Spots Global Cancer Trial Database for XL119 Versus 5-Fluorouracil (5-FU) Plus Leucovorin (LV) in Subjects With Advanced Biliary Tumors
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Trial Identification
Brief Title: XL119 Versus 5-Fluorouracil (5-FU) Plus Leucovorin (LV) in Subjects With Advanced Biliary Tumors
Official Title: A Phase 3 Multicenter, Open Label, Randomized Study of XL119 Versus 5-Fluorouracil (5-FU) Plus Leucovorin (LV) in Subjects With Advanced Biliary Tumors Not Amenable to Conventional Surgery
Study ID: NCT00090025
Conditions
Study Description
Brief Summary: The main purpose of this study is to determine if XL119 is more effective than the combination of 5-fluorouracil (5FU) and leucovorin (LV) in prolonging the survival of subjects with advanced biliary tumors.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, Alabama, United States
Long Beach VA Medical Center, Long Beach, California, United States
University of California, Irvine Medical Center, Orange, California, United States
Sharp Clinical Oncology Research, San Diego, California, United States
Pacific Hematology Oncology Associates, San Francisco, California, United States
Yale University School of Medicine, New Haven, Connecticut, United States
Tampa General Hospital, Tampa,, Florida, United States
Winship Cancer Institute, Emory University Hospital, Atlanta, Georgia, United States
Carle Clinic Association, Urbana, Illinois, United States
Medical Consultants, PC c/o Ball Cancer Center, Muncie, Indiana, United States
Oncology Associates, Cedar Rapids, Iowa, United States
Louisiana Oncology Associates, Lafayette, Louisiana, United States
Tufts - New England Medical Center, Boston, Massachusetts, United States
Josephine Ford Cancer Center at Henry Ford Health System, Detroit, Michigan, United States
West Michigan Cancer Center, Kalamazoo, Michigan, United States
Oncology Care Center PLLC, St. Joseph, Michigan, United States
Norris Cotton Cancer Center, Lebanon, New Hampshire, United States
Queens Hospital Center, Jamaica, New York, United States
SUNY Upstate Medical University, Syracuse, New York, United States
New York Medical College, Valhalla, New York, United States
Cancer Treatment and Research Center, Bismark, North Dakota, United States
Gabrail Cancer Center, Canton, Ohio, United States
Case Western Reserve University, Cleveland, Ohio, United States
Charleston Hematology Oncology, PA, Charleston, South Carolina, United States
The Sarah Cannon Cancer Center, Nashville, Tennessee, United States
Western Washington Oncology, Inc., Lacey, Washington, United States
University of Wisconsin Comprehensive Cancer Center, Madison, Wisconsin, United States
Universitair Ziekenhuis Gent, Ghent, , Belgium
British Columbia Cancer Agency - Vancouver Centre, Vancouver, British Columbia, Canada
London Regional Cancer Centre, London, Ontario, Canada
Ottawa Regional Cancer Centre, Ottawa, Ontario, Canada
Centre Hospitalier Universite de Montreal, Montreal, Quebec, Canada
Jewish General Hospital, Montreal, Quebec, Canada
CHU - Hospital Jean Minjoz, Besancon cedex, , France
Hospital Ambroise Pare, Boulogne Billancourt, , France
Centre Oscar Lambret, Lille cedex, , France
Institut Gustave Roussy, Villejuif Cedex, , France
Charite Berlin der Humbold Universitat, Berlin, , Germany
Heinrich-Heine-Universitat-Dusseldorf, Dusseldorf, , Germany
Allgem. Krankenhaus St. Georg, Hamburg, , Germany
Medizinische Hochschule Hannover, Hannover, , Germany
Universitätsklinikum Johannes Gutenberg, Mainz, , Germany
Technischen Universitat Munchen, Munich, , Germany
Klinikum Grosshadern der Ludwig Maximilians Universitaet, Munich, , Germany
Universitätsklinikum Tübingen, Tübingen, , Germany
Universitatsklinikum Ulm, Ulm, , Germany
Orszagos Onkologiai Intezet, Budapest, , Hungary
Centro di Riferimento Oncologico di Aviano, Aviano, , Italy
Ospidale Civile di Livorno, Livorno, , Italy
Policlinico Universitario di Udine, Udine, , Italy
Centrum Onkologii - Instytut im. Marii, Warszawa, , Poland
Cancer Research Center named after N.N. Blokhin, RAMS, Moscow, , Russian Federation
Hospital Clinic i Provincial (Oncology Department), Barcelona, , Spain
Hospital Clínico San Carlos, Madrid, , Spain
Hospital 12 de Octubre, Madrid, , Spain
Hospital Regional Universitario Carlos Haya, Malaga, , Spain
Hospital Provincial de Pontevedra, Pontevedra, , Spain
Hospital Lozano Blesa, Zaragoza, , Spain
Leicester Royal Infirmary, Leicester, England, United Kingdom
Contact Details
Name: Afshin Dowlati, MD
Affiliation: Case Western Reserve University - Cleveland
Role: STUDY_CHAIR
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