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Spots Global Cancer Trial Database for Urine VOC Investigation in Bladder Cancer Diagnosis

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Trial Identification

Brief Title: Urine VOC Investigation in Bladder Cancer Diagnosis

Official Title: Investigation of Urine Volatile Organic Compounds as Novel Diagnostic Biomarker in Bladder Cancer

Study ID: NCT05671289

Conditions

Bladder Cancer

Study Description

Brief Summary: The goal of this study to investigate the volatile organic compounds (VOCs) in the urine samples of both healthy individual and bladder cancer patients, using gas chromatography - mass spectrometry. Researchers aim to find a set of certain VOCs specific to bladder cancer and use this set to construct a diagnostic model that can help diagnosing bladder cancer. Participants will be asked to collect their early morning midstream urine in a predesignated container. Researchers will compare urine VOCs from bladder cancer patients and healthy individuals to see if there is any VOC whose concentration differ significantly among the two groups.

Detailed Description: Specifically, participants will be asked to collect 35-45 ml of their early morning midstream urine sample in a predesignated polytetrafluoroethylene bottle. Researcher will collect participants' health information, including their: 1)smoking history; 2)comorbidity; 3) history of past urological procedure; 4)medication; 5)pathology diagnosis after surgery, if participants have bladder cancer.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: Yes

Locations

First Affiliated Hospital of Xian Jiaotong University, Xi'an, Shaanxi, China

Contact Details

Name: Jinhai Fan, MD

Affiliation: First affiliated hospital of Xian jiaotong university

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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