Spots Global Cancer Trial Database for US Guided Erector Spinae Plane Block in Breast Cancer Surgery: Analgesia, Spread and Immunomodulation
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Trial Identification
Brief Title: US Guided Erector Spinae Plane Block in Breast Cancer Surgery: Analgesia, Spread and Immunomodulation
Official Title: Ultrasound Guided Erector Spinae Plane Block in Breast Cancer Surgery: Analgesia, Spread and Immunomodulation
Study ID: NCT04796363
Study Description
Brief Summary: Prospective interventional study
Detailed Description: The aim of the present study is to evaluate the effect of US guided unilateral ESPB using different volumes of local anaesthetics on analgesic efficacy, dermatomal spread and immunomodulation in breast cancer surgery. The primary outcome is the analgesic efficacy of the different local anaesthetic volumes of ESPB. The secondary outcomes are the dermatomal dye spread and sensory coverage, immunomodulation and complications in breast cancer surgery. Immunomodulation will be assessed by measuring Natural killer cells cytotoxicity.
Eligibility
Minimum Age: 20 Years
Eligible Ages: ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Medical Research Institute, Alexandria University, Alexandria, , Egypt
Contact Details
Name: Emad Eldin Abd El Monem Arida, Professor
Affiliation: University of Alexandria
Role: STUDY_CHAIR
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