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Brief Title: An Efficacy and Safety Study of ICP-192 in Subjects With Bladder Urothelial Cancer
Official Title: A Phase 2, Multicenter, Single Arm, Open-lable Study of ICP-192 in Subjects With Surgically Unresectable or Metastatic Bladder Urothelial Cancer With FGFR Genetic Aberrations.
Study ID: NCT04492293
Brief Summary: This is a phase 2, multicenter, single arm, open-lable study of ICP-192. The purpose of this study is to evaluate efficacy of ICP-192 in subjects with surgically unresectable or metastatic bladder urothelial cancer.
Detailed Description: bladder urothelial cancer
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China
Peking University First Hospital, Beijing, Beijing, China
The fifth Medical Center of People's Liberation Army General Hospital, Beijing, Beijing, China
Beijing Cancer Hospital, Beijing, Beijing, China
The First Affiliated Hospital of Chongqing Medical University, Chongqing, Chongqing, China
Lanzhou University Second Hospital, Lanzhou, Gansu, China
Harbin Medical University Cancer Hospital, Ha'erbin, Heilongjiang, China
Union Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, China
Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, China
Hunan Cancer Hospital, Changsha, Hunan, China
The First Affiliated Hospital of Suzhou University, Suzhou, Jiangsu, China
The First Hospital of JiLin University, Jilin, Jilin, China
Liaoning Cancer Hospital & Institute, Shenyang, Liaoning, China
Shandong University Qilu Hospital, Jinan, Shandong, China
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, Shanghai, China
First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China
Sichuan Cancer Hospital, Chengdu, Sichuan, China
Tianjin Medical University Cancer Institute & Hospital, Tianjin, Tianjin, China
The Second Hospital of Tianjin Medical University, Tianjin, Tianjin, China
The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
Zhejiang Cancer Hospital, Hangzhou, Zhejiang, China
Zhejiang Provincial People's Hospital, Hangzhou, Zhejing, China
Name: Jun Guo
Affiliation: Peking University Cancer Hospital & Institute
Role: PRINCIPAL_INVESTIGATOR