes in patient-reported outcomes (as per Fecal Incontinence Severity Index \[FISI\], Patient Reported Outcomes Measurement Information System \[PROMIS\], International Index of Erectile Function \[IIEF\], Sexual Function-Vaginal Changes Questionnaire \[SVQ\], and Vaginal Assessment Scale \[VAS\]/Vulvar Assessment Scale \[VuAS\] instruments) between the experimental and control arm. II. To compare patterns of failure (local and regional relapse versus distant; in-field versus out-of-field of radiation), disease control, and overall survival between experimental and control arm. III. To correlate vaginal dilator use during radiation delivery with sexual function. IV. To measure changes in serum total testosterone from baseline to up to 12 months after radiation. V. To validate the utility of image features of inguinal and pelvic lymph nodes obtained prior to treatment as a prognostic indicator that can identify patients with early-stage anal squamous cell carcinoma for whom treatment with de-intensified chemoradiation is appropriate. VI. To determine whether an online, interactive educational tool (eContour) may improve the quality of radiation target delineation for anal cancer. VII. To determine the incidence of and predictors for cardiovascular toxicity in patients receiving fluorouracil (5-FU) or capecitabine. OUTLINE: Patients are randomized to 1 of 2 arms. ARM A (STANDARD-DOSE CHEMORADIATION): Patients undergo 28 fractions of intensity-modulated radiation therapy (IMRT). Within 24 hours, patients also receive mitomycin intravenously (IV) over 30 minutes or less on day 1 and either fluorouracil IV over 24 hours on days 1-4 and 29-32 or capecitabine orally (PO) twice daily (BID) 5 days per week (Monday - Friday) until completion of IMRT in the absence of disease progression or unacceptable toxicity. ARM B (DE-INTENSIFIED CHEMORADIATION): Patients undergo 20 or 23 fractions of IMRT. Within 24 hours, patients also receive mitomycin IV over 30 minutes or less on day 1 and either fluorouracil IV over 24 hours on days 1-4 or capecitabine PO BID 5 days per week (Monday - Friday) until completion of IMRT in the absence of disease progression or unacceptable toxicity. After completion of study treatment, patients are followed up at 6 weeks, every 3 months for years 1-2, every 6 months for year 3, then annually for years 4-5.

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

University of Alabama at Birmingham Cancer Center, Birmingham, Alabama, United States

Anchorage Associates in Radiation Medicine, Anchorage, Alaska, United States

Anchorage Radiation Therapy Center, Anchorage, Alaska, United States

Alaska Breast Care and Surgery LLC, Anchorage, Alaska, United States

Alaska Oncology and Hematology LLC, Anchorage, Alaska, United States

Alaska Women's Cancer Care, Anchorage, Alaska, United States

Anchorage Oncology Centre, Anchorage, Alaska, United States

Katmai Oncology Group, Anchorage, Alaska, United States

Providence Alaska Medical Center, Anchorage, Alaska, United States

Fairbanks Memorial Hospital, Fairbanks, Alaska, United States

Kingman Regional Medical Center, Kingman, Arizona, United States

Cancer Center at Saint Joseph's, Phoenix, Arizona, United States

Mercy Hospital Fort Smith, Fort Smith, Arkansas, United States

CHI Saint Vincent Cancer Center Hot Springs, Hot Springs, Arkansas, United States

University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

PCR Oncology, Arroyo Grande, California, United States

Providence Saint Joseph Medical Center/Disney Family Cancer Center, Burbank, California, United States

Mercy Cancer Center �� Carmichael, Carmichael, California, United States

Mercy San Juan Medical Center, Carmichael, California, United States

Mercy Cancer Center - Elk Grove, Elk Grove, California, United States

UC San Diego Moores Cancer Center, La Jolla, California, United States

UC Irvine Health/Chao Family Comprehensive Cancer Center, Orange, California, United States

Stanford Cancer Institute Palo Alto, Palo Alto, California, United States

Mercy Cancer Center - Rocklin, Rocklin, California, United States

Mercy Cancer Center - Sacramento, Sacramento, California, United States

UC San Diego Medical Center - Hillcrest, San Diego, California, United States

Pacific Central Coast Health Center-San Luis Obispo, San Luis Obispo, California, United States

Mission Hope Medical Oncology - Santa Maria, Santa Maria, California, United States

Woodland Memorial Hospital, Woodland, California, United States

Rocky Mountain Cancer Centers-Aurora, Aurora, Colorado, United States

University of Colorado Hospital, Aurora, Colorado, United States

Rocky Mountain Cancer Centers-Boulder, Boulder, Colorado, United States

Penrose-Saint Francis Healthcare, Colorado Springs, Colorado, United States

Rocky Mountain Cancer Centers-Penrose, Colorado Springs, Colorado, United States

UCHealth Memorial Hospital Central, Colorado Springs, Colorado, United States

Memorial Hospital North, Colorado Springs, Colorado, United States

Saint Francis Cancer Center, Colorado Springs, Colorado, United States

Porter Adventist Hospital, Denver, Colorado, United States

Presbyterian - Saint Lukes Medical Center - Health One, Denver, Colorado, United States

