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Brief Title: Long-term Extension Study of Zanubrutinib (BGB-3111) Regimens in Participants With B-cell Malignancies
Official Title: An Open-label, Multi-center, Long-term Extension Study of Zanubrutinib (BGB-3111) Regimens in Patients With B-cell Malignancies
Study ID: NCT04170283
Brief Summary: The purpose of this study is to evaluate the long-term safety of zanubrutinib regimens in participants with B-cell malignancies who participated in a BeiGene parent study for zanubrutinib.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Carti Cancer Center, Little Rock, Arkansas, United States
Rocky Mountain Cancer Centers Centennial, Centennial, Colorado, United States
Florida Cancer Specialists Fort Myers, Fort Myers, Florida, United States
Scri Florida Cancer Specialists North, Saint Petersburg, Florida, United States
Dana Farber Cancer Institute, Boston, Massachusetts, United States
Forrest General Hospital Cancer Center, Hattiesburg, Mississippi, United States
University of Nebraska Medical Center, Omaha, Nebraska, United States
Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada, United States
Summit Medical Group, Florham Park, New Jersey, United States
Atlantic Health System, Morristown, New Jersey, United States
Clinical Research Alliance, Inc, Westbury, New York, United States
Duke University Hospital, Durham, North Carolina, United States
Oncology Associates of Oregon Willamette Valley Cancer Center, Eugene, Oregon, United States
Oregon Health and Science University, Portland, Oregon, United States
Scri Tennessee Oncology Chattanooga, Chattanooga, Tennessee, United States
Tennessee Oncology, Nashville, Tennessee, United States
Texas Oncology Fort Worth Cancer Center, Fort Worth, Texas, United States
The University of Texas Md Anderson Cancer Center, Houston, Texas, United States
Texas Oncology San Antonio Medical Center Usor, San Antonio, Texas, United States
Oncology and Hematology Associates of Southwest Virginia, Inc, Roanoke, Virginia, United States
University of Washington Seattle Cancer Alliance, Seattle, Washington, United States
Medical Oncology Associates, Spokane, Washington, United States
Peking University Third Hospital, Beijing, Beijing, China
Peking University Peoples Hospital, Beijing, Beijing, China
Beijing Cancer Hospital, Beijing, Beijing, China
Peking Union Medical College Hospital, Beijing, Beijing, China
Fujian Medical University Union Hospital, Fuzhou, Fujian, China
Quanzhou First Affliated Hospital of Fujian Medical University, Quanzhou, Fujian, China
Guangdong Provincial Peoples Hospital, Guangzhou, Guangdong, China
Nanfang Hospital of Southern Medical University, Guangzhou, Guangdong, China
Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, China
Henan Cancer Hospital, Zhengzhou, Henan, China
Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
Tongji Hospital of Tongji Medical College Huazhong University of Science and Technology, Wuhan, Hubei, China
Jiangsu Province Hospital, Nanjing, Jiangsu, China
The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China
The First Hospital of Jilin University, Changchun, Jilin, China
Shengjing Hospital of China Medical University, Shenyang, Liaoning, China
Fudan University Shanghai Cancer Center, Shanghai, Shanghai, China
Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, Shanghai, China
West China Hospital, Sichuan University, Chengdu, Sichuan, China
Institute of Hematology and Hospital of Blood Disease, Tianjin, Tianjin, China
Tianjin Medical University Cancer Institute and Hospital, Tianjin, Tianjin, China
The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
Zhejiang Cancer Hospital, Hangzhou, Zhejiang, China
Fakultni Nemocnice Brno, Brno, , Czechia
Fakultni Nemocnice Hradec Kralove, Hradec Kralove, , Czechia
