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Brief Title: Safety and Efficacy of INCB007839 With Trastuzumab and Vinorelbine in Patients With Metastatic HER2+ Breast Cancer
Official Title: A Phase I/II Study to Assess the Safety and Therapeutic Effect of INCB007839 in Combination With Trastuzumab and Vinorelbine in Patients With Metastatic HER2+ Breast Cancer.
Study ID: NCT01254136
Brief Summary: This Phase I/II study is designed to assess the safety and therapeutic effect of INCB007839 in combination with trastuzumab and vinorelbine in patients with metastatic HER2+ breast cancer.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
, Fayetteville, Arkansas, United States
, Duarte, California, United States
, Denver, Colorado, United States
, Davie, Florida, United States
, Jacksonville, Florida, United States
, Detroit, Michigan, United States
, St. Louis, Missouri, United States
, Hackensack, New Jersey, United States
, Lake Success, New York, United States
, Huntersville, North Carolina, United States
, Cincinnati, Ohio, United States
, Philadelphia, Pennsylvania, United States
, Nashville, Tennessee, United States
, Salt Lake, Utah, United States
Name: Denise A. Yardley, MD
Affiliation: Sara Cannon Research Institute
Role: PRINCIPAL_INVESTIGATOR