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Brief Title: INCB050465 in Combination With Rituximab, Bendamustine and Rituximab, or Ibrutinib in Participants With Previously Treated B-Cell Lymphoma (CITADEL-112)
Official Title: A Phase 1, Open-Label, Dose-Finding Study of INCB050465 in Combination With Investigator Choice of Rituximab, Bendamustine and Rituximab, or Ibrutinib in Participants With Previously Treated B-Cell Lymphoma (CITADEL-112)
Study ID: NCT03424122
Brief Summary: The purpose of this study is to evaluate the safety and tolerability of parsaclisib when combined with rituximab, bendamustine and rituximab, or ibrutinib in participants with relapsed or refractory B-cell lymphoma.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
University of Arizona Cancer Center - Out Pt., Tucson, Arizona, United States
Indiana Blood and Marrow Transplantation, Indianapolis, Indiana, United States
Comprehensive Cancer Center of Nevada, Las Vegas, Nevada, United States
Texas Oncology, Austin, Texas, United States
Baylor Charles A. Sammons Cancer Center, Dallas, Texas, United States
Baylor College of Medicine, Houston, Texas, United States
Smith Clinic, Houston, Texas, United States
Cancer Care Centers of South Texas, San Antonio, Texas, United States
Texas Oncology San Antonio, San Antonio, Texas, United States
Asst Spedali Civili Di Brescia, Brescia, , Italy
Azienda Ospedaliera San Gerardo Di Monza, Monza, , Italy
Azienda Ospedaliera Universitaria Pisana, Pisa, , Italy
Ospedale Delle Croci - Ematologia Ravenna, Ravenna, , Italy
Hospital Germans Trias I Pujol, Badalona, , Spain
Hospital General Universitari Vall D Hebron, Barcelona, , Spain
Hospital Clinic I Provincial, Barcelona, , Spain
Fundacion Jimenez Diaz University Hospital, Madrid, , Spain
Hospital Universitario Hm Sanchinarro, Madrid, , Spain
Hospital Clinico Universitario de Salamanca, Salamanca, , Spain
Hospital Universitario Virgen Del Rocio, Sevilla, , Spain
Hospital Universitario Y Politecnic La Fe, Valencia, , Spain
Name: Peter Langmuir, MD
Affiliation: Incyte Corporation
Role: STUDY_DIRECTOR