Spots Global Cancer Trial Database for Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors
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Trial Identification
Brief Title: Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors
Official Title: A Phase II Study of Ipilimumab, Cabozantinib, and Nivolumab in Rare Genitourinary Cancers (ICONIC)
Study ID: NCT03866382
Conditions
Study Description
Brief Summary: This phase II trial studies how well cabozantinib works in combination with nivolumab and ipilimumab in treating patients with rare genitourinary (GU) tumors that that has spread from where it first started (primary site) to other places in the body. Cabozantinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving cabozantinib, nivolumab, and ipilimumab may work better in treating patients with genitourinary tumors that have no treatment options compared to giving cabozantinib, nivolumab, or ipilimumab alone.
Detailed Description: PRIMARY OBJECTIVE: I. To evaluate the efficacy of cabozantinib s-malate (cabozantinib) combined with nivolumab and ipilimumab in the first or second-line (and beyond) setting for patients within each of the rare genitourinary (GU) variant histology group of interest, as measured by objective response rate (ORR). SECONDARY OBJECTIVES: I. To estimate the progression-free survival (PFS) for patients treated with cabozantinib combined with nivolumab and ipilimumab within each rare variant histology. II. To estimate the overall survival (OS) for patients treated with cabozantinib combined with nivolumab and ipilimumab within each rare variant histology. III. To estimate the clinical benefit rate (defined as complete response \[CR\] or partial response \[PR\] or stable disease \[SD\]) for patients treated with cabozantinib combined with nivolumab and ipilimumab within each rare variant histology. IV. To assess the safety of treating patients with rare variant histologies with cabozantinib combined with nivolumab and ipilimumab. V. To support tissue banking and collection of clinical follow-up data for GU tract rare histological variants. EXPLORATORY OBJECTIVES: I. To assess effects of treatment in patients with bone-only disease by bone scan. OUTLINE: Patients receive cabozantinib orally (PO), nivolumab intravenously (IV) and ipilimumab IV while on study. Patients undergo computed tomography (CT) scan, magnetic resonance imaging (MRI), positron emission tomography (PET) and bone scans throughout the study.
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
University of Alabama at Birmingham Cancer Center, Birmingham, Alabama, United States
Anchorage Associates in Radiation Medicine, Anchorage, Alaska, United States
Anchorage Radiation Therapy Center, Anchorage, Alaska, United States
Alaska Breast Care and Surgery LLC, Anchorage, Alaska, United States
Alaska Oncology and Hematology LLC, Anchorage, Alaska, United States
Alaska Women's Cancer Care, Anchorage, Alaska, United States
Anchorage Oncology Centre, Anchorage, Alaska, United States
Katmai Oncology Group, Anchorage, Alaska, United States
Providence Alaska Medical Center, Anchorage, Alaska, United States
Kingman Regional Medical Center, Kingman, Arizona, United States
Cancer Center at Saint Joseph's, Phoenix, Arizona, United States
Mayo Clinic Hospital in Arizona, Phoenix, Arizona, United States
Mayo Clinic in Arizona, Scottsdale, Arizona, United States
University of Arizona Cancer Center-Orange Grove Campus, Tucson, Arizona, United States
Banner University Medical Center - Tucson, Tucson, Arizona, United States
University of Arizona Cancer Center-North Campus, Tucson, Arizona, United States
Mercy Hospital Fort Smith, Fort Smith, Arkansas, United States
CHI Saint Vincent Cancer Center Hot Springs, Hot Springs, Arkansas, United States
Mission Hope Medical Oncology - Arroyo Grande, Arroyo Grande, California, United States
PCR Oncology, Arroyo Grande, California, United States
Providence Saint Joseph Medical Center/Disney Family Cancer Center, Burbank, California, United States
Community Cancer Institute, Clovis, California, United States
University Oncology Associates, Clovis, California, United States
Epic Care-Dublin, Dublin, California, United States
Bay Area Breast Surgeons Inc, Emeryville, California, United States
Epic Care Partners in Cancer Care, Emeryville, California, United States
Marin Cancer Care Inc, Greenbrae, California, United States
Los Angeles General Medical Center, Los Angeles, California, United States
USC / Norris Comprehensive Cancer Center, Los Angeles, California, United States
UCLA / Jonsson Comprehensive Cancer Center, Los Angeles, California, United States
Contra Costa Regional Medical Center, Martinez, California, United States
USC Norris Oncology/Hematology-Newport Beach, Newport Beach, California, United States
Alta Bates Summit Medical Center - Summit Campus, Oakland, California, United States
Bay Area Tumor Institute, Oakland, California, United States
Pacific Central Coast Health Center-San Luis Obispo, San Luis Obispo, California, United States
Mission Hope Medical Oncology - Santa Maria, Santa Maria, California, United States
Epic Care Cyberknife Center, Walnut Creek, California, United States
Penrose-Saint Francis Healthcare, Colorado Springs, Colorado, United States
Rocky Mountain Cancer Centers-Penrose, Colorado Springs, Colorado, United States