Fakultni Nemocnice Olomouc, Olomouc, , Czechia
Fakultni Nemocnice Ostrava, Ostrava, , Czechia
University Hospital Vinohrady Hematology Department, Prague, , Czechia
Vseobecna Fakultni Nemocnice V Praze, Praha, , Czechia
Centre Hospitalier Departemental de Vendee, La Roche sur Yon, , France
Centre Hospitalier Le Mans, Le Mans, , France
Chu Tours Hopital Bretonneau, Tours, , France
General Hospital of Athens Alexandra, Athens, , Greece
Policlinico Sorsola Malpighi, Aou Di Bologna, Bologna, , Italy
Istituto Romagnolo Per Lo Studio Dei Tumori Dino Amadori Irst, Meldola, , Italy
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda, Milano, , Italy
Universita Degli Studi Di Modena Azienda Ospedaliere Policlinco, Modena, , Italy
Aou Maggiore Della Carita, Novara, , Italy
Unita Di Ematologia, Dipartimento Di Ematologia Ed Oncologia, Ravenna, , Italy
Fondazione Policlinico Universitario Agostino Gemelli, Roma, , Italy
Azienda Ospedaliera S Maria Di Terni, Terni, , Italy
Azienda Ospedaliera Citta Della Salute E Della Scienza Di Torino, Torino, , Italy
Aou Santa Maria Della Misericordia Di Udine, Udine, , Italy
Inje University Busan Paik Hospital, Busan, Busan Gwang'yeogsi, Korea, Republic of
Dong A University Hospital, Busan, Busan Gwang'yeogsi, Korea, Republic of
National Cancer Center, Goyangsi, Gyeonggido, Korea, Republic of
Severance Hospital Yonsei University Health System, Seoul, Seoul Teugbyeolsi, Korea, Republic of
Samsung Medical Center Hematology Oncology, Seoul, Seoul Teugbyeolsi, Korea, Republic of
Amsterdam Umc Amc, Amsterdam, , Netherlands
Albert Schweitzer Ziekenhuis, Nijmegen, , Netherlands
Universitair Medisch Centrum Utrecht, Utrecht, , Netherlands
Interhem Opieka Szpitalna, Bialystok, , Poland
Szpital Specjalist W Brzozowie,Podkarpacki Osrodek Onkologiczny, Brzozow, , Poland
Szpital Uniwersytecki Nr Im Dr Jana Biziela, Bydgoszcz, , Poland
Samodzielny Publiczny Zaklad Opieki Zdrowotnej Zespol Szpitali Miejskich, Chorzow, , Poland
Uniwersyteckie Centrum Kliniczne, Gdansk, , Poland
Copernicus Podmiot Leczniczy Sp Z Oo Wojewodzkie Centrum Onkologii, Gdask, , Poland
Malopolskie Centrum Medyczne Sc, Krakow, , Poland
Wielospecjalistyczne Centrum Onkologii I Traumatologii Im M Kopernika W Lodzi, Lodz, , Poland
Centrum Medyczne Pratia Poznan, Skorzewo Poznan, , Poland
Hospital de La Santa Creu I Sant Pau, Barcelona, , Spain
Hospital Universitario Vall Dhebron, Barcelona, , Spain
Ico Hug Trias I Pujol, Barcelona, , Spain
Hospital Clinic de Barcelona, Barcelona, , Spain
Ico Girona, Girona, , Spain
Hospital Universitario Ramon Y Cajal, Madrid, , Spain
Hospital Universitario de Salamanca, Salamanca, , Spain
Hospital Universitario de Toledo, Toledo, , Spain
Hospital Universitari I Politecnic La Fe, Valencia, , Spain
Skanes Universitetssjukhus I Lund, Lund, , Sweden
Karolinska Universitetssjukhuset Solna, Stockholm, , Sweden
Namik Kemal University, Tekirdag, , Turkey
Nhs Grampian Ppds, Aberdeen, , United Kingdom
Birmingham Heartlands Hospital, Birmingham, , United Kingdom
The Royal Bournemouth and Christchurch Hospitals Nhs Foundation, Bournemouth, , United Kingdom
Kent and Canterbury Hospital, Canterbury, , United Kingdom
Beatson West of Scotland Cancer Centre, Glasgow, , United Kingdom
The Christie Hospital, Greater Manchester, , United Kingdom
Churchill Hospital Oxford University Hospital Nhs Trust, Headington, , United Kingdom
St Jamess Institute of Oncology, Leeds, , United Kingdom
Barts Health Nhs Trust, London, , United Kingdom
University College Hospital, London, , United Kingdom
Nottingham University Hospitals Nhs Trust, Nottingham, , United Kingdom
Plymouth Hospitals Nhs Trust, Plymouth, , United Kingdom
Southampton General Hospital, Southampton, , United Kingdom
Name: Study Director
Affiliation: BeiGene
Role: STUDY_DIRECTOR