Spots Global Cancer Trial Database for A Study of Trastuzumab Emtansine (Kadcyla) Plus Pertuzumab (Perjeta) Following Anthracyclines in Comparison With Trastuzumab (Herceptin) Plus Pertuzumab and a Taxane Following Anthracyclines as Adjuvant Therapy in Participants With Operable HER2-Positive Primary Breast Cancer
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Trial Identification
Brief Title: A Study of Trastuzumab Emtansine (Kadcyla) Plus Pertuzumab (Perjeta) Following Anthracyclines in Comparison With Trastuzumab (Herceptin) Plus Pertuzumab and a Taxane Following Anthracyclines as Adjuvant Therapy in Participants With Operable HER2-Positive Primary Breast Cancer
Official Title: A Randomized, Multicenter, Open-Label, Phase III Trial Comparing Trastuzumab Plus Pertuzumab Plus a Taxane Following Anthracyclines Versus Trastuzumab Emtansine Plus Pertuzumab Following Anthracyclines as Adjuvant Therapy in Patients With Operable HER2-Positive Primary Breast Cancer
Study ID: NCT01966471
Conditions
Study Description
Brief Summary: This two-arm, randomized, open-label, multicenter study will evaluate the efficacy and safety of trastuzumab emtansine in combination with pertuzumab versus trastuzumab in combination with pertuzumab and a taxane as adjuvant therapy in participants with human epidermal growth (HER) factor 2 (HER2)-positive primary invasive breast cancer. Following surgery and anthracycline-based chemotherapy, participants will receive either trastuzumab emtansine at a dose of 3.6 milligrams per kilogram (mg/kg) and pertuzumab at a dose of 420 milligrams (mg) intravenously (IV) every 3 weeks (q3w) or trastuzumab at a dose of 6 mg/kg and pertuzumab at a dose of 420 mg IV q3w in combination with a taxane.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
HonorHealth Research Institute - Bisgrove, Scottsdale, Arizona, United States
Kaiser Permanente - Oakland, Oakland, California, United States
Kaiser Permanente - Roseville; Oncology Pharmacy, Roseville, California, United States
Kaiser Permanente - Sacramento; Oncology Pharmacy, Sacramento, California, United States
UC Davis Cancer Center; Oncology, Sacramento, California, United States
Southern California Kaiser Permanente, San Diego, California, United States
Kaiser Permanente - San Jose, San Jose, California, United States
Kaiser Permanente - San Leandro, San Leandro, California, United States
Kaiser Permanente - South SF; Oncology Clinical trials, South San Francisco, California, United States
Stanford University School of Medicine, Stanford, California, United States
Kaiser Permanente - Vallejo, Vallejo, California, United States
Kaiser Permanente - Walnut Creek; Oncology Pharmacy, Walnut Creek, California, United States
Holy Cross Hospital, Fort Lauderdale, Florida, United States
Florida Cancer Specialists; SCRI, Fort Myers, Florida, United States
Florida Cancer Specialists; Saint Petersburg, Saint Petersburg, Florida, United States
University Cancer & Blood Center, LLC; Research, Athens, Georgia, United States
Georgia Cancer Specialists, Atlanta, Georgia, United States
Central Georgia Cancer Care PC, Macon, Georgia, United States
Quincy Medical Group; Canc Ctr at Blessing Hosp, Quincy, Illinois, United States
Carle Cancer Center, Urbana, Illinois, United States
Indiana University, Indianapolis, Indiana, United States
