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Brief Title: Combination Study of Urelumab and Rituximab in Patients With B-cell Non-Hodgkins Lymphoma
Official Title: A Phase 1b, Open-label, Multicenter Study of Urelumab (BMS-663513) in Combination With Rituximab in Subjects With Relapsed/Refractory B-cell Malignancies
Study ID: NCT01775631
Brief Summary: The purpose of the study is to determine the safety, tolerability and maximum tolerated dose of Urelumab in combination with Rituximab in patients with B-cell Non-Hodgkins Lymphoma
Detailed Description: Intervention model: Dose Escalation (part 1) of study= Sequential Design; Dose Expansion (part 2) of study= Parallel Design
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Ucla Department Of Medicine, Los Angeles, California, United States
Stanford University Medical Center, Stanford, California, United States
Mount Sinai Comprehensive Cancer Center, Miami Beach, Florida, United States
University Of Miami Sylvester Comprehensive Cancer Center, Miami, Florida, United States
University Of Iowa Hospitals And Clinics, Iowa City, Iowa, United States
Dana Faber Cancer Institute, Boston, Massachusetts, United States
University Of Michigan Health System, Ann Arbor, Michigan, United States
Karmanos Cancer Institute, Detroit, Michigan, United States
John Theurer Cancer Center, Hackensack, New Jersey, United States
Memorial Sloan Kettering Cancer Center, New York, New York, United States
Levine Cancer Institute, Charlotte, North Carolina, United States
Providence Cancer Center Oncology And Hematology Care- Eastside, Portland, Oregon, United States
Hospital Of The University Of Pennsylvania, Philadelphia, Pennsylvania, United States
The University Of Texas Md Anderson Cancer Center, Houston, Texas, United States
University Of Virginia School Of Medicine, Charlottesville, Virginia, United States
Name: Bristol-Myers Squibb
Affiliation: Bristol-Myers Squibb
Role: STUDY_DIRECTOR