Porter Adventist Hospital, Denver, Colorado, United States
Mercy Medical Center, Durango, Colorado, United States
Southwest Oncology PC, Durango, Colorado, United States
Saint Anthony Hospital, Lakewood, Colorado, United States
Littleton Adventist Hospital, Littleton, Colorado, United States
Longmont United Hospital, Longmont, Colorado, United States
Rocky Mountain Cancer Centers-Longmont, Longmont, Colorado, United States
Parker Adventist Hospital, Parker, Colorado, United States
Saint Mary Corwin Medical Center, Pueblo, Colorado, United States
MedStar Georgetown University Hospital, Washington, District of Columbia, United States
Mount Sinai Comprehensive Cancer Center at Aventura, Aventura, Florida, United States
Holy Cross Hospital, Fort Lauderdale, Florida, United States
Mount Sinai Medical Center, Miami Beach, Florida, United States
Orlando Health Cancer Institute, Orlando, Florida, United States
Emory University Hospital Midtown, Atlanta, Georgia, United States
Emory University Hospital/Winship Cancer Institute, Atlanta, Georgia, United States
Emory Saint Joseph's Hospital, Atlanta, Georgia, United States
Emory Johns Creek Hospital, Johns Creek, Georgia, United States
Saint Alphonsus Cancer Care Center-Boise, Boise, Idaho, United States
Saint Luke's Cancer Institute - Boise, Boise, Idaho, United States
Saint Alphonsus Cancer Care Center-Caldwell, Caldwell, Idaho, United States
Kootenai Health - Coeur d'Alene, Coeur d'Alene, Idaho, United States
Walter Knox Memorial Hospital, Emmett, Idaho, United States
Saint Luke's Cancer Institute - Fruitland, Fruitland, Idaho, United States
Idaho Urologic Institute-Meridian, Meridian, Idaho, United States
Saint Luke's Cancer Institute - Meridian, Meridian, Idaho, United States
Saint Luke's Cancer Institute - Nampa, Nampa, Idaho, United States
Saint Alphonsus Cancer Care Center-Nampa, Nampa, Idaho, United States
Kootenai Clinic Cancer Services - Post Falls, Post Falls, Idaho, United States
Kootenai Cancer Clinic, Sandpoint, Idaho, United States
Saint Luke's Cancer Institute - Twin Falls, Twin Falls, Idaho, United States
Saint Anthony's Health, Alton, Illinois, United States
Rush - Copley Medical Center, Aurora, Illinois, United States
Illinois CancerCare-Bloomington, Bloomington, Illinois, United States
Loyola Center for Health at Burr Ridge, Burr Ridge, Illinois, United States
Illinois CancerCare-Canton, Canton, Illinois, United States
Memorial Hospital of Carbondale, Carbondale, Illinois, United States
SIH Cancer Institute, Carterville, Illinois, United States
Illinois CancerCare-Carthage, Carthage, Illinois, United States
Northwestern University, Chicago, Illinois, United States
Rush University Medical Center, Chicago, Illinois, United States
University of Illinois, Chicago, Illinois, United States
University of Chicago Comprehensive Cancer Center, Chicago, Illinois, United States
Carle at The Riverfront, Danville, Illinois, United States
Cancer Care Specialists of Illinois - Decatur, Decatur, Illinois, United States
Decatur Memorial Hospital, Decatur, Illinois, United States
Illinois CancerCare-Dixon, Dixon, Illinois, United States
Carle Physician Group-Effingham, Effingham, Illinois, United States
Crossroads Cancer Center, Effingham, Illinois, United States
Illinois CancerCare-Eureka, Eureka, Illinois, United States
Illinois CancerCare-Galesburg, Galesburg, Illinois, United States
Western Illinois Cancer Treatment Center, Galesburg, Illinois, United States
Loyola Medicine Homer Glen, Homer Glen, Illinois, United States
Illinois CancerCare-Kewanee Clinic, Kewanee, Illinois, United States
Northwestern Medicine Lake Forest Hospital, Lake Forest, Illinois, United States
Illinois CancerCare-Macomb, Macomb, Illinois, United States
Carle Physician Group-Mattoon/Charleston, Mattoon, Illinois, United States
Loyola University Medical Center, Maywood, Illinois, United States
Marjorie Weinberg Cancer Center at Loyola-Gottlieb, Melrose Park, Illinois, United States
Good Samaritan Regional Health Center, Mount Vernon, Illinois, United States
UC Comprehensive Cancer Center at Silver Cross, New Lenox, Illinois, United States
Cancer Care Center of O'Fallon, O'Fallon, Illinois, United States
University of Chicago Medicine-Orland Park, Orland Park, Illinois, United States
Illinois CancerCare-Ottawa Clinic, Ottawa, Illinois, United States
Illinois CancerCare-Pekin, Pekin, Illinois, United States
Illinois CancerCare-Peoria, Peoria, Illinois, United States
Methodist Medical Center of Illinois, Peoria, Illinois, United States
Illinois CancerCare-Peru, Peru, Illinois, United States
Valley Radiation Oncology, Peru, Illinois, United States
Illinois CancerCare-Princeton, Princeton, Illinois, United States
Southern Illinois University School of Medicine, Springfield, Illinois, United States
Springfield Clinic, Springfield, Illinois, United States
Memorial Medical Center, Springfield, Illinois, United States
Southwest Illinois Health Services LLP, Swansea, Illinois, United States
Carle Cancer Center, Urbana, Illinois, United States
The Carle Foundation Hospital, Urbana, Illinois, United States
Illinois CancerCare - Washington, Washington, Illinois, United States
Rush-Copley Healthcare Center, Yorkville, Illinois, United States
Reid Health, Richmond, Indiana, United States