Cancer Center of Kansas, Wichita, Kansas, United States
Anne Arundel Health System Research Instit-Annapolis Oncology Ctr, Annapolis, Maryland, United States
Mercy Medical Center, Baltimore, Maryland, United States
Dana Farber Cancer Inst., Boston, Massachusetts, United States
Beth Israel Deaconess Med Ctr, Boston, Massachusetts, United States
Karmanos Cancer Institute.., Detroit, Michigan, United States
Henry Ford Hospital; Hematology Oncology, Detroit, Michigan, United States
US oncology research at Minnesota Oncology, Saint Paul, Minnesota, United States
Mercy Medical Research Institute, Springfield, Missouri, United States
Dartmouth Hitchcock Med Center, Lebanon, New Hampshire, United States
Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, United States
Memorial Sloan-Kettering Cancer Center, Commack, New York, United States
ProHEALTH Care Associates LLP, Lake Success, New York, United States
Levine Cancer Institute, Charlotte, North Carolina, United States
Duke University Medical Center, Durham, North Carolina, United States
Cone Health Cancer Center, Greensboro, North Carolina, United States
Oncology Hematology Care Inc, Cincinnati, Ohio, United States
Mercy Clinic Oklahoma Communties, Inc, Oklahoma City, Oklahoma, United States
Magee-Woman's Hospital, Pittsburgh, Pennsylvania, United States
SCRI Tennessee Oncology Chattanooga, Chattanooga, Tennessee, United States
West Clinic, Germantown, Tennessee, United States
Thompson Cancer Survival Center, Knoxville, Tennessee, United States
Sarah Cannon Cancer Center - Tennessee Oncology, Pllc, Nashville, Tennessee, United States
The Center for Cancer and Blood Disorders - Fort Worth, Fort Worth, Texas, United States
Wellmont Medical Associates, Bristol, Virginia, United States
University of Virginia Health System; Hematology/Oncology Division, Charlottesville, Virginia, United States
Virginia Commonwealth University - Massey Cancer Center, Richmond, Virginia, United States
Blue Ridge Cancer Care - Salem, Salem, Virginia, United States
University of Washington, Seattle, Washington, United States
Chris O'Brien Lifehouse, Camperdown, New South Wales, Australia
Calvary Mater Newcastle; Medical Oncology, Waratah, New South Wales, Australia
Haematology & Oncology Clinics of Australia Research Centre, South Brisbane, Queensland, Australia
Burnside War Memorial Hospital, Clinical Trials Centre, Adelaide, South Australia, Australia
Frankston Hospital; Oncology/Haematology, Frankston, Victoria, Australia
Austin Hospital; Medical Oncology, Heidelberg, Victoria, Australia
Epworth HealthCare; Clinical Trials Centre, Richmond, Victoria, Australia
St John of God Murdoch Hospital; Oncology West, Murdoch, Western Australia, Australia
UZ Leuven Gasthuisberg, Leuven, , Belgium
Sint Augustinus Wilrijk, Apotheek, Wilrijk, , Belgium
University Clinical Center of the Republic of Srpska, Banja Luka, , Bosnia and Herzegovina
Clinic of Oncology, University Clinical Center Sarajevo, Sarajevo, , Bosnia and Herzegovina
Hospital Araujo Jorge; Departamento de Ginecologia E Mama, Goiania, GO, Brazil
Hospital Sao Lucas - PUCRS, Porto Alegre, RS, Brazil
Hospital Nossa Senhora da Conceicao, Porto Alegre, RS, Brazil
Hospital de Cancer de Barretos, Barretos, SP, Brazil
Instituto do Cancer do Estado de Sao Paulo - ICESP, Sao Paulo, SP, Brazil
Hospital Sirio Libanes; Centro de Oncologia, Sao Paulo, SP, Brazil
