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Spots Global Cancer Trial Database for Clinical Implementation of a Polygenic Risk Score (PRS) for Breast Cancer

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We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Clinical Implementation of a Polygenic Risk Score (PRS) for Breast Cancer

Official Title: Clinical Implementation of a Polygenic Risk Score (PRS) for Breast Cancer: Impact on Risk Estimates, Management Recommendations, Clinical Outcomes, and Patient Perception

Study ID: NCT03688204

Interventions

Study Description

Brief Summary: This study aims to assess how a polygenic risk score (PRS) reported with the results of multi-gene panel testing affects the breast cancer risk management recommendations healthcare providers make to their patients. The PRS is a score based on small genetic changes, clinical history, and family history. The PRS is used to estimate remaining lifetime risk of developing breast cancer for patients with no personal history of breast cancer and an overall negative result from MGPT.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: FEMALE

Healthy Volunteers: No

Locations

Providence Roy and Patricia Disney Family Cancer Center, Burbank, California, United States

St Joseph Hospital of Orange, Orange, California, United States

Edwards Comprehensive Cancer Center, Huntington, West Virginia, United States

Contact Details

Name: Brigette Tippin-Davis, PhD

Affiliation: Ambry Genetics

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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