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Spots Global Cancer Trial Database for Comparison Trial of Letrozole to Anastrozole in the Adjuvant Treatment of Postmenopausal Women With Hormone Receptor and Node Positive Breast Cancer

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Trial Identification

Brief Title: Comparison Trial of Letrozole to Anastrozole in the Adjuvant Treatment of Postmenopausal Women With Hormone Receptor and Node Positive Breast Cancer

Official Title: Comparison Trial of Letrozole to Anastrozole in the Adjuvant Treatment of Postmenopausal Women With Hormone Receptor and Node Positive Breast Cancer

Study ID: NCT00248170

Conditions

Breast Cancer

Study Description

Brief Summary: Eligible patients will be post-menopausal hormone receptor- and lymph node-positive females who recently underwent primary surgery for breast cancer. Patients will be randomized to letrozole (2.5 mg per day for 5 years) vs anastrozole (1 mg per day for 5 years). Follow up will occur for 5 years after the completion of enrollment for survival and disease status updates.

Detailed Description:

Eligibility

Minimum Age: 33 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: FEMALE

Healthy Volunteers: No

Locations

Birmingham Hematology and Oncology Associates, Birmingham, Alabama, United States

Comprehensive Cancer Institute, Huntsville, Alabama, United States

Northern Arizona Hematology/Oncology Associates, P.C., Flagstaff, Arizona, United States

Oncology & Hematology Associates, PC, New London, Connecticut, United States

Florida Cancer Specialists, Fort Meyers, Florida, United States

Sarah Cannon Research Institute, Jacksonville, Florida, United States

Cancer Centers of Florida PA, Ocoee, Florida, United States

Florida Cancer Institute, Orlando, Florida, United States

Gulfcoast Oncology Associates, St. Petersburg, Florida, United States

University Cancer & Blood Center, LLC, Athens, Georgia, United States

Central Indiana Cancer Centers, Indianapolis, Indiana, United States

Kansas City Cancer Center, Overland Park, Kansas, United States

Wichita Community Clinical Oncology Program, Wichita, Kansas, United States

Center for Cancer & Blood Disorders, Bethesda, Maryland, United States

St. Louis Cancer & Breast Institute, St. Louis, Missouri, United States

New York Oncology Hematology, P.C. NYOH Latham, Troy, New York, United States

Raleigh Hematology Oncology Associates, Cary, North Carolina, United States

Aultman Cancer Center, Canton, Ohio, United States

Sarah Cannon Oncology Hematology Care, Inc, Cincinnati, Ohio, United States

Oncology Associates of Oregon, PC, Eugene, Oregon, United States

Medical Oncology Associates of Wyorning Valley, PC, Kingston, Pennsylvania, United States

Chattanooga Oncology and Hematology Assoicates, PC, Chattanooga, Tennessee, United States

Sarah Cannon Research Institute, Nashville, Tennessee, United States

Texas Oncology, P.A., Bedford, Texas, United States

Center for Oncology Research and Treatment, PA, Dallas, Texas, United States

Texas Cancer Center ( Medical City Dallas Hospital), Dallas, Texas, United States

