Spots Global Cancer Trial Database for Photoacoustic Endoscopy of Barrett's Esophagus

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Trial Identification

Brief Title: Photoacoustic Endoscopy of Barrett's Esophagus

Official Title: Photoacoustic Endoscopy of Barrett's Esophagus

Study ID: NCT02606292

Conditions

Barrett Esophagus

Interventions

Photoacoustic endoscopy

Endoscopic ultrasound (standard of care)

Endoscopic surgery (standard of care)

Study Description

Brief Summary: Endoscopy is an important technique in medicine to diagnose internal organs. Video endoscopy has been the most common technique providing clear, real time video images of organs' surfaces. However, this technique only images the surface and cannot effectively diagnose diseased tissues that develop in endothelial tissues. Endoscopic ultrasound (EUS) has been developed to overcome this limitation, and it is widely utilized in diagnosing GI diseases. This technique can image very deep areas of organs, up to several centimeters; however, it suffers from speckle artifacts and cannot adequately provide early diagnosis of tissue abnormalities that do not show mechanical properties that differ significantly from those of normal tissues. The investigators propose that photoacoustic endoscopy (PAE), an endoscopic embodiment of the rapidly growing photoacoustic tomography (PAT) technology, can fulfill the aforementioned need.

Detailed Description: