Spots Global Cancer Trial Database for Validation of the CPS+EG, Neo-Bioscore and Modified Neo-Bioscore Staging Systems After PST of BC in China
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Trial Identification
Brief Title: Validation of the CPS+EG, Neo-Bioscore and Modified Neo-Bioscore Staging Systems After PST of BC in China
Official Title: Validation of CPS+EG, Neo-Bioscore and Modified Neo-Bioscore Staging System After Preoperative Systemic Therapy of Breast Cancer in Multi-center in China
Study ID: NCT03437837
Interventions
Study Description
Brief Summary: Prognostic assessment after preoperative systemic therapy (PST) plays a vital role in breast cancer patients. The clinical-pathologic staging system incorporating estrogen receptor (ER)-negative disease and nuclear grade 3 tumor pathology (CPS+EG staging system) can effectively predict prognosis after PST. The Neo-Bioscore has been developed by the incorporation of the human epidermal growth factor receptor 2 (HER2) status into the CPS+EG staging system. But in a real world in China, the both staging systems had limits because of trastuzumab administration varied a lot in China from the United States. This retrospective study will validate CPS+EG and Neo-Bioscore system and explored a modified Neo-Bioscore system in multiple centers.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Peking University First Hospital, Beijing, Beijing, China
Peking University People's Hospital, Beijing, Beijing, China
Affiliated Hospital of Academy of Military Medical Sciences, Beijing, Beijing, China
Affiliated Union Hospital of Fujian Medical University, Fuzhou, Fujian, China
The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China
The 4th Hospital of Hebei medical university, Shijiazhuang, Hebei, China
The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China
Henan Cancer Hospital, Zhengzhou, Henan, China
The First Hospital of Jilin University, Changchun, Jilin, China
The First Hospital of China Medical University, Shenyang, Liaoning, China, Shenyang, Liaoning, China
Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, China
Second Affiliated Hospital of Shantou University Medical College, Jinan, Shandong, China
Contact Details
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