Mercy Medical Center, Durango, Colorado, United States

Southwest Oncology PC, Durango, Colorado, United States

Mountain Blue Cancer Care Center - Swedish, Englewood, Colorado, United States

Swedish Medical Center, Englewood, Colorado, United States

The Melanoma and Skin Cancer Institute, Englewood, Colorado, United States

Poudre Valley Hospital, Fort Collins, Colorado, United States

Cancer Care and Hematology-Fort Collins, Fort Collins, Colorado, United States

UCHealth Greeley Hospital, Greeley, Colorado, United States

Saint Anthony Hospital, Lakewood, Colorado, United States

Rocky Mountain Cancer Centers-Littleton, Littleton, Colorado, United States

Littleton Adventist Hospital, Littleton, Colorado, United States

Longmont United Hospital, Longmont, Colorado, United States

Rocky Mountain Cancer Centers-Longmont, Longmont, Colorado, United States

Medical Center of the Rockies, Loveland, Colorado, United States

Parker Adventist Hospital, Parker, Colorado, United States

Saint Mary Corwin Medical Center, Pueblo, Colorado, United States

Rocky Mountain Cancer Centers-Thornton, Thornton, Colorado, United States

Beebe South Coastal Health Campus, Frankford, Delaware, United States

Beebe Medical Center, Lewes, Delaware, United States

Delaware Clinical and Laboratory Physicians PA, Newark, Delaware, United States

Helen F Graham Cancer Center, Newark, Delaware, United States

Medical Oncology Hematology Consultants PA, Newark, Delaware, United States

Christiana Care Health System-Christiana Hospital, Newark, Delaware, United States

Beebe Health Campus, Rehoboth Beach, Delaware, United States

TidalHealth Nanticoke / Allen Cancer Center, Seaford, Delaware, United States

MedStar Washington Hospital Center, Washington, District of Columbia, United States

UM Sylvester Comprehensive Cancer Center at Aventura, Aventura, Florida, United States

UM Sylvester Comprehensive Cancer Center at Coral Gables, Coral Gables, Florida, United States

UM Sylvester Comprehensive Cancer Center at Deerfield Beach, Deerfield Beach, Florida, United States

University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida, United States

Miami Cancer Institute, Miami, Florida, United States

Orlando Health Cancer Institute, Orlando, Florida, United States

UM Sylvester Comprehensive Cancer Center at Plantation, Plantation, Florida, United States

Cleveland Clinic-Weston, Weston, Florida, United States

Saint Alphonsus Cancer Care Center-Boise, Boise, Idaho, United States

Saint Luke's Cancer Institute - Boise, Boise, Idaho, United States

Saint Alphonsus Cancer Care Center-Caldwell, Caldwell, Idaho, United States

Kootenai Health - Coeur d'Alene, Coeur d'Alene, Idaho, United States

Walter Knox Memorial Hospital, Emmett, Idaho, United States

Saint Luke's Cancer Institute - Fruitland, Fruitland, Idaho, United States

Idaho Urologic Institute-Meridian, Meridian, Idaho, United States

Saint Luke's Cancer Institute - Meridian, Meridian, Idaho, United States

Saint Luke's Cancer Institute - Nampa, Nampa, Idaho, United States

Saint Alphonsus Cancer Care Center-Nampa, Nampa, Idaho, United States

Kootenai Clinic Cancer Services - Post Falls, Post Falls, Idaho, United States

Kootenai Cancer Clinic, Sandpoint, Idaho, United States

Saint Luke's Cancer Institute - Twin Falls, Twin Falls, Idaho, United States

Rush - Copley Medical Center, Aurora, Illinois, United States

Illinois CancerCare-Bloomington, Bloomington, Illinois, United States

Illinois CancerCare-Canton, Canton, Illinois, United States

Memorial Hospital of Carbondale, Carbondale, Illinois, United States

SIH Cancer Institute, Carterville, Illinois, United States

Illinois CancerCare-Carthage, Carthage, Illinois, United States

Centralia Oncology Clinic, Centralia, Illinois, United States

Northwestern University, Chicago, Illinois, United States

Rush University Medical Center, Chicago, Illinois, United States

University of Illinois, Chicago, Illinois, United States

Carle on Vermilion, Danville, Illinois, United States

Cancer Care Specialists of Illinois - Decatur, Decatur, Illinois, United States

Decatur Memorial Hospital, Decatur, Illinois, United States

Illinois CancerCare-Dixon, Dixon, Illinois, United States

Carle Physician Group-Effingham, Effingham, Illinois, United States

Crossroads Cancer Center, Effingham, Illinois, United States

Illinois CancerCare-Eureka, Eureka, Illinois, United States

Illinois CancerCare-Galesburg, Galesburg, Illinois, United States

Western Illinois Cancer Treatment Center, Galesburg, Illinois, United States

Illinois CancerCare-Kewanee Clinic, Kewanee, Illinois, United States

Northwestern Medicine Lake Forest Hospital, Lake Forest, Illinois, United States

Illinois CancerCare-Macomb, Macomb, Illinois, United States

Carle Physician Group-Mattoon/Charleston, Mattoon, Illinois, United States

Loyola University Medical Center, Maywood, Illinois, United States

Good Samaritan Regional Health Center, Mount Vernon, Illinois, United States

Cancer Care Center of O'Fallon, O'Fallon, Illinois, United States

Illinois CancerCare-Ottawa Clinic, Ottawa, Illinois, United States

Illinois CancerCare-Pekin, Pekin, Illinois, United States

OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center, Pekin, Illinois, United States

Illinois CancerCare-Peoria, Peoria, Illinois, United States

OSF Saint Francis Radiation Oncology at Peoria Cancer Center, Peoria, Illinois, United States

Methodist Medical Center of Illinois, Peoria, Illinois, United States

OSF Saint Francis Medical Center, Peoria, Illinois, United States

Illinois CancerCare-Peru, Peru, Illinois, United States

Valley Radiation Oncology, Peru, Illinois, United States

Illinois CancerCare-Princeton, Princeton, Illinois, United States

Southern Illinois University School of Medicine, Springfield, Illinois, United States

Springfield Clinic, Springfield, Illinois, United States

Memorial Medical Center, Springfield, Illinois, United States

Southwest Illinois Health Services LLP, Swansea, Illinois, United States

Carle Cancer Center, Urbana, Illinois, United States

The Carle Foundation Hospital, Urbana, Illinois, United States

Illinois CancerCare - Washington, Washington, Illinois, United States

Rush-Copley Healthcare Center, Yorkville, Illinois, United States

Reid Health, Richmond, Indiana, United States

Mary Greeley Medical Center, Ames, Iowa, United States

McFarland Clinic PC - Ames, Ames, Iowa, United States

McFarland Clinic PC-Boone, Boone, Iowa, United States

Saint Anthony Regional Hospital, Carroll, Iowa, United States

Physicians' Clinic of Iowa PC, Cedar Rapids, Iowa, United States

Saint Luke's Hospital, Cedar Rapids, Iowa, United States

Medical Oncology and Hematology Associates-West Des Moines, Clive, Iowa, United States