Hospital Perola Byington, Sao Paulo, SP, Brazil
Hospital Paulistano, Sao Paulo, SP, Brazil
Tom Baker Cancer Centre-Calgary, Calgary, Alberta, Canada
BC Cancer - Kelowna (Sindi Ahluwalia Hawkins Centre), Kelowna, British Columbia, Canada
Lions Gate Hospital, North Vancouver, British Columbia, Canada
BCCA-Vancouver Cancer Centre, Vancouver, British Columbia, Canada
Regional health authority A vitalite health network, Moncton, New Brunswick, Canada
Queen Elizabeth II Health Sciences Centre; Oncology, Halifax, Nova Scotia, Canada
Kingston General Hospital, Kingston, Ontario, Canada
London Regional Cancer Centre, London, Ontario, Canada
Credit Valley Hospital/Carlo Fidani Peel Regional Cancer Centre, Mississauga, Ontario, Canada
Southlake Regional Health Center; Community Care Clinic / Oncology, Newmarket, Ontario, Canada
Lakeridge Health Oshawa; Oncology, Oshawa, Ontario, Canada
Sault Area Hospital, Sault Ste. Marie, Ontario, Canada
North York General Hospital, Toronto, Ontario, Canada
Princess Margaret Cancer Center, Toronto, Ontario, Canada
Windsor Regional Cancer Centre, Windsor, Ontario, Canada
Cite de La Sante de Laval; Hemato-Oncologie, Laval, Quebec, Canada
McGill University; Glen Site; Oncology, Montreal, Quebec, Canada
Hopital du Saint Sacrement, Quebec City, Quebec, Canada
Instituto Oncologico del sur, Temuco, , Chile
ONCOCENTRO APYS; Oncología, Vina Del Mar, , Chile
Oncomedica S.A., Monteria, , Colombia
Masarykuv onkologicky ustav, Brno, , Czechia
Fakultni Nemocnice Hradec Kralove; Dept of Radiotherapy & Oncology, Hradec Kralove, , Czechia
MULTISCAN, s.r.o., Radiologicke centrum Pardubice, Pardubice, , Czechia
Vseobecna fakultni nemocnice v Praze, Praha 2, , Czechia
Hospital Diagnostico Escalón, San Salvador, , El Salvador
Ico - Paul Papin, Angers, , France
Clinique Sainte Catherine, Avignon, , France
HOPITAL JEAN MINJOZ; Oncologie, Besancon, , France
Institut Bergonie; Oncologie, Bordeaux, , France
CHU de Brest - Hôpital de Morvan, Brest, , France
Centre Francois Baclesse; Oncologie, Caen, , France
Centre Jean Perrin; Oncologie, Clermont Ferrand, , France
Centre Georges Francois Leclerc; Oncologie 3, Dijon, , France
Clinique Victor Hugo; Chimiotherapie, Le Mans, , France
Centre Oscar Lambret; Cancerologie Gynecologique, Lille, , France
Centre Leon Berard; Departement Oncologie Medicale, Lyon, , France
Centre D'Oncologie de Gentilly; Oncology, Nancy, , France
Centre Antoine Lacassagne, Nice, , France
Institut de cancerologie du Gard, Nimes, , France
HOPITAL TENON; Cancerologie Medicale, Paris, , France
Centre Armoricain de Radiotherapie, de Imagerie Medicale et de Oncologie (CARIO), Plerin, , France
Polyclinique De Courlancy; Centre Radiotherapie Oncologie, Reims, , France
Centre Eugene Marquis; Service d'oncologie, Rennes, , France
Ico Rene Gauducheau; Oncologie, Saint Herblain, , France
Institut De Cancerologie De La Loire; Consult Oncologie Niveau 0, St Priest En Jarez, , France
Institut d'oncologie de l'Orangerie; Chimiotherapie, Strasbourg, , France
Centre Paul Strauss; Oncologie Medicale, Strasbourg, , France
Institut Claudius Regaud; Departement Oncologie Medicale, Toulouse, , France
Centre Alexis Vautrin; Oncologie Medicale, Vandoeuvre-les-nancy, , France
LTD Institute of Clinical Oncology, Tbilisi, , Georgia
Khechinashvili University Hospital ;Breast Unit, Tbilisi, , Georgia
