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Spots Global Cancer Trial Database for Fertility After Diagnosis and Management of Acquired Uterine Arteriovenous Malformation

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Trial Identification

Brief Title: Fertility After Diagnosis and Management of Acquired Uterine Arteriovenous Malformation

Official Title: Fertility After Diagnosis and Management of Acquired Uterine Arteriovenous Malformation

Study ID: NCT03656211

Interventions

Telephone interview

Study Description

Brief Summary: Uterine arteriovenous malformations (UAVM) are short circuits between systemic arterial and venous networks within the uterus. They are congenital or acquired (in the course of an endo-uterine gesture such as curettage or interventions such as caesareans or myomectomies). They can be manifested by severe metrorrhagia that can go as far as to put the patient's vital prognosis at risk. There are no recommendations for the management of UAVM since this pathology is rare and therefore series are performed with few cases. If some of these UAVM disappear spontaneously after a therapeutic abstention, when the clinical context allows it, in case of symptomatic UAVM, a selective embolization with arteriography is often carried out to postpone the hysterectomy of hemostasis. There are also more marginal management options such as Gonadotropin-Releasing Hormone agonists, methotrexate or curettage that are decided on a case by case basis depending on the symptoms and protocols of each medical team. Regarding subsequent fertility and pregnancy outcomes after conservative treatment, the number of studies is even lower.

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: FEMALE

Healthy Volunteers: No

Locations

Rennes University Hospital, Rennes cedex, , France

Contact Details

Name: Krystel NYANGOH-TIMOH

Affiliation: Rennes University Hospital

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

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