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Brief Title: Taking AIM at Breast Cancer
Official Title: Taking AIM at Breast Cancer: Targeting Adiposity and Inflammation With Movement to Improve Prognosis in Breast Cancer Survivors
Study ID: NCT04720209
Brief Summary: The purpose of this research is to determine whether a 16-week exercise program for individuals with breast cancer and have completed treatment (i.e., surgery, chemotherapy, or radiation) for breast cancer will decrease inflammation in fat tissue.
Detailed Description: This study is about using different types of exercise to reduce inflammation in fat tissue in an effort to minimize the risk of cancer recurrence related to being overweight or obese. The investigators hope to learn whether participating in a specific exercise program can cause inflammation in the fat tissue to decrease. The names of the study interventions involved in this study are: * Circuit-style aerobic and resistance exercise (CARE) * Traditional aerobic and resistance exercise (TARE) The research study procedures include screening for eligibility, and study treatment including evaluations and follow up visits. The study treatment will be for 4 months and participants will followed for 8 months. The total time for participation in this study will be about 12 months. It is expected that about 300 people will take part in this research study.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Brigham and Women's Hospital, Boston, Massachusetts, United States
Dana Farber Cancer Institute, Boston, Massachusetts, United States
Name: Christina M Dieli-Conwright, PhD
Affiliation: Dana-Farber Cancer Institute
Role: PRINCIPAL_INVESTIGATOR