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Brief Title: HLA Sensitization Following Major Cortical Allograft Bone Procedures
Official Title: HLA Sensitization Following Major Cortical Allograft Bone Procedures
Study ID: NCT00160719
Brief Summary: The purpose of this study is to find out whether or not antibodies to the donor bone are present in the blood of patients who receive the donor bone.
Detailed Description: Patients who have bone cancer often have the cancerous bone removed by surgery and replaced with a piece of bone taken from a donor (a person who donates parts of their body to be used for transplants after their death). However, sometimes this replacement bone does not heal together with the patient's bone. The reason the bone does not heal is not known but it is thought that the patient's body may react to the donor bone by producing antibodies against cells on the donor bone. The purpose of this study is to find out whether or not antibodies to the donor bone are present in the blood of patients who receive the donor bone. You have been asked to participate in this study because you are scheduled to undergo this type of surgery.
Minimum Age: 12 Years
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
UF Orthopaedics and Sports Medicine Institute, Gainesville, Florida, United States
Name: Mark T. Scarborough, M.D.
Affiliation: University of Florida
Role: PRINCIPAL_INVESTIGATOR