Mary Greeley Medical Center, Ames, Iowa, United States
McFarland Clinic - Ames, Ames, Iowa, United States
McFarland Clinic - Boone, Boone, Iowa, United States
Mercy Cancer Center-West Lakes, Clive, Iowa, United States
Mission Cancer and Blood - West Des Moines, Clive, Iowa, United States
Alegent Health Mercy Hospital, Council Bluffs, Iowa, United States
Greater Regional Medical Center, Creston, Iowa, United States
Mercy Medical Center - Des Moines, Des Moines, Iowa, United States
Mission Cancer and Blood - Laurel, Des Moines, Iowa, United States
McFarland Clinic - Trinity Cancer Center, Fort Dodge, Iowa, United States
McFarland Clinic - Jefferson, Jefferson, Iowa, United States
McFarland Clinic - Marshalltown, Marshalltown, Iowa, United States
Mercy Medical Center-West Lakes, West Des Moines, Iowa, United States
Cancer Center of Kansas - Chanute, Chanute, Kansas, United States
Cancer Center of Kansas - Dodge City, Dodge City, Kansas, United States
Cancer Center of Kansas - El Dorado, El Dorado, Kansas, United States
University of Kansas Clinical Research Center, Fairway, Kansas, United States
Central Care Cancer Center - Garden City, Garden City, Kansas, United States
Central Care Cancer Center - Great Bend, Great Bend, Kansas, United States
HaysMed, Hays, Kansas, United States
Cancer Center of Kansas-Independence, Independence, Kansas, United States
Cancer Center of Kansas-Kingman, Kingman, Kansas, United States
Lawrence Memorial Hospital, Lawrence, Kansas, United States
Cancer Center of Kansas-Liberal, Liberal, Kansas, United States
Cancer Center of Kansas-Manhattan, Manhattan, Kansas, United States
Cancer Center of Kansas - McPherson, McPherson, Kansas, United States
Cancer Center of Kansas - Newton, Newton, Kansas, United States
Olathe Health Cancer Center, Olathe, Kansas, United States
Cancer Center of Kansas - Parsons, Parsons, Kansas, United States
Ascension Via Christi - Pittsburg, Pittsburg, Kansas, United States
Freeman Physician Group of Pittsburg, Pittsburg, Kansas, United States
Cancer Center of Kansas - Pratt, Pratt, Kansas, United States
Cancer Center of Kansas - Salina, Salina, Kansas, United States
Salina Regional Health Center, Salina, Kansas, United States
University of Kansas Health System Saint Francis Campus, Topeka, Kansas, United States
Cancer Center of Kansas - Wellington, Wellington, Kansas, United States
University of Kansas Hospital-Westwood Cancer Center, Westwood, Kansas, United States
Cancer Center of Kansas-Wichita Medical Arts Tower, Wichita, Kansas, United States
Ascension Via Christi Hospitals Wichita, Wichita, Kansas, United States
Cancer Center of Kansas - Wichita, Wichita, Kansas, United States
Cancer Center of Kansas - Winfield, Winfield, Kansas, United States
Flaget Memorial Hospital, Bardstown, Kentucky, United States
Commonwealth Cancer Center-Corbin, Corbin, Kentucky, United States
Saint Joseph Radiation Oncology Resource Center, Lexington, Kentucky, United States
Saint Joseph Hospital East, Lexington, Kentucky, United States
University of Kentucky/Markey Cancer Center, Lexington, Kentucky, United States
Saint Joseph London, London, Kentucky, United States
Jewish Hospital, Louisville, Kentucky, United States
Saints Mary and Elizabeth Hospital, Louisville, Kentucky, United States
UofL Health Medical Center Northeast, Louisville, Kentucky, United States
Jewish Hospital Medical Center South, Shepherdsville, Kentucky, United States
Hematology/Oncology Clinic PLLC, Baton Rouge, Louisiana, United States
Ochsner High Grove, Baton Rouge, Louisiana, United States
Ochsner Medical Center Kenner, Kenner, Louisiana, United States
East Jefferson General Hospital, Metairie, Louisiana, United States
LSU Healthcare Network / Metairie Multi-Specialty Clinic, Metairie, Louisiana, United States
Louisiana State University Health Science Center, New Orleans, Louisiana, United States
Tulane University School of Medicine, New Orleans, Louisiana, United States
Ochsner Medical Center Jefferson, New Orleans, Louisiana, United States
Greater Baltimore Medical Center, Baltimore, Maryland, United States
National Institutes of Health Clinical Center, Bethesda, Maryland, United States
Lahey Hospital and Medical Center, Burlington, Massachusetts, United States
Lahey Medical Center-Peabody, Peabody, Massachusetts, United States
Mercy Medical Center, Springfield, Massachusetts, United States
Winchester Hospital, Winchester, Massachusetts, United States
Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor, Michigan, United States
Trinity Health IHA Medical Group Hematology Oncology - Brighton, Brighton, Michigan, United States
Trinity Health Medical Center - Brighton, Brighton, Michigan, United States
Henry Ford Cancer Institute-Downriver, Brownstown, Michigan, United States
Trinity Health IHA Medical Group Hematology Oncology - Canton, Canton, Michigan, United States
Trinity Health Medical Center - Canton, Canton, Michigan, United States
Caro Cancer Center, Caro, Michigan, United States
Saint Joseph Mercy Chelsea, Chelsea, Michigan, United States
Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital, Chelsea, Michigan, United States
Hematology Oncology Consultants-Clarkston, Clarkston, Michigan, United States
Newland Medical Associates-Clarkston, Clarkston, Michigan, United States
Henry Ford Macomb Hospital-Clinton Township, Clinton Township, Michigan, United States
