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Brief Title: a Clinical Research of CD19 and CD22 Targeted Prime CAR-T Cell in Relapsed/Refractory B Cell Lymphoma
Official Title: Study Evaluating Safety and Efficacy of CD19 and CD22 Targeted Prime CAR-T Cell in Patients With Relapsed/Refractory B Cell Lymphoma
Study ID: NCT04782193
Brief Summary: This is a single arm study to evaluate the efficacy and safety of CD19 and CD22 targeted prime CAR-T cells therapy for patients with relapsed/refractory B Cell Lymphoma
Detailed Description: Although the anti-CD19 CAR-T cell therapies have gained significant results in patients with relapsed and refractory B-cell hematologic malignancies. There are patients who resisted anti-CD19 CAR-T cells or with CD19 negative relapse. To make further improvement, the investigators launch such a clinical trial using CD19 and CD22 targeted prime CAR-T cells for patients with relapsed and refractory B Cell Lymphomato evaluate the efficacy and safety of CD19 and CD22 targeted prime CAR-T cell therapy.
Minimum Age: 2 Years
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
920th Hospital of Joint Logistics Support Force, Kunming, Yunnnan, China
Name: Sanbin Wang, MD
Affiliation: 920th Hospital of Joint Logistics Support Force of People's Liberation Army of China
Role: PRINCIPAL_INVESTIGATOR
Name: Cheng Qian, PhD
Affiliation: Chongqing University Cancer Hospital
Role: PRINCIPAL_INVESTIGATOR