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Brief Title: A Study Evaluating CPI-1205 in Patients With B-Cell Lymphomas
Official Title: A Phase 1 Study of CPI-1205, a Small Molecule Inhibitor of EZH2, in Patients With B-Cell Lymphomas
Study ID: NCT02395601
Brief Summary: First in human, open-label, sequential dose escalation and expansion study of CPI-1205 in patients with progressive B-cell lymphomas. CPI-1205 is a small molecule inhibitor of EZH2.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Horizon Oncology Center, Lafayette, Indiana, United States
Massachusetts General Hospital, Boston, Massachusetts, United States
University of Nebraska Medical Center, Omaha, Nebraska, United States
John Theurer Cancer Center, Hackensack, New Jersey, United States
The Ohio State University James Cancer Hospital, Columbus, Ohio, United States
Sarah Cannon Research Institute, Nashville, Tennessee, United States