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Spots Global Cancer Trial Database for Hypofractionated Radiation Therapy With Concomitant Boost in Treating Women After Breast Conserving Surgery

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Trial Identification

Brief Title: Hypofractionated Radiation Therapy With Concomitant Boost in Treating Women After Breast Conserving Surgery

Official Title: Phase II Trial of Hypofractionated Whole-breast Radiation and Concomitant Boost to the Surgical Bed After Breast Conserving Surgery

Study ID: NCT03320421

Interventions

Radiation therapy

Study Description

Brief Summary: This phase II study is to evaluate the safety of hypofractionated whole breast radiation (HFRT) with simultaneous tumor bed boost(SIB) in women with early breast cancer after breast-conserving surgery.

Detailed Description: OBJECTIVES: Primary: To determine the toxicity with adjuvant hypofractionated whole breast radiation with simultaneous tumor bed boost (SIB) in women with early breast cancer after breast conserving surgery. Secondary: To determine the short term cosmetic and quality of life of the participants treated with this regimen. To determine the local control of the participants treated with this regimen. OUTLINE: Patients undergo adjuvant hypofractionated whole breast radiation with simultaneous tumor bed boost once daily a week for 3 weeks. Toxicity, quality of life and cosmetic result is assessed before radiation, at the end of the radiation, within 2, 4, 6 weeks after completion of radiotherapy, and then every 3 months for 1 ear. PROJECTED ACCRUAL: A total of 90 participants will be accrued for this study.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: FEMALE

Healthy Volunteers: No

Locations

National Cancer Center/Cancer Hosptial, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, Beijing, China

Contact Details

Name: Yexiong Li, Professor

Affiliation: Cancer Hospital/Institution, Chinese Academic Medical Sciences and Peking Union Medical College

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

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