Chemotherapy and Immunotherapy Clinic Medulla, Tbilisi, , Georgia
Klinikum Augsburg, Augsburg, , Germany
Hochwaldkrankenhaus, Bad Nauheim, , Germany
Frauenarzt-Zentrum Zehlendorf an der Teltower Eiche, Berlin, , Germany
Gemeinschaftspraxis Dr. Bueckner und Dr. Nueckel, Bochum, , Germany
BAG Freiberg-Richter, Jacobasch, Illmer, Wolf; Gemeinschaftspraxis Hämatologie-Onkologie, Dresden, , Germany
AGAPLESION Markus-Krankenhaus, Frankfurt, , Germany
Städtische Kliniken Frankfurt am Main Höchst, Frankfurt, , Germany
Praxis für Interdisziplinäre Onkologie und Hämatologie GbR, Freiburg, , Germany
Dres.Jochen Wilke und Harald Wagner, Fürth, , Germany
Niels-Stensen-Kliniken Franziskus-Hospital Harderberg GmbH, Georgsmarienhütte, , Germany
Universitätsklinikum Hamburg-Eppendorf; Frauenklinik, Hamburg, , Germany
Gynaekologisch-Onkologische Schwerpunktpraxis Prof. Dr. med. Lueck, Dr. Schrader und Dr. Noeding, Hannover, , Germany
Medizinische Hochschule Hannover, Klinik für Frauenheilkunde und Geburtshilfe, Hannover, , Germany
Klinikum Kulmbach; Frauenklinik, Kulmbach, , Germany
Praxis Dr.med. Katja Ziegler-Löhr, Köln, , Germany
Universitätsklinikum Schleswig-Holstein / Campus Lübeck; Klinik für Frauenheilkunde und Geburtshilfe, Lübeck, , Germany
Klinikum Meiningen Klinik f.Gynäkologie und Geburtshilfe, Meiningen, , Germany
Klinikum der Universität München; Campus Großhadern; Klinik und Poliklinik für Frauenheilkunde, Muenchen, , Germany
Hämatologisch/Onkologische Praxis Prof. Dr. Decker, Studienzentrum, Ravensburg, , Germany
Agaplesion Diakonieklinikum Rotenburg, Rotenburg/Wümme, , Germany
Gynäkologie Kompetenzzentrum; Praxis Dr. med. Carsten Hielscher, Stralsund, , Germany
Dres. Helmut Forstbauer, Carsten Ziske und Kollegen; Onkologische Schwerpunktpraxis, Troisdorf, , Germany
GRN-Klinik Weinheim; Abt.Gynäkologie und Geburtshilfe, Weinheim, , Germany
Klinikum Worms; Frauenklinik; Klinik für Gynäkologie und Geburtshilfe, Worms, , Germany
Grupo Angeles, Guatemala City, , Guatemala
Centro Oncológico Sixtino / Centro Oncológico SA, Guatemala, , Guatemala
Princess Margaret Hospital; Oncology, Hong Kong, , Hong Kong
Tuen Mun Hospital; Clinical Oncology, Hong Kong, , Hong Kong
Queen Mary Hospital; Dept of Surgery, Pokfulam, , Hong Kong
Orszagos Onkologiai Intezet; B Belgyogyaszati Osztaly, Budapest, , Hungary
Municipal Hospital of Uzsoki Utca; Centre of Oncoradiology, Budapest, , Hungary
Debreceni Egyetem, Klinikai Kozpont, Onkologiai Klinika, Debrecen, , Hungary
Szegedi Tudomanyegyetem, AOK, Szent-Gyorgyi Albert Klinikai Kozpont, Onkoterapias Klinika, Szeged, , Hungary
Chaim Sheba Medical Center; Oncology Dept, Ramat Gan, , Israel
Sourasky / Ichilov Hospital; Oncology Department, Tel Aviv, , Israel
Istituto Nazionale Tumori Fondazione G. Pascale, Napoli, Campania, Italy
Azienda Ospedaliero-Universitaria S.Orsola-Malpighi; Unità Operativa Oncologia Medica, Bologna, Emilia-Romagna, Italy
Irccs Centro Di Riferimento Oncologico (CRO); Dipartimento Di Oncologia Medica, Aviano, Friuli-Venezia Giulia, Italy
Policlinico Universitario Campus Biomedico; Uoc Oncologia Medica, Roma, Lazio, Italy
Istituto Nazionale Tumori Regina Elena IRCCS, Roma, Lazio, Italy
ASST DI CREMONA; Unità di Patologia Mammaria Senologia e Breast Unit, Cremona, Lombardia, Italy
Ospedale San Raffaele, Milano, Lombardia, Italy
