Spots Global Cancer Trial Database for Laser Therapy of Benign Thyroid Nodules

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Trial Identification

Brief Title: Laser Therapy of Benign Thyroid Nodules

Official Title: Ultrasound Guided Interstitial Laser Photocoagulation on Benign Thyroid Nodules

Study ID: NCT00150150

Conditions

Benign Solitary Solid

Cystic Thyroid Nodules

Interventions

Interstitial laser photocoagulation

Study Description

Brief Summary: Nodular goitre is common in the general population and less than 5% of the patients who undergo surgery for solitary thyroid nodules have cancer, in absence of clinical suspicion. Nodules left untreated seem to have a slight growth potential in borderline iodine-deficient areas. Interstitial laser photo-coagulation (ILP) is a procedure for local hyperthermia and photocoagulation, allowing minimally invasive treatment of benign tumors, including thyroid nodules. The aim of these studies are to evaluate if ILP will be useful in reducing the volume of the benign thyroid nodule and thyroid function will be unaffected in euthyroid patients, and normalized in pretoxic- and toxic thyroid nodules. The investigations are listed below: 1. Randomized study of interstitial laser photocoagulation for benign solitary cold thyroid nodules - one versus two or three treatments 2. Randomized study of interstitial laser photocoagulation for benign solitary autonomous thyroid nodules - 131I versus laser ablation 3. Interstitial laser photocoagulation for benign thyroid cystadenomas. - a feasibility study.

Detailed Description: