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Brief Title: Induced-T Cell Like NK Cells for B Cell Malignancies
Official Title: Induced-T Cell Like NK Cellular Immunotherapy for Refractory B Cell Malignancies
Study ID: NCT04747093
Brief Summary: Relapsed and refractory B cell malignancies show unfavorable prognosis, especially for adult patients. Now, there is no standard management for these patients. Induced-T cell-like NK cells with chimeric antigen receptor (CAR-ITNK cells) is a promising treatment option for treating B cell derived malignancy. The purpose of this study is to evaluate the efficacy and safety of CAR-ITNK cells infusions in patients with relapsed and refractory B cell malignancies.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Department of Hematology,Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China
Name: Qi-fa Liu
Affiliation: Nanfang Hospital, Southern Medical University
Role: PRINCIPAL_INVESTIGATOR