Irccs Istituto Nazionale Dei Tumori (Int);S.C. Medicina Oncologica 1, Milano, Lombardia, Italy
ASST DI MONZA; Oncologia Medica, Monza, Lombardia, Italy
Istituto Clinico Humanitas;U.O. Oncologia Medica Ed Ematologia, Rozzano, Lombardia, Italy
Ospedale Antonio Perrino; Oncologia Medica, Brindisi, Puglia, Italy
Humanitas Centro Catanese Di Oncologia; Oncologia Medica, Misterbianco (CT), Sicilia, Italy
Ospedale Misericordia E Dolce; Oncologia Medica, Prato, Toscana, Italy
Azienda Ospedaliera S. Maria - Terni; Oncologia, Terni, Umbria, Italy
IOV - Istituto Oncologico Veneto - IRCCS; Oncologia Medica II, Padova, Veneto, Italy
Aichi Cancer Center Hospital, Breast Oncology, Aichi, , Japan
Nagoya City University Hospital; Breast Surgery, Aichi, , Japan
Natl Hosp Org Shikoku; Cancer Ctr, Surgery, Ehime, , Japan
National Hospital Organization Kyushu Cancer Center;Breast Oncology, Fukuoka, , Japan
Gunma University Hospital; Department of Breast and Endocrine Surgery, Gunma, , Japan
Gunma Prefectural Cancer Center; Breast Oncology, Gunma, , Japan
Hiroshima City Hiroshima Citizens Hospital; Breast Surgery, Hiroshima, , Japan
Hiroshima University Hospital; Breast Surgery, Hiroshima, , Japan
Hyogo College Of Medicine; Breast And Endocrine Surgery, Hyogo, , Japan
Iwate Med Univ School of Med; Surgery, Iwate, , Japan
Sagara Hospital; Breast Surgery, Kagoshima, , Japan
St. Marianna University School of Medicine Hospital, Breast and Endocrine Surgery, Kanagawa, , Japan
Tokai University Hospital, Breast Surgery, Kanagawa, , Japan
Kumamoto City Hospital, Breast and Endocrine Surgery, Kumamoto, , Japan
Kumamoto Shinto General Hospital; Breast Cancer Center, Kumamoto, , Japan
Kyoto University Hospital; Breast Surgery, Kyoto, , Japan
Niigata Cancer Ctr Hospital; Breast Surgery, Niigata, , Japan
Kawasaki Medical School Hospital; Breast and Thyroid Surgery, Okayama, , Japan
Naha-nishi Clinic; Surgery, Okinawa, , Japan
National Hospital Organization Osaka National Hospital; Breast Surgery, Osaka, , Japan
Osaka International Cancer Institute; Breast and Endocrine Surgery, Osaka, , Japan
Saitama Medical University International Medical Center; Breast Oncology, Saitama, , Japan
Saitama Cancer Center, Breast Oncology, Saitama, , Japan
Shizuoka Cancer Center; Breast Surgery, Shizuoka, , Japan
Shizuoka General Hospital; Breast Surgery, Shizuoka, , Japan
Jichi Medical University; Breast Oncology, Tochigi, , Japan
National Cancer Center Hospital; Medical Oncology, Tokyo, , Japan
St. Luke's Internat. Hospital, Breast Surgical Oncology, Tokyo, , Japan
Tokyo Metropolitan; Komagome Hospital, Surgery, Tokyo, , Japan
The Cancer Inst. Hosp. of JFCR; Breast Oncology Center, Tokyo, , Japan
Showa University Hospital; Breast Surgery, Tokyo, , Japan
Tokyo Medical Uni. Hospital; Breast Oncology, Tokyo, , Japan
National Cancer Center; Medical Oncology, Gyeonggi-do, , Korea, Republic of
Ajou Uni Hospital; Medical Oncology, Gyeonggi-do, , Korea, Republic of
Seoul National Uni Hospital; Dept. of Internal Medicine/Hematology/Oncology, Seoul, , Korea, Republic of
Severance Hospital, Yonsei University Health System, Seoul, , Korea, Republic of
Samsung Medical Centre; Division of Hematology/Oncology, Seoul, , Korea, Republic of
Instituto Nacional De Cancerologia; Oncology; Tumores Mamarios, Distrito Federal, , Mexico
Fundacion Rodolfo Padilla Padilla A.C., León, , Mexico