Mercy Cancer Center-West Lakes, Clive, Iowa, United States

Jennie Edmundson Memorial Hospital, Council Bluffs, Iowa, United States

Alegent Health Mercy Hospital, Council Bluffs, Iowa, United States

Heartland Oncology and Hematology LLP, Council Bluffs, Iowa, United States

Greater Regional Medical Center, Creston, Iowa, United States

Iowa Methodist Medical Center, Des Moines, Iowa, United States

Medical Oncology and Hematology Associates-Des Moines, Des Moines, Iowa, United States

Broadlawns Medical Center, Des Moines, Iowa, United States

Mercy Medical Center - Des Moines, Des Moines, Iowa, United States

Mission Cancer and Blood - Laurel, Des Moines, Iowa, United States

Iowa Lutheran Hospital, Des Moines, Iowa, United States

McFarland Clinic PC-Trinity Cancer Center, Fort Dodge, Iowa, United States

Trinity Regional Medical Center, Fort Dodge, Iowa, United States

McFarland Clinic PC-Jefferson, Jefferson, Iowa, United States

McFarland Clinic PC-Marshalltown, Marshalltown, Iowa, United States

Methodist West Hospital, West Des Moines, Iowa, United States

Mercy Medical Center-West Lakes, West Des Moines, Iowa, United States

University of Kansas Clinical Research Center, Fairway, Kansas, United States

Central Care Cancer Center - Garden City, Garden City, Kansas, United States

Central Care Cancer Center - Great Bend, Great Bend, Kansas, United States

University of Kansas Cancer Center, Kansas City, Kansas, United States

Lawrence Memorial Hospital, Lawrence, Kansas, United States

Olathe Health Cancer Center, Olathe, Kansas, United States

University of Kansas Cancer Center-Overland Park, Overland Park, Kansas, United States

Ascension Via Christi - Pittsburg, Pittsburg, Kansas, United States

Salina Regional Health Center, Salina, Kansas, United States

University of Kansas Health System Saint Francis Campus, Topeka, Kansas, United States

University of Kansas Hospital-Westwood Cancer Center, Westwood, Kansas, United States

Flaget Memorial Hospital, Bardstown, Kentucky, United States

Commonwealth Cancer Center-Corbin, Corbin, Kentucky, United States

Saint Joseph Hospital, Lexington, Kentucky, United States

Saint Joseph Radiation Oncology Resource Center, Lexington, Kentucky, United States

Saint Joseph Hospital East, Lexington, Kentucky, United States

Saint Joseph London, London, Kentucky, United States

Jewish Hospital, Louisville, Kentucky, United States

Saints Mary and Elizabeth Hospital, Louisville, Kentucky, United States

UofL Health Medical Center Northeast, Louisville, Kentucky, United States

Jewish Hospital Medical Center South, Shepherdsville, Kentucky, United States

Ochsner Medical Center Jefferson, New Orleans, Louisiana, United States

MaineHealth Coastal Cancer Treatment Center, Bath, Maine, United States

MaineHealth/SMHC Cancer Care and Blood Disorders-Biddeford, Biddeford, Maine, United States

LincolnHealth - Miles Campus and Hospital, Damariscotta, Maine, United States

Maine Medical Center-Bramhall Campus, Portland, Maine, United States

Penobscot Bay Medical Center, Rockport, Maine, United States

MaineHealth Cancer Care Center of York County, Sanford, Maine, United States

MaineHealth/SMHC Cancer Care and Blood Disorders-Sanford, Sanford, Maine, United States

Maine Medical Center- Scarborough Campus, Scarborough, Maine, United States

Maine Medical Partners - South Portland, South Portland, Maine, United States

Greater Baltimore Medical Center, Baltimore, Maryland, United States

Boston Medical Center, Boston, Massachusetts, United States

Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States

University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, United States

Bronson Battle Creek, Battle Creek, Michigan, United States

McLaren Cancer Institute-Bay City, Bay City, Michigan, United States

University of Michigan - Brighton Center for Specialty Care, Brighton, Michigan, United States

Henry Ford Cancer Institute-Downriver, Brownstown, Michigan, United States

McLaren Cancer Institute-Clarkston, Clarkston, Michigan, United States

Henry Ford Macomb Hospital-Clinton Township, Clinton Township, Michigan, United States

Henry Ford Medical Center-Fairlane, Dearborn, Michigan, United States

Wayne State University/Karmanos Cancer Institute, Detroit, Michigan, United States

Henry Ford Hospital, Detroit, Michigan, United States

Weisberg Cancer Treatment Center, Farmington Hills, Michigan, United States

McLaren Cancer Institute-Flint, Flint, Michigan, United States

Singh and Arora Hematology Oncology PC, Flint, Michigan, United States

Helen DeVos Children's Hospital at Spectrum Health, Grand Rapids, Michigan, United States

Spectrum Health at Butterworth Campus, Grand Rapids, Michigan, United States

Trinity Health Grand Rapids Hospital, Grand Rapids, Michigan, United States

Allegiance Health, Jackson, Michigan, United States

Bronson Methodist Hospital, Kalamazoo, Michigan, United States

West Michigan Cancer Center, Kalamazoo, Michigan, United States

Borgess Medical Center, Kalamazoo, Michigan, United States

Karmanos Cancer Institute at McLaren Greater Lansing, Lansing, Michigan, United States