Texas Oncology Presbyterian Hospital, Dallas, Texas, United States

Texas Oncology Sammons Cancer Center, Dallas, Texas, United States

Texas Oncology Texas Oncology PA, Dallas, Texas, United States

Texas Cancer Center Denton, Denton, Texas, United States

El Paso Cancer Treatment Ctr-East, El Paso, Texas, United States

Texas Oncology, P.A., Fort Worth, Texas, United States

San Antonio Tumor and Blood Clinic, Fredericksburg, Texas, United States

MD Anderson Cancer Center/University of Texas, Houston, Texas, United States

Longview Cancer Center, Longview, Texas, United States

South Texas Cancer Center- McAllen, McAllen, Texas, United States

Allison Cancer Center, Midland, Texas, United States

Texas Cancer Center- Sherman, Sherman, Texas, United States

Tyler Cancer Center, Tyler, Texas, United States

Waco Cancer and Research Center, Waco, Texas, United States

Virginia Cancer Specialists, PC, Fairfax, Virginia, United States

Northwest Cancer Specialists, P.C., Vancover, Washington, United States

Novartis Investigative Site, Garran, Australian Capital Territory, Australia

Novartis Investigative Site, Port Macquarie, New South Wales, Australia

Novartis Investigative Site, Randwick, New South Wales, Australia

Novartis Investigative Site, Sydney, New South Wales, Australia

Novartis Investigative Site, Tweed Heads, New South Wales, Australia

Novartis Investigative Site, Waratah, New South Wales, Australia

Novartis Investigative Site, Nambour, Queensland, Australia

Novartis Investigative Site, Redcliff, Queensland, Australia

Novartis Investigative Site, Adelaide, South Australia, Australia

Novartis Investigative Site, Toorak Gardens, South Australia, Australia

Novartis Investigative Site, Box Hill, Victoria, Australia

Novartis Investigative Site, East Bentleigh, Victoria, Australia

Novartis Investigative Site, Epping, Victoria, Australia

Novartis Investigative Site, Footscray, Victoria, Australia

Novartis Investigative Site, Franston, Victoria, Australia

Novartis Investigative Site, Malvern, Victoria, Australia

Novartis Investigative Site, Parkville, Victoria, Australia

Novartis Investigative Site, Wodonga, Victoria, Australia

Novartis Investigative Site, Nedlands, Western Australia, Australia

Novartis Investigative Site, Perth, Western Australia, Australia

Novartis Investigative Site, Perth, Western Australia, Australia

Novartis Investigative Site, Auckland, , Australia

Novartis Investigative Site, Dunedin, , Australia

Novartis Investigative Site, Hamilton, , Australia

Novartis Investigative Site, Feldkirch, , Austria

Novartis Investigative Site, Friesach, , Austria

Novartis Investigative Site, Graz, , Austria

Novartis Investigative Site, Graz, , Austria

Novartis Investigative Site, Güssing, , Austria

Novartis Investigative Site, Innsbruck, , Austria

Novartis Investigative Site, Leoben, , Austria

Novartis Investigative Site, Linz, , Austria

Novartis Investigative Site, Linz, , Austria

Novartis Investigative Site, Salzburg, , Austria

Novartis Investigative Site, Vienna, , Austria

Novartis Investigative Site, Villach, , Austria

Novartis Investigative Site, Wels, , Austria

Novartis Investigative Site, Wiener Neustadt, , Austria

Novartis Investigative Site, Wien, , Austria

Novartis Investigative Site, Wien, , Austria

Novartis Investigative Site, Aalst, , Belgium

Novartis Investigative Site, Antwerpen, , Belgium

Novartis Investigative Site, Bonheiden, , Belgium

Novartis Investigative Site, Brasschaat, , Belgium

Novartis Investigative Site, Brugge, , Belgium

Novartis Investigative Site, Bruxelles, , Belgium

Novartis Investigative Site, Gent, , Belgium

Novartis Investigative Site, Libramont, , Belgium

Novartis Investigative Site, Liege, , Belgium

Novartis Investigative Site, Liège, , Belgium

Novartis Investigative Site, Turnhout, , Belgium

Novartis Investigative Site, Verviers, , Belgium

Novartis Investigative Site, Wilrijk, , Belgium

Novartis Investigative Site, Newmarket, Ontario, Canada

Novartis Investigative Site, Ottawa, Ontario, Canada

Novartis Investigative Site, Toronto, Ontario, Canada

Novartis Investigative Site, Toronto, Ontario, Canada

Novartis Investigative Site, Montreal, Quebec, Canada

Novartis Investigative Site, Regina, Saskatchewan, Canada

Novartis Investigative Site, Saskatoon, Saskatchewan, Canada

Novartis Investigative Site, Quebec, , Canada

Novartis Investigative Site, Tianjin, Tianjin, China

Novartis Investigative Site, Beijing, , China

Novartis Investigative Site, Guangzhou, , China

Novartis Investigative Site, Shanghai, , China

Novartis Investigative Site, Aalborg, , Denmark

Novartis Investigative Site, Copenhagen, , Denmark

Novartis Investigative Site, Herlev, , Denmark

Novartis Investigative Site, Herning, , Denmark

Novartis Investigative Site, Hillerød, , Denmark

Novartis Investigative Site, Næstved, , Denmark

Novartis Investigative Site, Odense C, , Denmark