Consultorio de Medicina Especializada; Dentro de Condominio San Francisco, Mexico City, , Mexico
Hospital San Jose Del Tec. de Monterrey; Oncology, Monterrey, , Mexico
Oslo universitetssykehus HF, Ullevål, Kreftsenteret, Oslo, , Norway
Helse Stavanger HF, Stavanger Universitetssjukehus; Klinikk for Blod og kreftsykdommer, Stavanger, , Norway
Centro Hemato Oncologico Panama, Panama, , Panama
Clinica de Especialidades Medicas, Lima, , Peru
Clinica Internacional, Sede San Borja; Unidad de Investigacion de Clínica Internacional, Lima, , Peru
Clinica San Borja, Lima, , Peru
Instituto Oncologico Miraflore, Miraflores, , Peru
San Juan de Dios Hospital;Oncology Unit, Pasay, , Philippines
East Avenue Medical Center, Quezon City, , Philippines
Bialostockie Centrum Onkologii; Oddzial Onkologii Klinicznej, Bialystok, , Poland
Centrum Onkologii;Im. Franciszka Lukaszczyka;Onkologii, Bydgoszcz, , Poland
Uniwersyteckie Centrum Kliniczne, Klinika Onkologii i Radioterapii, Gdansk, , Poland
Szpital Uniwersytecki w Krakowie, Oddział Kliniczny Kliniki Onkologii, Kraków, , Poland
Wojewodzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii; Poradnia Chemioterapii, Lodz, , Poland
Centrum Onkologii Ziemi LUBELSKIEJ im. Sw Jana z Dukli, I oddz. Chemioterapii, Lublin, , Poland
Europejskie Centrum Zdrowia Otwock Szpital im. Fryderyka Chopina, Klinika Onkologii, Otwock, , Poland
Narodowy Inst.Onkologii im.Sklodowskiej-Curie Panstw.Inst.Bad; Klinika Nowtw.Piersi i Chir.Rekonstr, Warszawa, , Poland
Institutul Oncologic Prof. Dr. Al. Trestioreanu Bucuresti, Bucuresti, , Romania
Prof. Dr. I. Chiricuta Institute of Oncology, Cluj Napoca, , Romania
Cluj Clinical County Hospital; Oncology Dept, Cluj-Napoca, , Romania
Regional Institute of Oncology Iasi, Iasi, , Romania
Ivanovo Regional Oncology Dispensary, Ivanovo, , Russian Federation
Republican Clinical Oncologic Dispensary of Republic Of Tatarstan, Kazan, , Russian Federation
FSBI Russian Oncology Research Center n.a. Blokhin of MOH RF, Moscow, , Russian Federation
State Inst. Of Healthcare Orenburg Regional Clinical Oncology Dis, Orenburg, , Russian Federation
SBI for HPE "Ryazan State Medical University n.a. I.P. Pavlov" of MoH of RF, Ryazan, , Russian Federation
Scientific Research Institute n.a. N.N. Petrov, Saint Petersburg, , Russian Federation
SBI of Healthcare Samara Regional Clinical Oncology Dispensary, Samara, , Russian Federation
National University Hospital; National University Cancer Institute, Singapore (NCIS), Singapore, , Singapore
National Cancer Centre; Medical Oncology, Singapore, , Singapore
Hospital Universitario de Canarias;servicio de Oncologia, La Laguna, Tenerife, Spain
Hospital de Cruces; Servicio de Oncologia, Bilbao, Vizcaya, Spain
Hospital del Mar; Servicio de Oncologia, Barcelona, , Spain
Hospital Univ Vall d'Hebron; Servicio de Oncologia, Barcelona, , Spain
Hospital Duran i Reynals; Oncologia, Barcelona, , Spain
Hospital General Universitario Gregorio Marañon; Servicio de Oncologia, Madrid, , Spain
Centro Oncologico MD Anderson Internacional; Servicio de Oncologia, Madrid, , Spain
Hospital Clinico Universitario Virgen de la Victoria; Servicio de Oncologia, Malaga, , Spain
Hospital Universitario Virgen de Arrixaca; Servicio de Oncologia, Murcia, , Spain
Hospital Clínico Universitario de Valencia; Servicio de Oncología, Valencia, , Spain