Mid-Michigan Physicians-Lansing, Lansing, Michigan, United States

McLaren Cancer Institute-Lapeer Region, Lapeer, Michigan, United States

McLaren Cancer Institute-Macomb, Mount Clemens, Michigan, United States

Trinity Health Muskegon Hospital, Muskegon, Michigan, United States

Lakeland Hospital Niles, Niles, Michigan, United States

Cancer and Hematology Centers of Western Michigan - Norton Shores, Norton Shores, Michigan, United States

Ascension Providence Hospitals - Novi, Novi, Michigan, United States

Henry Ford Medical Center-Columbus, Novi, Michigan, United States

McLaren Cancer Institute-Northern Michigan, Petoskey, Michigan, United States

McLaren-Port Huron, Port Huron, Michigan, United States

Spectrum Health Reed City Hospital, Reed City, Michigan, United States

Lakeland Medical Center Saint Joseph, Saint Joseph, Michigan, United States

Marie Yeager Cancer Center, Saint Joseph, Michigan, United States

Henry Ford Macomb Health Center - Shelby Township, Shelby, Michigan, United States

Ascension Providence Hospitals - Southfield, Southfield, Michigan, United States

Munson Medical Center, Traverse City, Michigan, United States

Henry Ford West Bloomfield Hospital, West Bloomfield, Michigan, United States

Metro Health Hospital, Wyoming, Michigan, United States

Riverwood Healthcare Center, Aitkin, Minnesota, United States

Sanford Joe Lueken Cancer Center, Bemidji, Minnesota, United States

Essentia Health Saint Joseph's Medical Center, Brainerd, Minnesota, United States

Fairview Ridges Hospital, Burnsville, Minnesota, United States

Minnesota Oncology - Burnsville, Burnsville, Minnesota, United States

Cambridge Medical Center, Cambridge, Minnesota, United States

Mercy Hospital, Coon Rapids, Minnesota, United States

Essentia Health - Deer River Clinic, Deer River, Minnesota, United States

Essentia Health Saint Mary's - Detroit Lakes Clinic, Detroit Lakes, Minnesota, United States

Essentia Health Cancer Center, Duluth, Minnesota, United States

Essentia Health Saint Mary's Medical Center, Duluth, Minnesota, United States

Miller-Dwan Hospital, Duluth, Minnesota, United States

Fairview Southdale Hospital, Edina, Minnesota, United States

Lake Region Healthcare Corporation-Cancer Care, Fergus Falls, Minnesota, United States

Essentia Health - Fosston, Fosston, Minnesota, United States

Unity Hospital, Fridley, Minnesota, United States

Essentia Health Hibbing Clinic, Hibbing, Minnesota, United States

Fairview Clinics and Surgery Center Maple Grove, Maple Grove, Minnesota, United States

Minnesota Oncology Hematology PA-Maplewood, Maplewood, Minnesota, United States

Saint John's Hospital - Healtheast, Maplewood, Minnesota, United States

Abbott-Northwestern Hospital, Minneapolis, Minnesota, United States

Hennepin County Medical Center, Minneapolis, Minnesota, United States

Health Partners Inc, Minneapolis, Minnesota, United States

Monticello Cancer Center, Monticello, Minnesota, United States

New Ulm Medical Center, New Ulm, Minnesota, United States

Essentia Health - Park Rapids, Park Rapids, Minnesota, United States

Fairview Northland Medical Center, Princeton, Minnesota, United States

North Memorial Medical Health Center, Robbinsdale, Minnesota, United States

Park Nicollet Clinic - Saint Louis Park, Saint Louis Park, Minnesota, United States

Regions Hospital, Saint Paul, Minnesota, United States

United Hospital, Saint Paul, Minnesota, United States

Essentia Health Sandstone, Sandstone, Minnesota, United States

Saint Francis Regional Medical Center, Shakopee, Minnesota, United States

Lakeview Hospital, Stillwater, Minnesota, United States

Sanford Thief River Falls Medical Center, Thief River Falls, Minnesota, United States

Essentia Health Virginia Clinic, Virginia, Minnesota, United States

Ridgeview Medical Center, Waconia, Minnesota, United States

Rice Memorial Hospital, Willmar, Minnesota, United States

Minnesota Oncology Hematology PA-Woodbury, Woodbury, Minnesota, United States

Sanford Cancer Center Worthington, Worthington, Minnesota, United States

Fairview Lakes Medical Center, Wyoming, Minnesota, United States

Saint Louis Cancer and Breast Institute-Ballwin, Ballwin, Missouri, United States

Central Care Cancer Center - Bolivar, Bolivar, Missouri, United States

Parkland Health Center-Bonne Terre, Bonne Terre, Missouri, United States

Cox Cancer Center Branson, Branson, Missouri, United States

Saint Francis Medical Center, Cape Girardeau, Missouri, United States

Southeast Cancer Center, Cape Girardeau, Missouri, United States

Siteman Cancer Center at West County Hospital, Creve Coeur, Missouri, United States

Parkland Health Center - Farmington, Farmington, Missouri, United States

Capital Region Southwest Campus, Jefferson City, Missouri, United States

Freeman Health System, Joplin, Missouri, United States

Mercy Hospital Joplin, Joplin, Missouri, United States

University of Kansas Cancer Center - North, Kansas City, Missouri, United States

University of Kansas Cancer Center - Lee's Summit, Lee's Summit, Missouri, United States

University of Kansas Cancer Center at North Kansas City Hospital, North Kansas City, Missouri, United States

Delbert Day Cancer Institute at PCRMC, Rolla, Missouri, United States

Mercy Clinic-Rolla-Cancer and Hematology, Rolla, Missouri, United States

Heartland Regional Medical Center, Saint Joseph, Missouri, United States

Saint Louis Cancer and Breast Institute-South City, Saint Louis, Missouri, United States

Washington University School of Medicine, Saint Louis, Missouri, United States

Mercy Hospital South, Saint Louis, Missouri, United States

Siteman Cancer Center-South County, Saint Louis, Missouri, United States

Missouri Baptist Medical Center, Saint Louis, Missouri, United States

Siteman Cancer Center at Christian Hospital, Saint Louis, Missouri, United States

Mercy Hospital Saint Louis, Saint Louis, Missouri, United States

Siteman Cancer Center at Saint Peters Hospital, Saint Peters, Missouri, United States

Sainte Genevieve County Memorial Hospital, Sainte Genevieve, Missouri, United States

Mercy Hospital Springfield, Springfield, Missouri, United States

CoxHealth South Hospital, Springfield, Missouri, United States

Missouri Baptist Sullivan Hospital, Sullivan, Missouri, United States

Missouri Baptist Outpatient Center-Sunset Hills, Sunset Hills, Missouri, United States

Mercy Hospital Washington, Washington, Missouri, United States

Community Hospital of Anaconda, Anaconda, Montana, United States

Billings Clinic Cancer Center, Billings, Montana, United States

Bozeman Deaconess Hospital, Bozeman, Montana, United States

Benefis Healthcare- Sletten Cancer Institute, Great Falls, Montana, United States

Great Falls Clinic, Great Falls, Montana, United States

Kalispell Regional Medical Center, Kalispell, Montana, United States

Saint Patrick Hospital - Community Hospital, Missoula, Montana, United States

Community Medical Hospital, Missoula, Montana, United States

CHI Health Saint Francis, Grand Island, Nebraska, United States

CHI Health Good Samaritan, Kearney, Nebraska, United States

Saint Elizabeth Regional Medical Center, Lincoln, Nebraska, United States

Nebraska Cancer Specialists/Oncology Hematology West PC - MECC, Omaha, Nebraska, United States

Nebraska Methodist Hospital, Omaha, Nebraska, United States

Oncology Associates PC, Omaha, Nebraska, United States

Alegent Health Immanuel Medical Center, Omaha, Nebraska, United States

Alegent Health Bergan Mercy Medical Center, Omaha, Nebraska, United States

Alegent Health Lakeside Hospital, Omaha, Nebraska, United States

Creighton University Medical Center, Omaha, Nebraska, United States

Midlands Community Hospital, Papillion, Nebraska, United States

Carson Tahoe Regional Medical Center, Carson City, Nevada, United States

Cancer and Blood Specialists-Henderson, Henderson, Nevada, United States

Comprehensive Cancer Centers of Nevada - Henderson, Henderson, Nevada, United States

Comprehensive Cancer Centers of Nevada-Horizon Ridge, Henderson, Nevada, United States

Las Vegas Cancer Center-Henderson, Henderson, Nevada, United States

OptumCare Cancer Care at Seven Hills, Henderson, Nevada, United States

Comprehensive Cancer Centers of Nevada-Southeast Henderson, Henderson, Nevada, United States

GenesisCare USA - Henderson, Henderson, Nevada, United States

Las Vegas Urology - Green Valley, Henderson, Nevada, United States

Las Vegas Urology - Pebble, Henderson, Nevada, United States

Urology Specialists of Nevada - Green Valley, Henderson, Nevada, United States

Las Vegas Urology - Pecos, Las Vegas, Nevada, United States

Desert West Surgery, Las Vegas, Nevada, United States

OptumCare Cancer Care at Charleston, Las Vegas, Nevada, United States

University Medical Center of Southern Nevada, Las Vegas, Nevada, United States

Hope Cancer Care of Nevada, Las Vegas, Nevada, United States

Cancer and Blood Specialists-Shadow, Las Vegas, Nevada, United States

Radiation Oncology Centers of Nevada Central, Las Vegas, Nevada, United States

Urology Specialists of Nevada - Central, Las Vegas, Nevada, United States

GenesisCare USA - Las Vegas, Las Vegas, Nevada, United States

HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway, Las Vegas, Nevada, United States

Sunrise Hospital and Medical Center, Las Vegas, Nevada, United States

HealthCare Partners Medical Group Oncology/Hematology-San Martin, Las Vegas, Nevada, United States

Las Vegas Prostate Cancer Center, Las Vegas, Nevada, United States

Las Vegas Urology - Sunset, Las Vegas, Nevada, United States

Urology Specialists of Nevada - Southwest, Las Vegas, Nevada, United States

Radiation Oncology Centers of Nevada Southeast, Las Vegas, Nevada, United States

Ann M Wierman MD LTD, Las Vegas, Nevada, United States

Cancer and Blood Specialists-Tenaya, Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada - Northwest, Las Vegas, Nevada, United States

GenesisCare USA - Vegas Tenaya, Las Vegas, Nevada, United States

HealthCare Partners Medical Group Oncology/Hematology-Tenaya, Las Vegas, Nevada, United States

Las Vegas Urology - Cathedral Rock, Las Vegas, Nevada, United States

Las Vegas Urology - Smoke Ranch, Las Vegas, Nevada, United States

OptumCare Cancer Care at MountainView, Las Vegas, Nevada, United States

Urology Specialists of Nevada - Northwest, Las Vegas, Nevada, United States

Alliance for Childhood Diseases/Cure 4 the Kids Foundation, Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada - Town Center, Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada-Summerlin, Las Vegas, Nevada, United States

Summerlin Hospital Medical Center, Las Vegas, Nevada, United States

Las Vegas Cancer Center-Medical Center, Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada, United States

GenesisCare USA - Fort Apache, Las Vegas, Nevada, United States

OptumCare Cancer Care at Fort Apache, Las Vegas, Nevada, United States

HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills, Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada - Central Valley, Las Vegas, Nevada, United States

University Cancer Center, Las Vegas, Nevada, United States

Hope Cancer Care of Nevada-Pahrump, Pahrump, Nevada, United States

Renown Regional Medical Center, Reno, Nevada, United States

Saint Mary's Regional Medical Center, Reno, Nevada, United States

Radiation Oncology Associates, Reno, Nevada, United States

Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center, Lebanon, New Hampshire, United States

