Spots Global Cancer Trial Database for FLASH Radiotherapy for Skin Cancer
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Trial Identification
Brief Title: FLASH Radiotherapy for Skin Cancer
Official Title: Randomized Phase II Selection Trial of FLASH Versus Conventional Radiotherapy for Patients With Localized Cutaneous Squamous Cell Carcinoma or Basal Cell Carcinoma
Study ID: NCT05724875
Study Description
Brief Summary: This is a single center randomized selected Phase II study of FLASH radiotherapy (RT) versus standard of care (SOC) radiotherapy in patients with localized Cutaneous Squamous Cell Carcinoma (cSCC) or Basal Cell Carcinoma (BCC). In summary, the aims of the study are to describe and compare the toxicity and efficacy of high dose rate radiotherapy (FLASH therapy) to SOC conventional radiotherapy (according to the standard guidelines per lesion size) through a randomized Phase II selection study in patients presenting localized cSCC or BCC requiring a radiotherapy treatment.
Detailed Description:
Eligibility
Minimum Age: 60 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Vaud, Switzerland
Contact Details
Name: Olivier Gaide, MD, PhD
Affiliation: Centre Hospitalier Universitaire Vaudois
Role: PRINCIPAL_INVESTIGATOR
Name: Jean Bourhis, MD, PhD
Affiliation: Centre Hospitalier Universitaire Vaudois
Role: STUDY_CHAIR
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