Henry Ford Medical Center-Fairlane, Dearborn, Michigan, United States
Henry Ford Hospital, Detroit, Michigan, United States
Ascension Saint John Hospital, Detroit, Michigan, United States
Great Lakes Cancer Management Specialists-Doctors Park, East China Township, Michigan, United States
Genesee Cancer and Blood Disease Treatment Center, Flint, Michigan, United States
Genesee Hematology Oncology PC, Flint, Michigan, United States
Genesys Hurley Cancer Institute, Flint, Michigan, United States
Hurley Medical Center, Flint, Michigan, United States
Academic Hematology Oncology Specialists, Grosse Pointe Woods, Michigan, United States
Great Lakes Cancer Management Specialists-Van Elslander Cancer Center, Grosse Pointe Woods, Michigan, United States
Michigan Breast Specialists-Grosse Pointe Woods, Grosse Pointe Woods, Michigan, United States
Allegiance Health, Jackson, Michigan, United States
University of Michigan Health - Sparrow Lansing, Lansing, Michigan, United States
Hope Cancer Clinic, Livonia, Michigan, United States
Trinity Health Saint Mary Mercy Livonia Hospital, Livonia, Michigan, United States
Great Lakes Cancer Management Specialists-Macomb Medical Campus, Macomb, Michigan, United States
Michigan Breast Specialists-Macomb Township, Macomb, Michigan, United States
Saint Mary's Oncology/Hematology Associates of Marlette, Marlette, Michigan, United States
Henry Ford Medical Center-Columbus, Novi, Michigan, United States
Hope Cancer Center, Pontiac, Michigan, United States
Michigan Healthcare Professionals Pontiac, Pontiac, Michigan, United States
Newland Medical Associates-Pontiac, Pontiac, Michigan, United States
Trinity Health Saint Joseph Mercy Oakland Hospital, Pontiac, Michigan, United States
Huron Medical Center PC, Port Huron, Michigan, United States
Lake Huron Medical Center, Port Huron, Michigan, United States
Great Lakes Cancer Management Specialists-Rochester Hills, Rochester Hills, Michigan, United States
Ascension Saint Mary's Hospital, Saginaw, Michigan, United States
Oncology Hematology Associates of Saginaw Valley PC, Saginaw, Michigan, United States
Henry Ford Macomb Health Center - Shelby Township, Shelby, Michigan, United States
Bhadresh Nayak MD PC-Sterling Heights, Sterling Heights, Michigan, United States
Ascension Saint Joseph Hospital, Tawas City, Michigan, United States
Advanced Breast Care Center PLLC, Warren, Michigan, United States
Great Lakes Cancer Management Specialists-Macomb Professional Building, Warren, Michigan, United States
Macomb Hematology Oncology PC, Warren, Michigan, United States
Michigan Breast Specialists-Warren, Warren, Michigan, United States
Saint John Macomb-Oakland Hospital, Warren, Michigan, United States
Henry Ford West Bloomfield Hospital, West Bloomfield, Michigan, United States
Saint Mary's Oncology/Hematology Associates of West Branch, West Branch, Michigan, United States
Huron Gastroenterology PC, Ypsilanti, Michigan, United States
Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti, Michigan, United States
Riverwood Healthcare Center, Aitkin, Minnesota, United States
Essentia Health Saint Joseph's Medical Center, Brainerd, Minnesota, United States
Fairview Ridges Hospital, Burnsville, Minnesota, United States
Minnesota Oncology - Burnsville, Burnsville, Minnesota, United States
Cambridge Medical Center, Cambridge, Minnesota, United States
Mercy Hospital, Coon Rapids, Minnesota, United States
Essentia Health - Deer River Clinic, Deer River, Minnesota, United States
Essentia Health Saint Mary's - Detroit Lakes Clinic, Detroit Lakes, Minnesota, United States
Essentia Health Cancer Center, Duluth, Minnesota, United States
Essentia Health Saint Mary's Medical Center, Duluth, Minnesota, United States
Miller-Dwan Hospital, Duluth, Minnesota, United States
Fairview Southdale Hospital, Edina, Minnesota, United States
Lake Region Healthcare Corporation-Cancer Care, Fergus Falls, Minnesota, United States
Essentia Health - Fosston, Fosston, Minnesota, United States
Unity Hospital, Fridley, Minnesota, United States
Essentia Health Hibbing Clinic, Hibbing, Minnesota, United States
Fairview Clinics and Surgery Center Maple Grove, Maple Grove, Minnesota, United States
Minnesota Oncology Hematology PA-Maplewood, Maplewood, Minnesota, United States
Saint John's Hospital - Healtheast, Maplewood, Minnesota, United States
Abbott-Northwestern Hospital, Minneapolis, Minnesota, United States
Hennepin County Medical Center, Minneapolis, Minnesota, United States
Health Partners Inc, Minneapolis, Minnesota, United States
Monticello Cancer Center, Monticello, Minnesota, United States
New Ulm Medical Center, New Ulm, Minnesota, United States
Essentia Health - Park Rapids, Park Rapids, Minnesota, United States
Fairview Northland Medical Center, Princeton, Minnesota, United States
North Memorial Medical Health Center, Robbinsdale, Minnesota, United States
Mayo Clinic in Rochester, Rochester, Minnesota, United States
Park Nicollet Clinic - Saint Louis Park, Saint Louis Park, Minnesota, United States
Regions Hospital, Saint Paul, Minnesota, United States
United Hospital, Saint Paul, Minnesota, United States
Essentia Health Sandstone, Sandstone, Minnesota, United States
Saint Francis Regional Medical Center, Shakopee, Minnesota, United States
Lakeview Hospital, Stillwater, Minnesota, United States