Memorial Sloan Kettering Basking Ridge, Basking Ridge, New Jersey, United States

Cooper Hospital University Medical Center, Camden, New Jersey, United States

Monmouth Medical Center, Long Branch, New Jersey, United States

Memorial Sloan Kettering Monmouth, Middletown, New Jersey, United States

Memorial Sloan Kettering Bergen, Montvale, New Jersey, United States

Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, United States

Rutgers New Jersey Medical School, Newark, New Jersey, United States

Community Medical Center, Toms River, New Jersey, United States

MD Anderson Cancer Center at Cooper-Voorhees, Voorhees, New Jersey, United States

Lovelace Medical Center-Saint Joseph Square, Albuquerque, New Mexico, United States

University of New Mexico Cancer Center, Albuquerque, New Mexico, United States

Lovelace Radiation Oncology, Albuquerque, New Mexico, United States

Lovelace Women's Hospital, Albuquerque, New Mexico, United States

Montefiore Medical Center-Einstein Campus, Bronx, New York, United States

Montefiore Medical Center-Weiler Hospital, Bronx, New York, United States

Montefiore Medical Center - Moses Campus, Bronx, New York, United States

Sands Cancer Center, Canandaigua, New York, United States

Memorial Sloan Kettering Commack, Commack, New York, United States

Mary Imogene Bassett Hospital, Cooperstown, New York, United States

Noyes Memorial Hospital/Myers Cancer Center, Dansville, New York, United States

Memorial Sloan Kettering Westchester, Harrison, New York, United States

Northwell Health/Center for Advanced Medicine, Lake Success, New York, United States

Northern Westchester Hospital, Mount Kisco, New York, United States

Mount Sinai Union Square, New York, New York, United States

Mount Sinai Chelsea, New York, New York, United States

Mount Sinai West, New York, New York, United States

Mount Sinai Hospital, New York, New York, United States

NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York, New York, United States

Memorial Sloan Kettering Cancer Center, New York, New York, United States

Wilmot Cancer Institute Radiation Oncology at Greece, Rochester, New York, United States

Highland Hospital, Rochester, New York, United States

University of Rochester, Rochester, New York, United States

Memorial Sloan Kettering Nassau, Uniondale, New York, United States

Wilmot Cancer Institute at Webster, Webster, New York, United States

Sanford Bismarck Medical Center, Bismarck, North Dakota, United States

Essentia Health Cancer Center-South University Clinic, Fargo, North Dakota, United States

Sanford South University Medical Center, Fargo, North Dakota, United States

Southpointe-Sanford Medical Center Fargo, Fargo, North Dakota, United States

Sanford Medical Center Fargo, Fargo, North Dakota, United States

Sanford Broadway Medical Center, Fargo, North Dakota, United States

Sanford Roger Maris Cancer Center, Fargo, North Dakota, United States

Essentia Health - Jamestown Clinic, Jamestown, North Dakota, United States

UHHS-Chagrin Highlands Medical Center, Beachwood, Ohio, United States

Indu and Raj Soin Medical Center, Beavercreek, Ohio, United States

Saint Elizabeth Boardman Hospital, Boardman, Ohio, United States

Dayton Physicians LLC-Miami Valley South, Centerville, Ohio, United States

Miami Valley Hospital South, Centerville, Ohio, United States

Geauga Hospital, Chardon, Ohio, United States

University of Cincinnati Cancer Center-UC Medical Center, Cincinnati, Ohio, United States

Good Samaritan Hospital - Cincinnati, Cincinnati, Ohio, United States

Oncology Hematology Care Inc-Kenwood, Cincinnati, Ohio, United States

Bethesda North Hospital, Cincinnati, Ohio, United States

TriHealth Cancer Institute-Westside, Cincinnati, Ohio, United States

TriHealth Cancer Institute-Anderson, Cincinnati, Ohio, United States

Case Western Reserve University, Cleveland, Ohio, United States

MetroHealth Medical Center, Cleveland, Ohio, United States

Cleveland Clinic Cancer Center/Fairview Hospital, Cleveland, Ohio, United States

Cleveland Clinic Foundation, Cleveland, Ohio, United States

Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States

Miami Valley Hospital, Dayton, Ohio, United States

Dayton Physician LLC-Miami Valley Hospital North, Dayton, Ohio, United States

Miami Valley Hospital North, Dayton, Ohio, United States

Mercy Cancer Center-Elyria, Elyria, Ohio, United States

Armes Family Cancer Center, Findlay, Ohio, United States

Blanchard Valley Hospital, Findlay, Ohio, United States

Orion Cancer Care, Findlay, Ohio, United States

Atrium Medical Center-Middletown Regional Hospital, Franklin, Ohio, United States

Dayton Physicians LLC-Atrium, Franklin, Ohio, United States

Dayton Physicians LLC-Wayne, Greenville, Ohio, United States

Wayne Hospital, Greenville, Ohio, United States

Cleveland Clinic Cancer Center Independence, Independence, Ohio, United States

Greater Dayton Cancer Center, Kettering, Ohio, United States

First Dayton Cancer Care, Kettering, Ohio, United States

Kettering Medical Center, Kettering, Ohio, United States

Hillcrest Hospital Cancer Center, Mayfield Heights, Ohio, United States

UH Seidman Cancer Center at Lake Health Mentor Campus, Mentor, Ohio, United States

UH Seidman Cancer Center at Southwest General Hospital, Middleburg Heights, Ohio, United States

University Hospitals Parma Medical Center, Parma, Ohio, United States

University Hospitals Portage Medical Center, Ravenna, Ohio, United States

UH Seidman Cancer Center at Firelands Regional Medical Center, Sandusky, Ohio, United States