Hospital Universitario Miguel Servet; Servicio Oncologia, Zaragoza, , Spain
Sahlgrenska Universitetssjukhuset; Jubileumskliniken, Göteborg, , Sweden
Akademiska sjukhuset, Onkologkliniken, Uppsala, , Sweden
Universitetssjukhuset Örebro, Onkologiska kliniken, Örebro, , Sweden
Kantonsspital Graubünden Medizin Onkologie; Onkologie und Hämatologie, Chur, , Switzerland
Luzerner Kantonsspital; Medizinische Onkologie, Luzern, , Switzerland
Brust-Zentrum Zürich AG Seefeldstrasse 214 Zürich, Zürich, , Switzerland
Changhua Christian Hospital; Dept of Surgery, Changhua, , Taiwan
Kaohsiung Medical Uni Chung-Ho Hospital; Dept of Surgery, Kaohsiung, , Taiwan
Taichung Veterans General Hospital; Dept of Surgery, Taichung, , Taiwan
VETERANS GENERAL HOSPITAL; Department of General Surgery, Taipei, , Taiwan
National Taiwan Uni Hospital; General Surgery, Taipei, , Taiwan
Tri-Service General Hospital, Division of General Surgery, Taipei, , Taiwan
Chulalongkorn Hospital; Medical Oncology, Bangkok, , Thailand
Faculty of Med. Siriraj Hosp.; Med.-Div. of Med. Oncology, Bangkok, , Thailand
Chiang Rai Prachanukroh Hospital; Department Of Medicine, Chiang Rai, , Thailand
Buddhachinaraj Phitsanulok Hospital; Chemotherapy Unit ; Department of Medicine, Phitsanuok, , Thailand
State Medical Academy; Oncology, Dnipropetrovsk, , Ukraine
Lviv State Oncological Regional Treatment and Diagnostic Center, Lviv, , Ukraine
Velindre Cancer Centre; Oncology Dept, Cardiff, , United Kingdom
Cheltenham General Hospital; Gloucestershire Oncology Centre, Cheltenham, , United Kingdom
Royal Cornwall Hospital; Dept of Clinical Oncology, Cornwall, , United Kingdom
University Hospital Coventry; InHANSE Unit and Clinical Trials Cancer Treatment Centre, Coventry, , United Kingdom
Western General Hospital; Edinburgh Breast Unit, Edinburgh, , United Kingdom
Royal Devon & Exeter Hospital; Oncology Centre, Exeter, , United Kingdom
Royal Surrey County Hospital; St. Lukes Cancer Centre, Guildford, , United Kingdom
Leicester Royal Infirmary; Dept. of Medical Oncology, Leicester, , United Kingdom
Royal Marsden Hospital - Fulham; Oncology Department, London, , United Kingdom
Charing Cross Hospital, London, , United Kingdom
Maidstone Hospital; Kent Oncology Centre, Maidstone, , United Kingdom
Christie Hospital; Breast Cancer Research Office, Manchester, , United Kingdom
Freeman Hospital; Northern Centre For Cancer Care, New Castle Upon Tyne, , United Kingdom
Mount Vernon Cancer Centre, Northwood, , United Kingdom
Nottingham City Hospital; Oncology, Nottingham, , United Kingdom
Peterborough City Hospital, Edith Cavell Campus; Oncology Department, Peterborough, , United Kingdom
Queen Alexandra Hospital; Portsmouth Haematology & Oncology Centre, Level B, Portsmouth, , United Kingdom
Weston Park Hospital; Cancer Clinical Trials Centre, Sheffield, , United Kingdom
Musgrove Park Hospital; Department Clinical Research, Beacon Centre, Somerset, , United Kingdom
Uni Hospital of North Staffordshire; Staffordshire Oncology Centre, Stoke-on-Trent, , United Kingdom
Royal Marsden Hospital; Dept of Medical Oncology, Sutton, , United Kingdom
Yeovil District Hospital; Macmillan Cancer Unit, Yeovil, , United Kingdom
Contact Details
Name: Clinical Trials
Affiliation: Hoffmann-La Roche
Role: STUDY_DIRECTOR
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