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Brief Title: Trial to Evaluate the Safety and Efficacy of MB-102 in Patients With BPDCN.
Official Title: A Phase 1/2, Open Label, Multicenter Trial to Assess the Safety and Efficacy of MB-102 in Patients With Relapsed or Refractory Blastic Plasmacytoid Dendritic Cell Neoplasm
Study ID: NCT04109482
Brief Summary: A phase 1/2 study to assess the safety and efficacy of MB-102 in patients with relapsed or refractory BPDCN
Detailed Description: The Phase 1 portion of the study will determine the maximum tolerated dose of MB-102. The Phase 2 portion of the trial will evaluate the efficacy of MB-102 in relapsed or refractory BPDCN.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
City of Hope Medical Center, Duarte, California, United States
Dana-Farber Cancer Institute, Boston, Massachusetts, United States
Duke University, Durham, North Carolina, United States
MD Anderson Cancer Center, Houston, Texas, United States
Name: Lihua E Budde, MD
Affiliation: City of Hope Medical Center
Role: PRINCIPAL_INVESTIGATOR