Spots Global Cancer Trial Database for Molecular Mechanisms of Clinical Resistance to Targeted Therapy Among Patients With Breast Cancer
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Trial Identification
Brief Title: Molecular Mechanisms of Clinical Resistance to Targeted Therapy Among Patients With Breast Cancer
Official Title: Molecular Mechanisms of Clinical Resistance to Targeted Therapy Among Patients With Breast Cancer
Study ID: NCT00897702
Conditions
Study Description
Brief Summary: The purpose of this study is to learn why certain drugs stop working in patients.In lab studies, tumors become resistant in several ways. Specific molecules seem to change and this may be why therapy stops working. However, we do not know if the same molecules change in patients. This study is being done to see if they do change. If we learn more about how patients become resistant, we may be able to offer better treatment in the future.
Detailed Description:
Eligibility
Minimum Age:
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Memorial Sloan Kettering Basking Ridge (Consent only), Basking Ridge, New Jersey, United States
Memorial Sloan Kettering Monmouth (Consent only), Middletown, New Jersey, United States
Memorial Sloan Kettering Bergen (Consent only), Montvale, New Jersey, United States
Memorial Sloan Kettering Commack (Consent only), Commack, New York, United States
Memorial Sloan Kettering Westchester (Consent only), Harrison, New York, United States
Memorial Sloan Kettering Cancer Center, New York, New York, United States
Memorial Sloan Kettering Nassau (Consent only), Uniondale, New York, United States
Contact Details
Name: Sarat Chandarlapaty, MD, PhD
Affiliation: Memorial Sloan Kettering Cancer Center
Role: STUDY_CHAIR
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