Essentia Health Virginia Clinic, Virginia, Minnesota, United States
Ridgeview Medical Center, Waconia, Minnesota, United States
Rice Memorial Hospital, Willmar, Minnesota, United States
Minnesota Oncology Hematology PA-Woodbury, Woodbury, Minnesota, United States
Fairview Lakes Medical Center, Wyoming, Minnesota, United States
University of Mississippi Medical Center, Jackson, Mississippi, United States
Saint Louis Cancer and Breast Institute-Ballwin, Ballwin, Missouri, United States
Central Care Cancer Center - Bolivar, Bolivar, Missouri, United States
Parkland Health Center-Bonne Terre, Bonne Terre, Missouri, United States
Cox Cancer Center Branson, Branson, Missouri, United States
Saint Francis Medical Center, Cape Girardeau, Missouri, United States
Southeast Cancer Center, Cape Girardeau, Missouri, United States
Siteman Cancer Center at West County Hospital, Creve Coeur, Missouri, United States
Parkland Health Center - Farmington, Farmington, Missouri, United States
MU Health Care Goldschmidt Cancer Center, Jefferson City, Missouri, United States
Freeman Health System, Joplin, Missouri, United States
Mercy Hospital Joplin, Joplin, Missouri, United States
University Health Truman Medical Center, Kansas City, Missouri, United States
University of Kansas Cancer Center - Lee's Summit, Lee's Summit, Missouri, United States
Delbert Day Cancer Institute at PCRMC, Rolla, Missouri, United States
Mercy Clinic-Rolla-Cancer and Hematology, Rolla, Missouri, United States
Heartland Regional Medical Center, Saint Joseph, Missouri, United States
Saint Louis Cancer and Breast Institute-South City, Saint Louis, Missouri, United States
Washington University School of Medicine, Saint Louis, Missouri, United States
Mercy Hospital South, Saint Louis, Missouri, United States
Siteman Cancer Center-South County, Saint Louis, Missouri, United States
Missouri Baptist Medical Center, Saint Louis, Missouri, United States
Siteman Cancer Center at Christian Hospital, Saint Louis, Missouri, United States
Mercy Hospital Saint Louis, Saint Louis, Missouri, United States
Siteman Cancer Center at Saint Peters Hospital, Saint Peters, Missouri, United States
Sainte Genevieve County Memorial Hospital, Sainte Genevieve, Missouri, United States
Mercy Hospital Springfield, Springfield, Missouri, United States
CoxHealth South Hospital, Springfield, Missouri, United States
Missouri Baptist Sullivan Hospital, Sullivan, Missouri, United States
BJC Outpatient Center at Sunset Hills, Sunset Hills, Missouri, United States
Mercy Hospital Washington, Washington, Missouri, United States
Community Hospital of Anaconda, Anaconda, Montana, United States
Billings Clinic Cancer Center, Billings, Montana, United States
Bozeman Health Deaconess Hospital, Bozeman, Montana, United States
Benefis Sletten Cancer Institute, Great Falls, Montana, United States
Great Falls Clinic, Great Falls, Montana, United States
Saint Peter's Community Hospital, Helena, Montana, United States
Kalispell Regional Medical Center, Kalispell, Montana, United States
Saint Patrick Hospital - Community Hospital, Missoula, Montana, United States
Community Medical Center, Missoula, Montana, United States
Nebraska Medicine-Bellevue, Bellevue, Nebraska, United States
Nebraska Cancer Specialists/Oncology Hematology West PC, Grand Island, Nebraska, United States
CHI Health Good Samaritan, Kearney, Nebraska, United States
Saint Elizabeth Regional Medical Center, Lincoln, Nebraska, United States
Nebraska Cancer Specialists/Oncology Hematology West PC - MECC, Omaha, Nebraska, United States
Nebraska Methodist Hospital, Omaha, Nebraska, United States
Oncology Associates PC, Omaha, Nebraska, United States
Nebraska Medicine-Village Pointe, Omaha, Nebraska, United States
Alegent Health Immanuel Medical Center, Omaha, Nebraska, United States
Alegent Health Bergan Mercy Medical Center, Omaha, Nebraska, United States
Alegent Health Lakeside Hospital, Omaha, Nebraska, United States
Creighton University Medical Center, Omaha, Nebraska, United States
University of Nebraska Medical Center, Omaha, Nebraska, United States
Midlands Community Hospital, Papillion, Nebraska, United States
Carson Tahoe Regional Medical Center, Carson City, Nevada, United States
Cancer and Blood Specialists-Henderson, Henderson, Nevada, United States
Comprehensive Cancer Centers of Nevada - Henderson, Henderson, Nevada, United States
Comprehensive Cancer Centers of Nevada-Horizon Ridge, Henderson, Nevada, United States
Las Vegas Cancer Center-Henderson, Henderson, Nevada, United States
OptumCare Cancer Care at Seven Hills, Henderson, Nevada, United States
Comprehensive Cancer Centers of Nevada-Southeast Henderson, Henderson, Nevada, United States
GenesisCare USA - Henderson, Henderson, Nevada, United States
Las Vegas Urology - Green Valley, Henderson, Nevada, United States
Las Vegas Urology - Pebble, Henderson, Nevada, United States
Urology Specialists of Nevada - Green Valley, Henderson, Nevada, United States
Las Vegas Urology - Pecos, Las Vegas, Nevada, United States
Desert West Surgery, Las Vegas, Nevada, United States
OptumCare Cancer Care at Charleston, Las Vegas, Nevada, United States
University Medical Center of Southern Nevada, Las Vegas, Nevada, United States
Hope Cancer Care of Nevada, Las Vegas, Nevada, United States
Cancer and Blood Specialists-Shadow, Las Vegas, Nevada, United States
