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Spots Global Cancer Trial Database for Efficacy and Safety of Apatinib As Third Line Therapy in Patients With Advanced Ovarian Cancer

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Trial Identification

Brief Title: Efficacy and Safety of Apatinib As Third Line Therapy in Patients With Advanced Ovarian Cancer

Official Title: Efficacy and Safety of Apatinib As Third Line Therapy in Patients With Advanced Ovarian Cancer

Study ID: NCT03262545

Interventions

apatinib
Placebos

Study Description

Brief Summary: The study is to investigate the efficacy and safety of apatinib in patients with advanced ovarian cancer,who has received second-line chemotherapy and failed.

Detailed Description: Ovarian cancer is the third most common gynecological malignancy,just less than endometrial cancer and cervical cancer. Because most patients with advanced ovarian cancer can not get the ideal tumor cell reduction surgery, and multi-drug resistance often emerges after repeated chemotherapy,recurrent and metastatic ovarian cancer has become one of the major diseases that threaten women's health. There is strongly necessary to explore effective therapeutic drugs and means to improve prognosis of these patients and improve the quality of life. The study,as a double blind clinical trial ,is to investigate the efficacy and safety of apatinib in patients with advanced ovarian cancer,who has received second-line chemotherapy regimens and failed. A total of 60 patients with performance status 0-2 were enrolled in this study, and were randomly divided into two groups--one group of 40 patients receiving apatinib,and another of 20 patients receiving placebo.

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: FEMALE

Healthy Volunteers: No

Locations

Sichuan Cancer Hospital, Chendu, Sichuan, China

Contact Details

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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