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Spots Global Cancer Trial Database for A Study of CTX-009 in Combination With Paclitaxel in Adult Patients With Unresectable Advanced, Metastatic or Recurrent Biliary Tract Cancers (COMPANION-002)

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Trial Identification

Brief Title: A Study of CTX-009 in Combination With Paclitaxel in Adult Patients With Unresectable Advanced, Metastatic or Recurrent Biliary Tract Cancers (COMPANION-002)

Official Title: A Phase 2/3 Randomized, Controlled Study of CTX-009 in Combination With Paclitaxel Versus Paclitaxel Alone in Adult Patients With Unresectable Advanced, Metastatic or Recurrent Biliary Tract Cancers Who Have Received One Prior Systemic Chemotherapy Regimen

Study ID: NCT05506943

Interventions

CTX-009
Paclitaxel

Study Description

Brief Summary: This is a multi-center, open-label, randomized, phase 2/3 trial of the bispecific antibody CTX-009 plus paclitaxel versus paclitaxel in patients with previously treated, unresectable advanced or metastatic biliary tract cancers.

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Mayo Clinic Arizona, Phoenix, Arizona, United States

University of Arizona, Tucson, Arizona, United States

University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, United States

Stanford Medicine Cancer Center, Palo Alto, California, United States

University of California San Francisco, San Francisco, California, United States

Rocky Mountain Cancer Centers, LLP, Aurora, Colorado, United States

University of Florida, Gainesville, Florida, United States

Mayo Clinic Jacksonville, Jacksonville, Florida, United States

AdventHealth Orlando, Orlando, Florida, United States

Northwestern University, Chicago, Illinois, United States

University of Chicago, Chicago, Illinois, United States

Ochsner Clinic Foundation, New Orleans, Louisiana, United States

Johns Hopkins University, Baltimore, Maryland, United States

Massachusetts General Hospital, Boston, Massachusetts, United States

Mayo Clinic Rochester, Rochester, Minnesota, United States

Washington University School of Medicine, Siteman Cancer Center, Saint Louis, Missouri, United States

Rutgers Cancer Institute, New Brunswick, New Jersey, United States

The University of New Mexico, Albuquerque, New Mexico, United States

Memorial Medical Center, Las Cruces, New Mexico, United States

Montefiore Medical Center, Bronx, New York, United States

Roswell Park, Buffalo, New York, United States

Columbia University, New York, New York, United States

Gabrail Cancer Center, Canton, Ohio, United States

Cleveland Clinic, Cleveland, Ohio, United States

University of Tennessee Medical Center, Knoxville, Tennessee, United States

SCRI Oncology Partners, Nashville, Tennessee, United States

Texas Oncology - Austin, Austin, Texas, United States

Texas Oncology - Baylor Charles A. Sammons Cancer Center, Dallas, Texas, United States

Texas Oncology - Dension, Denison, Texas, United States

The University of Texas MD Anderson Cancer Center, Houston, Texas, United States

Texas Oncology - San Antonio, San Antonio, Texas, United States

Texas Oncology - Northeast Texas, Tyler, Texas, United States

Virginia Mason Franciscan Health, Seattle, Washington, United States

Northwest Cancer Specialists, P.C., Vancouver, Washington, United States

Contact Details

Name: Minori Rosales, MD, PHD

Affiliation: Compass Therapeutics

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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