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Spots Global Cancer Trial Database for A Study of Ruxolitinib in Combination With Capecitabine in Subjects With Advanced or Metastatic HER2-negative Breast Cancer

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Trial Identification

Brief Title: A Study of Ruxolitinib in Combination With Capecitabine in Subjects With Advanced or Metastatic HER2-negative Breast Cancer

Official Title: A Randomized, Double-Blind, Phase 2 Study of Ruxolitinib or Placebo in Combination With Capecitabine in Subjects With Advanced or Metastatic HER2-Negative Breast Cancer

Study ID: NCT02120417

Conditions

Breast Cancer

Study Description

Brief Summary: This was a randomized, double-blind, placebo-controlled phase 2 clinical trial comparing the overall survival of women with advanced or metastatic HER2-negative breast cancer who received treatment with capecitabine in combination with ruxolitinib versus those who received treatment with capecitabine alone.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: FEMALE

Healthy Volunteers: No

Locations

, Birmingham, Alabama, United States

, Chandler, Arizona, United States

, Sedona, Arizona, United States

, La Jolla, California, United States

, Los Angeles, California, United States

, Oxnard, California, United States

, San Diego, California, United States

, San Francisco, California, United States

, Santa Monica, California, United States

, Aurora, Colorado, United States

, Denver, Colorado, United States

, New Haven, Connecticut, United States

, Washington, District of Columbia, United States

, Fort Myers, Florida, United States

, Hialeah, Florida, United States

, Miami, Florida, United States

, Plantation, Florida, United States

, Saint Petersburg, Florida, United States

, Tampa, Florida, United States

, Atlanta, Georgia, United States

, Marietta, Georgia, United States

, Savannah, Georgia, United States

, Chicago, Illinois, United States

, Quincy, Illinois, United States

, Springfield, Illinois, United States

, Urbana, Illinois, United States

, Ames, Iowa, United States

, Wichita, Kansas, United States

, Louisville, Kentucky, United States

, Baton Rouge, Louisiana, United States

, Baltimore, Maryland, United States

, Detroit, Michigan, United States

, Kalamazoo, Michigan, United States

, Duluth, Minnesota, United States

, Minneapolis, Minnesota, United States

, Kansas City, Missouri, United States

, Saint Louis, Missouri, United States

, Grand Island, Nebraska, United States

, Omaha, Nebraska, United States

, Camden, New Jersey, United States

, Hackensack, New Jersey, United States

, Farmington, New Mexico, United States

, Albany, New York, United States

, Bronx, New York, United States

, Johnson City, New York, United States

, New York, New York, United States

, Goldsboro, North Carolina, United States

, Pinehurst, North Carolina, United States

, Canton, Ohio, United States

, Cincinnati, Ohio, United States

, Cleveland, Ohio, United States

, Columbus, Ohio, United States

, Middletown, Ohio, United States

, Portland, Oregon, United States

, Bethlehem, Pennsylvania, United States

, Philadelphia, Pennsylvania, United States

, Pittsburgh, Pennsylvania, United States

, Charleston, South Carolina, United States

, Greenville, South Carolina, United States

, Chattanooga, Tennessee, United States

, Germantown, Tennessee, United States

, Nashville, Tennessee, United States

, Arlington, Texas, United States

, Bedford, Texas, United States

, Dallas, Texas, United States

, El Paso, Texas, United States

, Fort Worth, Texas, United States

, Houston, Texas, United States

, McAllen, Texas, United States

, Plano, Texas, United States

, Tyler, Texas, United States

, Ogden, Utah, United States

, Salt Lake City, Utah, United States

, Fairfax, Virginia, United States

, Norfolk, Virginia, United States

, Richmond, Virginia, United States

, Salem, Virginia, United States

, Seattle, Washington, United States

, Green Bay, Wisconsin, United States

, Milwaukee, Wisconsin, United States

, La Roche Sur Yon, , France

, Paris Cedex 10, , France

, Paris, , France

, Alba, , Italy

, Fano, , Italy

, Foggia, , Italy

, Lecco, , Italy

, Milano, , Italy

, Naples, , Italy

, Pontedera, , Italy

, Roma, , Italy

, Saronno, , Italy

, Lisbon, , Portugal

, A Coruña, , Spain

, Barcelona, , Spain

, Jaén, , Spain

, Lleida, , Spain

, Madrid, , Spain

, Cardiff, , United Kingdom

, Glasgow, , United Kingdom

, Kingston Upon Thames, , United Kingdom

, London, , United Kingdom

, Nottingham, , United Kingdom

, Sutton, , United Kingdom

, Taunton, , United Kingdom

, Truro, , United Kingdom

, Yeovil, , United Kingdom

Contact Details

Name: Gerard Kennealey, MD

Affiliation: Incyte Corporation

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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