Radiation Oncology Centers of Nevada Central, Las Vegas, Nevada, United States
Urology Specialists of Nevada - Central, Las Vegas, Nevada, United States
GenesisCare USA - Las Vegas, Las Vegas, Nevada, United States
HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway, Las Vegas, Nevada, United States
Sunrise Hospital and Medical Center, Las Vegas, Nevada, United States
HealthCare Partners Medical Group Oncology/Hematology-San Martin, Las Vegas, Nevada, United States
Las Vegas Prostate Cancer Center, Las Vegas, Nevada, United States
Las Vegas Urology - Sunset, Las Vegas, Nevada, United States
Urology Specialists of Nevada - Southwest, Las Vegas, Nevada, United States
Radiation Oncology Centers of Nevada Southeast, Las Vegas, Nevada, United States
Ann M Wierman MD LTD, Las Vegas, Nevada, United States
Cancer and Blood Specialists-Tenaya, Las Vegas, Nevada, United States
Comprehensive Cancer Centers of Nevada - Northwest, Las Vegas, Nevada, United States
GenesisCare USA - Vegas Tenaya, Las Vegas, Nevada, United States
HealthCare Partners Medical Group Oncology/Hematology-Tenaya, Las Vegas, Nevada, United States
Las Vegas Urology - Cathedral Rock, Las Vegas, Nevada, United States
Las Vegas Urology - Smoke Ranch, Las Vegas, Nevada, United States
OptumCare Cancer Care at MountainView, Las Vegas, Nevada, United States
Urology Specialists of Nevada - Northwest, Las Vegas, Nevada, United States
Alliance for Childhood Diseases/Cure 4 the Kids Foundation, Las Vegas, Nevada, United States
Comprehensive Cancer Centers of Nevada - Town Center, Las Vegas, Nevada, United States
Comprehensive Cancer Centers of Nevada-Summerlin, Las Vegas, Nevada, United States
Summerlin Hospital Medical Center, Las Vegas, Nevada, United States
Las Vegas Cancer Center-Medical Center, Las Vegas, Nevada, United States
Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada, United States
GenesisCare USA - Fort Apache, Las Vegas, Nevada, United States
OptumCare Cancer Care at Fort Apache, Las Vegas, Nevada, United States
HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills, Las Vegas, Nevada, United States
Comprehensive Cancer Centers of Nevada - Central Valley, Las Vegas, Nevada, United States
University Cancer Center, Las Vegas, Nevada, United States
Hope Cancer Care of Nevada-Pahrump, Pahrump, Nevada, United States
Renown Regional Medical Center, Reno, Nevada, United States
Saint Mary's Regional Medical Center, Reno, Nevada, United States
Radiation Oncology Associates, Reno, Nevada, United States
Memorial Sloan Kettering Basking Ridge, Basking Ridge, New Jersey, United States
Memorial Sloan Kettering Monmouth, Middletown, New Jersey, United States
Memorial Sloan Kettering Bergen, Montvale, New Jersey, United States
New York-Presbyterian/Brooklyn Methodist Hospital, Brooklyn, New York, United States
Maimonides Medical Center, Brooklyn, New York, United States
Roswell Park Cancer Institute, Buffalo, New York, United States
Memorial Sloan Kettering Commack, Commack, New York, United States
Memorial Sloan Kettering Westchester, Harrison, New York, United States
Northwell Health/Center for Advanced Medicine, Lake Success, New York, United States
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York, New York, United States
Memorial Sloan Kettering Cancer Center, New York, New York, United States
NYP/Weill Cornell Medical Center, New York, New York, United States
University of Rochester, Rochester, New York, United States
State University of New York Upstate Medical University, Syracuse, New York, United States
Memorial Sloan Kettering Nassau, Uniondale, New York, United States
UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina, United States
Margaret R Pardee Memorial Hospital, Hendersonville, North Carolina, United States
Essentia Health Cancer Center-South University Clinic, Fargo, North Dakota, United States
Essentia Health - Jamestown Clinic, Jamestown, North Dakota, United States
Indu and Raj Soin Medical Center, Beavercreek, Ohio, United States
Strecker Cancer Center-Belpre, Belpre, Ohio, United States
Saint Elizabeth Boardman Hospital, Boardman, Ohio, United States
Dayton Physicians LLC-Miami Valley South, Centerville, Ohio, United States
Miami Valley Hospital South, Centerville, Ohio, United States
Adena Regional Medical Center, Chillicothe, Ohio, United States
University of Cincinnati Cancer Center-UC Medical Center, Cincinnati, Ohio, United States
Good Samaritan Hospital - Cincinnati, Cincinnati, Ohio, United States
Oncology Hematology Care Inc-Kenwood, Cincinnati, Ohio, United States
Bethesda North Hospital, Cincinnati, Ohio, United States
TriHealth Cancer Institute-Westside, Cincinnati, Ohio, United States
TriHealth Cancer Institute-Anderson, Cincinnati, Ohio, United States
Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States
Mount Carmel East Hospital, Columbus, Ohio, United States
Columbus Oncology and Hematology Associates Inc, Columbus, Ohio, United States
Riverside Methodist Hospital, Columbus, Ohio, United States
Grant Medical Center, Columbus, Ohio, United States
The Mark H Zangmeister Center, Columbus, Ohio, United States
Mount Carmel Health Center West, Columbus, Ohio, United States
Doctors Hospital, Columbus, Ohio, United States
Good Samaritan Hospital - Dayton, Dayton, Ohio, United States
