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Brief Title: Rucaparib in Combination With Nivolumab in Patients With Advanced or Metastatic Biliary Tract Cancer Following Platinum Therapy
Official Title: Phase II Multi-Center Study of PARP Inhibitor Rucaparib in Combination With Anti-PD-1 Antibody Nivolumab in Patients With Advanced or Metastatic Biliary Tract Cancer Following Platinum Therapy
Study ID: NCT03639935
Brief Summary: Investigators hypothesize that following first-line platinum based chemotherapy, rucaparib in combination with nivolumab, will improve progression-free survival and overall survival in BTC patients.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Dana-Farber Cancer Institute, Boston, Massachusetts, United States
Rogel Cancer Center, Ann Arbor, Michigan, United States
Vanderbilt University Medical Center, Nashville, Tennessee, United States
Name: Vaibhav Sahai, MBBS, MS
Affiliation: Rogel Cancer Center
Role: PRINCIPAL_INVESTIGATOR