Springfield Regional Cancer Center, Springfield, Ohio, United States

Springfield Regional Medical Center, Springfield, Ohio, United States

Dayton Physicians LLC - Troy, Troy, Ohio, United States

Upper Valley Medical Center, Troy, Ohio, United States

Saint Joseph Warren Hospital, Warren, Ohio, United States

University of Cincinnati Cancer Center-West Chester, West Chester, Ohio, United States

UH Seidman Cancer Center at Saint John Medical Center, Westlake, Ohio, United States

UHHS-Westlake Medical Center, Westlake, Ohio, United States

Saint Elizabeth Youngstown Hospital, Youngstown, Ohio, United States

Cancer Centers of Southwest Oklahoma Research, Lawton, Oklahoma, United States

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States

Mercy Hospital Oklahoma City, Oklahoma City, Oklahoma, United States

Saint Alphonsus Medical Center-Baker City, Baker City, Oregon, United States

Saint Charles Health System, Bend, Oregon, United States

Clackamas Radiation Oncology Center, Clackamas, Oregon, United States

Providence Cancer Institute Clackamas Clinic, Clackamas, Oregon, United States

Bay Area Hospital, Coos Bay, Oregon, United States

Providence Newberg Medical Center, Newberg, Oregon, United States

Saint Alphonsus Medical Center-Ontario, Ontario, Oregon, United States

Providence Portland Medical Center, Portland, Oregon, United States

Providence Saint Vincent Medical Center, Portland, Oregon, United States

Oregon Health and Science University, Portland, Oregon, United States

Saint Charles Health System-Redmond, Redmond, Oregon, United States

UPMC Altoona, Altoona, Pennsylvania, United States

UPMC-Heritage Valley Health System Beaver, Beaver, Pennsylvania, United States

Carlisle Regional Cancer Center, Carlisle, Pennsylvania, United States

Christiana Care Health System-Concord Health Center, Chadds Ford, Pennsylvania, United States

Geisinger Medical Center, Danville, Pennsylvania, United States

UPMC Hillman Cancer Center Erie, Erie, Pennsylvania, United States

UPMC Cancer Center at UPMC Horizon, Farrell, Pennsylvania, United States

UPMC Cancer Centers - Arnold Palmer Pavilion, Greensburg, Pennsylvania, United States

UPMC Pinnacle Cancer Center/Community Osteopathic Campus, Harrisburg, Pennsylvania, United States

UPMC-Johnstown/John P. Murtha Regional Cancer Center, Johnstown, Pennsylvania, United States

Geisinger Medical Oncology-Lewisburg, Lewisburg, Pennsylvania, United States

Lewistown Hospital, Lewistown, Pennsylvania, United States

UPMC Cancer Center at UPMC McKeesport, McKeesport, Pennsylvania, United States

UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion, Mechanicsburg, Pennsylvania, United States

UPMC Cancer Center - Monroeville, Monroeville, Pennsylvania, United States

UPMC Hillman Cancer Center in Coraopolis, Moon, Pennsylvania, United States

Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States

UPMC-Magee Womens Hospital, Pittsburgh, Pennsylvania, United States

UPMC-Saint Margaret, Pittsburgh, Pennsylvania, United States

UPMC-Shadyside Hospital, Pittsburgh, Pennsylvania, United States

UPMC-Passavant Hospital, Pittsburgh, Pennsylvania, United States

UPMC-Saint Clair Hospital Cancer Center, Pittsburgh, Pennsylvania, United States

Geisinger Cancer Services-Pottsville, Pottsville, Pennsylvania, United States

UPMC Cancer Center at UPMC Northwest, Seneca, Pennsylvania, United States

UPMC Uniontown Hospital Radiation Oncology, Uniontown, Pennsylvania, United States

UPMC Washington Hospital Radiation Oncology, Washington, Pennsylvania, United States

Reading Hospital, West Reading, Pennsylvania, United States

Geisinger Wyoming Valley/Henry Cancer Center, Wilkes-Barre, Pennsylvania, United States

UPMC Susquehanna, Williamsport, Pennsylvania, United States

Divine Providence Hospital, Williamsport, Pennsylvania, United States

UPMC Memorial, York, Pennsylvania, United States

AnMed Health Cancer Center, Anderson, South Carolina, United States

Gibbs Cancer Center-Gaffney, Gaffney, South Carolina, United States

Saint Francis Hospital, Greenville, South Carolina, United States

Prisma Health Cancer Institute - Faris, Greenville, South Carolina, United States

Saint Francis Cancer Center, Greenville, South Carolina, United States

Prisma Health Cancer Institute - Eastside, Greenville, South Carolina, United States

Prisma Health Cancer Institute - Greer, Greer, South Carolina, United States

Gibbs Cancer Center-Pelham, Greer, South Carolina, United States

Prisma Health Cancer Institute - Seneca, Seneca, South Carolina, United States

Spartanburg Medical Center, Spartanburg, South Carolina, United States

MGC Hematology Oncology-Union, Union, South Carolina, United States

Sanford Cancer Center Oncology Clinic, Sioux Falls, South Dakota, United States

Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota, United States

Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee, United States

Saint Joseph Regional Cancer Center, Bryan, Texas, United States

MD Anderson in The Woodlands, Conroe, Texas, United States

Parkland Memorial Hospital, Dallas, Texas, United States

UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas, United States

M D Anderson Cancer Center, Houston, Texas, United States

MD Anderson West Houston, Houston, Texas, United States

MD Anderson League City, League City, Texas, United States

MD Anderson in Sugar Land, Sugar Land, Texas, United States

Farmington Health Center, Farmington, Utah, United States

University of Utah Sugarhouse Health Center, Salt Lake City, Utah, United States

Huntsman Cancer Institute/University of Utah, Salt Lake City, Utah, United States

Central Vermont Medical Center/National Life Cancer Treatment, Berlin, Vermont, United States

University of Vermont Medical Center, Burlington, Vermont, United States

University of Vermont and State Agricultural College, Burlington, Vermont, United States

Norris Cotton Cancer Center-North, Saint Johnsbury, Vermont, United States

Providence Regional Cancer System-Aberdeen, Aberdeen, Washington, United States

Overlake Medical Center, Bellevue, Washington, United States

PeaceHealth Saint Joseph Medical Center, Bellingham, Washington, United States

Harrison HealthPartners Hematology and Oncology-Bremerton, Bremerton, Washington, United States

Harrison Medical Center, Bremerton, Washington, United States

Highline Medical Center-Main Campus, Burien, Washington, United States

Providence Regional Cancer System-Centralia, Centralia, Washington, United States

Swedish Cancer Institute-Edmonds, Edmonds, Washington, United States

Saint Elizabeth Hospital, Enumclaw, Washington, United States

Providence Regional Cancer Partnership, Everett, Washington, United States

Saint Francis Hospital, Federal Way, Washington, United States

Swedish Cancer Institute-Issaquah, Issaquah, Washington, United States

Kadlec Clinic Hematology and Oncology, Kennewick, Washington, United States

Providence Regional Cancer System-Lacey, Lacey, Washington, United States

Saint Clare Hospital, Lakewood, Washington, United States

PeaceHealth Saint John Medical Center, Longview, Washington, United States

Harrison HealthPartners Hematology and Oncology-Poulsbo, Poulsbo, Washington, United States

Valley Medical Center, Renton, Washington, United States

Pacific Gynecology Specialists, Seattle, Washington, United States

Swedish Medical Center-Ballard Campus, Seattle, Washington, United States

Swedish Medical Center-Cherry Hill, Seattle, Washington, United States

Swedish Medical Center-First Hill, Seattle, Washington, United States

PeaceHealth United General Medical Center, Sedro-Woolley, Washington, United States

Providence Regional Cancer System-Shelton, Shelton, Washington, United States

Franciscan Research Center-Northwest Medical Plaza, Tacoma, Washington, United States

Northwest Medical Specialties PLLC, Tacoma, Washington, United States

PeaceHealth Southwest Medical Center, Vancouver, Washington, United States

Providence Saint Mary Regional Cancer Center, Walla Walla, Washington, United States

North Star Lodge Cancer Center at Yakima Valley Memorial Hospital, Yakima, Washington, United States

Providence Regional Cancer System-Yelm, Yelm, Washington, United States

ThedaCare Regional Cancer Center, Appleton, Wisconsin, United States

Duluth Clinic Ashland, Ashland, Wisconsin, United States

Northwest Wisconsin Cancer Center, Ashland, Wisconsin, United States

Aurora Cancer Care-Southern Lakes VLCC, Burlington, Wisconsin, United States

Marshfield Medical Center-EC Cancer Center, Eau Claire, Wisconsin, United States

Aurora Health Care Germantown Health Center, Germantown, Wisconsin, United States

Aurora Cancer Care-Grafton, Grafton, Wisconsin, United States

Aurora BayCare Medical Center, Green Bay, Wisconsin, United States

Essentia Health-Hayward Clinic, Hayward, Wisconsin, United States

UW Cancer Center Johnson Creek, Johnson Creek, Wisconsin, United States

Aurora Cancer Care-Kenosha South, Kenosha, Wisconsin, United States

Gundersen Lutheran Medical Center, La Crosse, Wisconsin, United States

University of Wisconsin Carbone Cancer Center, Madison, Wisconsin, United States

Aurora Bay Area Medical Group-Marinette, Marinette, Wisconsin, United States

Marshfield Medical Center-Marshfield, Marshfield, Wisconsin, United States

Aurora Cancer Care-Milwaukee, Milwaukee, Wisconsin, United States

Aurora Saint Luke's Medical Center, Milwaukee, Wisconsin, United States

Medical College of Wisconsin, Milwaukee, Wisconsin, United States

Aurora Sinai Medical Center, Milwaukee, Wisconsin, United States

Marshfield Clinic-Minocqua Center, Minocqua, Wisconsin, United States

ProHealth D N Greenwald Center, Mukwonago, Wisconsin, United States

Cancer Center of Western Wisconsin, New Richmond, Wisconsin, United States

ProHealth Oconomowoc Memorial Hospital, Oconomowoc, Wisconsin, United States

Vince Lombardi Cancer Clinic - Oshkosh, Oshkosh, Wisconsin, United States

Aurora Cancer Care-Racine, Racine, Wisconsin, United States

Marshfield Medical Center-Rice Lake, Rice Lake, Wisconsin, United States

Vince Lombardi Cancer Clinic-Sheboygan, Sheboygan, Wisconsin, United States

Essentia Health-Spooner Clinic, Spooner, Wisconsin, United States

Marshfield Medical Center-River Region at Stevens Point, Stevens Point, Wisconsin, United States

Aurora Medical Center in Summit, Summit, Wisconsin, United States

Essentia Health Saint Mary's Hospital - Superior, Superior, Wisconsin, United States

Vince Lombardi Cancer Clinic-Two Rivers, Two Rivers, Wisconsin, United States

ProHealth Waukesha Memorial Hospital, Waukesha, Wisconsin, United States

UW Cancer Center at ProHealth Care, Waukesha, Wisconsin, United States

Aurora Cancer Care-Milwaukee West, Wauwatosa, Wisconsin, United States

Aurora West Allis Medical Center, West Allis, Wisconsin, United States

Diagnostic and Treatment Center, Weston, Wisconsin, United States

Marshfield Medical Center - Weston, Weston, Wisconsin, United States

Billings Clinic-Cody, Cody, Wyoming, United States

Welch Cancer Center, Sheridan, Wyoming, United States

Contact Details

Name: Jennifer A Dorth

Affiliation: ECOG-ACRIN Cancer Research Group

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

Logo

Take Control of Your Skin and Body Changes Today.

Try out Spots for free, set up only takes 2 mins.

spots app storespots app store

Join others from around the world: