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Spots Global Cancer Trial Database for Feasibility of Online Adaptive Radiotherapy for Muscle Invasive Bladder Cancer

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Trial Identification

Brief Title: Feasibility of Online Adaptive Radiotherapy for Muscle Invasive Bladder Cancer

Official Title: A Multicentre Feasibility Study of Online Adaptive Image Guided Radiotherapy for Muscle Invasive Bladder Cancer

Study ID: NCT01142102

Conditions

Bladder Cancer

Interventions

Radiation Therapy

Study Description

Brief Summary: The principal objective of the trial is to test the hypothesis that Online Adaptive Radiotherapy for Muscle Invasive Bladder Cancer is feasible across multiple Radiation Oncology departments.

Detailed Description: This is a single-arm multicentre feasibility trial in which the primary aim is to determine the compliance rate of patients to online adaptive radiotherapy for muscle invasive bladder cancer over multiple Australian and New Zealand centres. The compliance rate is defined as the proportion of patients successfully completing treatment without a major protocol deviation. Subject to the accrual being at least 40 patients in the first 2 years, accrual will continue until a total of 50 patients have been accrued. If this accrual target is not met, then consideration will be given to stopping the trial early due to poor accrual. Each patient will be followed-up until 2 years after the last patient's date of accrual. Assessments for toxicity and recurrence or progression will take place at four weeks after completion of treatment, then three monthly from the end of treatment for the first 12 months and then 6 monthly thereafter.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia

Calvary Mater Newcastle, Newcastle, New South Wales, Australia

Westmead Hospital, Westmead, New South Wales, Australia

Mater Hospital, Brisbane, Queensland, Australia

Townsville Hospital, Douglas, Queensland, Australia

Princess Alexandra Hospital, Woolloongabba, Queensland, Australia

Royal Hobart Hospital, Hobart, Tasmania, Australia

Peter MacCallum Cancer Centre - Box Hill, Melbourne, Victoria, Australia

Peter MacCallum Cancer Centre - Morrabbin, Melbourne, Victoria, Australia

Alfred Hospital, Prahran, Victoria, Australia

Christchurch Hospital, Christchurch, , New Zealand

Waikato Hospital, Waikato, , New Zealand

Contact Details

Name: Dr Farshad Foroudi

Affiliation: Peter MacCallum Cancer Centre, Australia

Role: STUDY_CHAIR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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