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Brief Title: Study of Stereotactic Radiotherapy for Breast Cancer
Official Title: A Phase II Study of Preoperative Single Fraction Stereotactic Body Radiotherapy to the Intact Breast in Early Stage Low Risk Breast Cancer: Analysis of Radiation Response
Study ID: NCT03043794
Brief Summary: This is a Phase II trial of preoperative stereotactic radiation to the breast for low risk breast cancer.
Detailed Description: This is a single arm phase II study design, evaluating the pathologic response (primary endpoint) as well as toxicity, cosmetic outcome, quality of life, and translational correlates (secondary endpoints) to pre-operative stereotactic body radiotherapy (SBRT) to intact breast tumors in patients with hormone-receptor positive early stage breast cancer.
Minimum Age: 50 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Sibley Memorial Hospital, Washington, District of Columbia, United States
Johns Hopkins Hospital, Baltimore, Maryland, United States
Name: Jean Wright, MD
Affiliation: Johns Hopkins University
Role: PRINCIPAL_INVESTIGATOR