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Brief Title: A Phase II Study of Efficacy and Safety in Patients With Locally Advanced or Metastatic Basal Cell Carcinoma
Official Title: Phase II, Randomized Double-blind Study of Efficacy and Safety of Two Dose Levels of LDE225 in Patients With Locally Advanced or Metastatic Basal Cell Carcinoma
Study ID: NCT01327053
Brief Summary: This study assessed the efficacy and safety of oral treatment with two dose levels of LDE225 in patients with locally advanced or metastatic BCC.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Highlands Oncology Group, Fayetteville, Arkansas, United States
University of California at Los Angeles UCLA 3, Los Angeles, California, United States
Stanford University Medical Center Stanford Univ 2, Stanford, California, United States
University of Colorado School of Medicine UC, Aurora, Colorado, United States
Washington Hospital Center Wash Hospital, Washington, District of Columbia, United States
H Lee Moffitt Cancer Center and Research Institute Cutaneous Onc Dept, Tampa, Florida, United States
NorthwesternUniv.Med.School/Robert H. Lurie Comp.Cancer Ctr Study coordinator, Chicago, Illinois, United States
Dana Farber Cancer Institute DFCI - MA, Boston, Massachusetts, United States
Henry Ford Hospital Henry Ford, Detroit, Michigan, United States
Washington University School Of Medicine-Siteman Cancer Ctr Siteman, Saint Louis, Missouri, United States
Comprehensive Cancer Centers of Nevada CCC of Nevada- Southwest (2), Las Vegas, Nevada, United States
Hackensack University Medical Center Hackensack (SC), Hackensack, New Jersey, United States
New York University Medical Center SC-2, New York, New York, United States
Penn State University / Milton S. Hershey Medical Center Hershey Medical, Hershey, Pennsylvania, United States
University of Pittsburgh Medical Center UPMC, Pittsburgh, Pennsylvania, United States
Baylor Health Care System/Sammons Cancer Center Baylor Texas Oncology, Dallas, Texas, United States
Texas Oncology Tex Onc 3, Dallas, Texas, United States
Texas Oncology Texas Onc - Amarillo, Dallas, Texas, United States
University of Texas MD Anderson Cancer Center MD Anderson, Houston, Texas, United States
Texas Oncology Cancer Care & Research Center, Waco, Texas, United States
Texoma Cancer Center Texoma Cancer Center, Wichita Falls, Texas, United States
University of Utah / Huntsman Cancer Institute Huntsman/Univ UT, Salt Lake City, Utah, United States
Novartis Investigative Site, St Leonards, New South Wales, Australia
Novartis Investigative Site, Geelong, Victoria, Australia
Novartis Investigative Site, Bruxelles, , Belgium
Novartis Investigative Site, Wilrijk, , Belgium
Novartis Investigative Site, Waterloo, Ontario, Canada
Novartis Investigative Site, Sainte-Foy, Quebec, Canada
Novartis Investigative Site, Lyon Cedex, , France
Novartis Investigative Site, Marseille Cedex 05, , France
Novartis Investigative Site, Pierre Benite Cedex, , France
Novartis Investigative Site, Toulouse Cedex 9, , France
Novartis Investigative Site, Villejuif Cedex, , France
Novartis Investigative Site, Berlin, , Germany
Novartis Investigative Site, Essen, , Germany
Novartis Investigative Site, Freiburg, , Germany
Novartis Investigative Site, Gera, , Germany
Novartis Investigative Site, Hannover, , Germany
Novartis Investigative Site, Kiel, , Germany
Novartis Investigative Site, Mainz, , Germany
Novartis Investigative Site, Muenchen, , Germany
Novartis Investigative Site, Muenster, , Germany
Novartis Investigative Site, Stade, , Germany
Novartis Investigative Site, Athens, , Greece
Novartis Investigative Site, Budapest, , Hungary
Novartis Investigative Site, Debrecen, , Hungary
Novartis Investigative Site, Szeged, , Hungary
Novartis Investigative Site, Torino, TO, Italy
Novartis Investigative Site, Napoli, , Italy
Novartis Investigative Site, Barcelona, Catalunya, Spain
Novartis Investigative Site, Madrid, , Spain
Novartis Investigative Site, Madrid, , Spain
Novartis Investigative Site, Bern, , Switzerland
Novartis Investigative Site, Geneve, , Switzerland
Novartis Investigative Site, Zürich, , Switzerland
Novartis Investigative Site, High Heaton, Newcastle Upon Tyne, United Kingdom
Novartis Investigative Site, Yeovil, Somerset, United Kingdom
Novartis Investigative Site, Cardiff, , United Kingdom
Novartis Investigative Site, Glasgow, , United Kingdom
Novartis Investigative Site, Leicester, , United Kingdom
Novartis Investigative Site, London, , United Kingdom
Novartis Investigative Site, Manchester, , United Kingdom
Name: Novartis Pharmaceuticals
Affiliation: Novartis Pharmaceuticals
Role: STUDY_DIRECTOR