Miami Valley Hospital, Dayton, Ohio, United States
Dayton Physician LLC - Englewood, Dayton, Ohio, United States
Miami Valley Hospital North, Dayton, Ohio, United States
Delaware Health Center-Grady Cancer Center, Delaware, Ohio, United States
Grady Memorial Hospital, Delaware, Ohio, United States
Dublin Methodist Hospital, Dublin, Ohio, United States
Armes Family Cancer Center, Findlay, Ohio, United States
Blanchard Valley Hospital, Findlay, Ohio, United States
Orion Cancer Care, Findlay, Ohio, United States
Atrium Medical Center-Middletown Regional Hospital, Franklin, Ohio, United States
Dayton Physicians LLC-Atrium, Franklin, Ohio, United States
Central Ohio Breast and Endocrine Surgery, Gahanna, Ohio, United States
Dayton Physicians LLC-Wayne, Greenville, Ohio, United States
Wayne Hospital, Greenville, Ohio, United States
Mount Carmel Grove City Hospital, Grove City, Ohio, United States
Greater Dayton Cancer Center, Kettering, Ohio, United States
First Dayton Cancer Care, Kettering, Ohio, United States
Kettering Medical Center, Kettering, Ohio, United States
Fairfield Medical Center, Lancaster, Ohio, United States
Saint Rita's Medical Center, Lima, Ohio, United States
OhioHealth Mansfield Hospital, Mansfield, Ohio, United States
Marietta Memorial Hospital, Marietta, Ohio, United States
OhioHealth Marion General Hospital, Marion, Ohio, United States
Memorial Hospital, Marysville, Ohio, United States
Knox Community Hospital, Mount Vernon, Ohio, United States
Licking Memorial Hospital, Newark, Ohio, United States
Newark Radiation Oncology, Newark, Ohio, United States
Mercy Health Perrysburg Cancer Center, Perrysburg, Ohio, United States
Southern Ohio Medical Center, Portsmouth, Ohio, United States
Springfield Regional Cancer Center, Springfield, Ohio, United States
Springfield Regional Medical Center, Springfield, Ohio, United States
Mercy Health - Saint Vincent Hospital, Toledo, Ohio, United States
Mercy Health - Saint Anne Hospital, Toledo, Ohio, United States
Dayton Physicians LLC - Troy, Troy, Ohio, United States
Upper Valley Medical Center, Troy, Ohio, United States
Saint Joseph Warren Hospital, Warren, Ohio, United States
University of Cincinnati Cancer Center-West Chester, West Chester, Ohio, United States
Saint Ann's Hospital, Westerville, Ohio, United States
Saint Elizabeth Youngstown Hospital, Youngstown, Ohio, United States
Genesis Healthcare System Cancer Care Center, Zanesville, Ohio, United States
Cancer Centers of Southwest Oklahoma Research, Lawton, Oklahoma, United States
University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States
Mercy Hospital Oklahoma City, Oklahoma City, Oklahoma, United States
Oklahoma Cancer Specialists and Research Institute-Tulsa, Tulsa, Oklahoma, United States
Saint Alphonsus Medical Center-Baker City, Baker City, Oregon, United States
Saint Charles Health System, Bend, Oregon, United States
Clackamas Radiation Oncology Center, Clackamas, Oregon, United States
Providence Cancer Institute Clackamas Clinic, Clackamas, Oregon, United States
Bay Area Hospital, Coos Bay, Oregon, United States
Providence Newberg Medical Center, Newberg, Oregon, United States
Saint Alphonsus Medical Center-Ontario, Ontario, Oregon, United States
Providence Willamette Falls Medical Center, Oregon City, Oregon, United States
Providence Portland Medical Center, Portland, Oregon, United States
Providence Saint Vincent Medical Center, Portland, Oregon, United States
Oregon Health and Science University, Portland, Oregon, United States
Saint Charles Health System-Redmond, Redmond, Oregon, United States
Lehigh Valley Hospital-Cedar Crest, Allentown, Pennsylvania, United States
Lehigh Valley Hospital - Muhlenberg, Bethlehem, Pennsylvania, United States
Pocono Medical Center, East Stroudsburg, Pennsylvania, United States
UPMC Hillman Cancer Center Erie, Erie, Pennsylvania, United States
Saint Vincent Hospital, Erie, Pennsylvania, United States
UPMC Cancer Centers - Arnold Palmer Pavilion, Greensburg, Pennsylvania, United States
Lehigh Valley Hospital-Hazleton, Hazleton, Pennsylvania, United States
Jefferson Hospital, Jefferson Hills, Pennsylvania, United States
Forbes Hospital, Monroeville, Pennsylvania, United States
UPMC Cancer Center - Monroeville, Monroeville, Pennsylvania, United States
UPMC Hillman Cancer Center - Monroeville, Monroeville, Pennsylvania, United States
Arnold Palmer Cancer Center Medical Oncology Norwin, N. Huntingdon, Pennsylvania, United States
Allegheny Valley Hospital, Natrona Heights, Pennsylvania, United States
Allegheny General Hospital, Pittsburgh, Pennsylvania, United States
West Penn Hospital, Pittsburgh, Pennsylvania, United States
University of Pittsburgh Cancer Institute (UPCI), Pittsburgh, Pennsylvania, United States
UPMC-Shadyside Hospital, Pittsburgh, Pennsylvania, United States
UPMC-Passavant Hospital, Pittsburgh, Pennsylvania, United States
UPMC-Saint Clair Hospital Cancer Center, Pittsburgh, Pennsylvania, United States
Wexford Health and Wellness Pavilion, Wexford, Pennsylvania, United States
Medical University of South Carolina, Charleston, South Carolina, United States
University Cancer Specialists - Alcoa, Alcoa, Tennessee, United States
Vanderbilt-Ingram Cancer Center Cool Springs, Franklin, Tennessee, United States
University of Tennessee - Knoxville, Knoxville, Tennessee, United States
Vanderbilt Breast Center at One Hundred Oaks, Nashville, Tennessee, United States
Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee, United States
Saint Joseph Regional Cancer Center, Bryan, Texas, United States
UT Southwestern Simmons Cancer Center - RedBird, Dallas, Texas, United States
UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas, United States
UT Southwestern/Simmons Cancer Center-Fort Worth, Fort Worth, Texas, United States
UT Southwestern Clinical Center at Richardson/Plano, Richardson, Texas, United States
Providence Regional Cancer System-Aberdeen, Aberdeen, Washington, United States
Overlake Medical Center, Bellevue, Washington, United States
PeaceHealth Saint Joseph Medical Center, Bellingham, Washington, United States
Harrison HealthPartners Hematology and Oncology-Bremerton, Bremerton, Washington, United States
Highline Medical Center-Main Campus, Burien, Washington, United States
Providence Regional Cancer System-Centralia, Centralia, Washington, United States
Swedish Cancer Institute-Edmonds, Edmonds, Washington, United States
Saint Elizabeth Hospital, Enumclaw, Washington, United States
Providence Regional Cancer Partnership, Everett, Washington, United States
Saint Francis Hospital, Federal Way, Washington, United States
Swedish Cancer Institute-Issaquah, Issaquah, Washington, United States
Kadlec Clinic Hematology and Oncology, Kennewick, Washington, United States
Providence Regional Cancer System-Lacey, Lacey, Washington, United States
Saint Clare Hospital, Lakewood, Washington, United States
PeaceHealth Saint John Medical Center, Longview, Washington, United States
Harrison HealthPartners Hematology and Oncology-Poulsbo, Poulsbo, Washington, United States
Valley Medical Center, Renton, Washington, United States
Pacific Gynecology Specialists, Seattle, Washington, United States
Swedish Medical Center-Ballard Campus, Seattle, Washington, United States
Swedish Medical Center-Cherry Hill, Seattle, Washington, United States
Swedish Medical Center-First Hill, Seattle, Washington, United States
PeaceHealth United General Medical Center, Sedro-Woolley, Washington, United States
Providence Regional Cancer System-Shelton, Shelton, Washington, United States
Saint Michael Cancer Center, Silverdale, Washington, United States
Franciscan Research Center-Northwest Medical Plaza, Tacoma, Washington, United States
Northwest Medical Specialties PLLC, Tacoma, Washington, United States
PeaceHealth Southwest Medical Center, Vancouver, Washington, United States
Providence Saint Mary Regional Cancer Center, Walla Walla, Washington, United States
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital, Yakima, Washington, United States
Providence Regional Cancer System-Yelm, Yelm, Washington, United States
Duluth Clinic Ashland, Ashland, Wisconsin, United States
Northwest Wisconsin Cancer Center, Ashland, Wisconsin, United States
Aurora Cancer Care-Southern Lakes VLCC, Burlington, Wisconsin, United States
Aurora Saint Luke's South Shore, Cudahy, Wisconsin, United States
Marshfield Medical Center-EC Cancer Center, Eau Claire, Wisconsin, United States
Mayo Clinic Health System-Eau Claire Clinic, Eau Claire, Wisconsin, United States
Aurora Health Care Germantown Health Center, Germantown, Wisconsin, United States
Aurora Cancer Care-Grafton, Grafton, Wisconsin, United States
Aurora BayCare Medical Center, Green Bay, Wisconsin, United States
Aurora Cancer Care-Kenosha South, Kenosha, Wisconsin, United States
Aurora Bay Area Medical Group-Marinette, Marinette, Wisconsin, United States
Marshfield Medical Center-Marshfield, Marshfield, Wisconsin, United States
Aurora Cancer Care-Milwaukee, Milwaukee, Wisconsin, United States
Aurora Saint Luke's Medical Center, Milwaukee, Wisconsin, United States
Aurora Sinai Medical Center, Milwaukee, Wisconsin, United States
Marshfield Clinic-Minocqua Center, Minocqua, Wisconsin, United States
ProHealth D N Greenwald Center, Mukwonago, Wisconsin, United States
Cancer Center of Western Wisconsin, New Richmond, Wisconsin, United States
ProHealth Oconomowoc Memorial Hospital, Oconomowoc, Wisconsin, United States
Vince Lombardi Cancer Clinic - Oshkosh, Oshkosh, Wisconsin, United States
Aurora Cancer Care-Racine, Racine, Wisconsin, United States
Marshfield Medical Center-Rice Lake, Rice Lake, Wisconsin, United States
Vince Lombardi Cancer Clinic-Sheboygan, Sheboygan, Wisconsin, United States
Marshfield Medical Center-River Region at Stevens Point, Stevens Point, Wisconsin, United States
Aurora Medical Center in Summit, Summit, Wisconsin, United States
Vince Lombardi Cancer Clinic-Two Rivers, Two Rivers, Wisconsin, United States
ProHealth Waukesha Memorial Hospital, Waukesha, Wisconsin, United States
UW Cancer Center at ProHealth Care, Waukesha, Wisconsin, United States
Aurora Cancer Care-Milwaukee West, Wauwatosa, Wisconsin, United States
Aurora West Allis Medical Center, West Allis, Wisconsin, United States
Marshfield Medical Center - Weston, Weston, Wisconsin, United States
Billings Clinic-Cody, Cody, Wyoming, United States
Welch Cancer Center, Sheridan, Wyoming, United States
Pan American Center for Oncology Trials LLC, San Juan, , Puerto Rico
Contact Details
Name: Andrea B Apolo
Affiliation: Alliance for Clinical Trials in Oncology
Role: PRINCIPAL_INVESTIGATOR
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