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Brief Title: Impact of Omega 3 Fatty Acid Supplementation on Aromatase in Obese Subjects
Official Title: A Phase 0, Investigator Initiated Study, Evaluating the Impact of Omega 3 Fatty Acid Supplementation on Aromatase in Obese Postmenopausal Women With Estrogen Receptor Positive Breast Cancer
Study ID: NCT02538484
Brief Summary: Assess the impact of dietary omega 3 free fatty acids and/or letrozole on obese, postmenopausal breast cancer patients.
Detailed Description: Prospective, comparative, three arm, short term, non-interventional study with correlative biomarker endpoints. Sixty (60) obese (≥ 30 BMI) newly diagnosed ER+ postmenopausal breast cancer patients will be recruited to participate in a short term (30 day) Phase 0 biomarker evaluation study prior to surgical resection.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Houston Methodist Cancer Center at Texas Medical Center, Houston, Texas, United States
Mays Cancer Center, UT Health San Antonio, San Antonio, Texas, United States
Name: Andrew Brenner, MD, PhD
Affiliation: Principal Investigator
Role: PRINCIPAL_INVESTIGATOR