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Brief Title: A Study of Oraxol in Subjects With Cutaneous Angiosarcoma
Official Title: A Phase 2 Study of Oraxol in Subjects With Cutaneous Angiosarcoma
Study ID: NCT03544567
Brief Summary: This is a non-blinded, multi-center, open-label, phase 2 study to evaluate the activity, safety, and tolerability of Oraxol in subjects with cutaneous angiosarcoma.
Detailed Description: Oraxol will be administered once daily for 3 consecutive days every week during the Treatment Period from Weeks 1 through 25. Subjects who do not have documented disease progression by the end of the Treatment Period will be eligible to receive therapy in the Treatment Extension Period; Oraxol may be administered from Week 26 onwards.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Memorial Sloan Kettering Cancer Center, New York, New York, United States
Texas Oncology, Dallas, Texas, United States
MD Anderson Cancer Center, Houston, Texas, United States
University of Washington/Fred Hutchinson Cancer Center, Seattle, Washington, United States
Prince of Wales Hospital, Shatin, Hong Kong, , Hong Kong
National Taiwan University Hospital, Taipei City, , Taiwan
Taipei Veterans General Hosptial, Taipei City, , Taiwan
University College London Hospitals NHS Foundation Trust, London, , United Kingdom
The Royal Marsden NHS Foundation Trust, London, , United Kingdom
The Christie NHS Foundation Trust, Manchester, Manchester, , United Kingdom
Name: David Cutler, MD
Affiliation: Athenex, Inc.
Role: STUDY_DIRECTOR