Novartis Investigative Site, Roskilde, , Denmark

Novartis Investigative Site, Vejle, , Denmark

Novartis Investigative Site, Viborg, , Denmark

Novartis Investigative Site, Angers cedex 9, , France

Novartis Investigative Site, Caen Cedex, , France

Novartis Investigative Site, Creteil, , France

Novartis Investigative Site, Le Chesnay, , France

Novartis Investigative Site, Lyon, , France

Novartis Investigative Site, Marseille, , France

Novartis Investigative Site, Montbeliard, , France

Novartis Investigative Site, Montpellier, , France

Novartis Investigative Site, Nice, , France

Novartis Investigative Site, Perpignan, , France

Novartis Investigative Site, Périgueux Cédex, , France

Novartis Investigative Site, Rennes Cedex, , France

Novartis Investigative Site, Strasbourg, , France

Novartis Investigative Site, Toulouse Cedex, , France

Novartis Investigative Site, Amberg, , Germany

Novartis Investigative Site, Bayreuth, , Germany

Novartis Investigative Site, Berlin, , Germany

Novartis Investigative Site, Berlin, , Germany

Novartis Investigative Site, Berlin, , Germany

Novartis Investigative Site, Berlin, , Germany

Novartis Investigative Site, Berlin, , Germany

Novartis Investigative Site, Berlin, , Germany

Novartis Investigative Site, Bremen, , Germany

Novartis Investigative Site, Duesseldorf, , Germany

Novartis Investigative Site, Erlangen, , Germany

Novartis Investigative Site, Essen, , Germany

Novartis Investigative Site, Frankfurt, , Germany

Novartis Investigative Site, Freiburg, , Germany

Novartis Investigative Site, Freiburg, , Germany

Novartis Investigative Site, Halle/'Saale, , Germany

Novartis Investigative Site, Hannover, , Germany

Novartis Investigative Site, Hannover, , Germany

Novartis Investigative Site, Homburg, , Germany

Novartis Investigative Site, Jena, , Germany

Novartis Investigative Site, Kiel, , Germany

Novartis Investigative Site, Lübeck, , Germany

Novartis Investigative Site, Lüneburg, , Germany

Novartis Investigative Site, Magdeburg, , Germany

Novartis Investigative Site, Muenchen, , Germany

Novartis Investigative Site, Muenster, , Germany

Novartis Investigative Site, München, , Germany

Novartis Investigative Site, Offenbach, , Germany

Novartis Investigative Site, Regensburg, , Germany

Novartis Investigative Site, Trier, , Germany

Novartis Investigative Site, Tuebingen, , Germany

Novartis Investigative Site, Ulm, , Germany

Novartis Investigative Site, Wiesbaden, , Germany

Novartis Investigative Site, Wiesbaden, , Germany

Novartis Investigative Site, Witten, , Germany

Novartis Investigative Site, Cork, , Ireland

Novartis Investigative Site, Dublin 24, , Ireland

Novartis Investigative Site, Dublin 4, , Ireland

Novartis Investigative Site, Dublin 7, , Ireland

Novartis Investigative Site, Dublin 8, , Ireland

Novartis Investigative Site, Dublin, , Ireland

Novartis Investigative Site, Galway, , Ireland

Novartis Investigative Site, Letterkenny, , Ireland

Novartis Investigative Site, Limerick, , Ireland

Novartis Investigative Site, Jerusalem, , Israel

Novartis Investigative Site, Rehovot, , Israel

Novartis Investigative Site, Tel-Aviv, , Israel

Novartis Investigative Site, Tel-Hashomer, , Israel

Novartis Investigative Site, Montevarchi, AR, Italy

Novartis Investigative Site, Bari, BA, Italy

Novartis Investigative Site, Biella, BI, Italy

Novartis Investigative Site, Bologna, BO, Italy

Novartis Investigative Site, Chieti, CH, Italy

Novartis Investigative Site, Catania, CT, Italy

Novartis Investigative Site, Antella - Bagno a Ripoli, FI, Italy

Novartis Investigative Site, Forli, FO, Italy

Novartis Investigative Site, Milano, MI, Italy

Novartis Investigative Site, Milano, MI, Italy

Novartis Investigative Site, Modena, MO, Italy

Novartis Investigative Site, Aviano, PN, Italy

Novartis Investigative Site, Parma, PR, Italy

Novartis Investigative Site, Roma, RM, Italy

Novartis Investigative Site, Roma, RM, Italy

Novartis Investigative Site, Roma, RM, Italy

Novartis Investigative Site, Castelfranco Veneto, TV, Italy

Novartis Investigative Site, Udine, UD, Italy

Novartis Investigative Site, Verona, VR, Italy

Novartis Investigative Site, Fermo, , Italy

Novartis Investigative Site, Nagoya, Aichi, Japan

Novartis Investigative Site, Matsuyama, Ehime, Japan

Novartis Investigative Site, Kitakyushu, Fukuoka, Japan

Novartis Investigative Site, Maebashi-city, Gunma, Japan

Novartis Investigative Site, Sapporo, Hokkaido, Japan

Novartis Investigative Site, Isehara-city, Kanagawa, Japan

Novartis Investigative Site, Kawasaki-city, Kanagawa, Japan

Novartis Investigative Site, Yokohama, Kanagawa, Japan

Novartis Investigative Site, Kyoto-city, Kyoto, Japan

Novartis Investigative Site, Suita-city, Osaka, Japan

Novartis Investigative Site, Kitaadachi-gun, Saitama, Japan

Novartis Investigative Site, Shimotsuke-city, Tochigi, Japan

Novartis Investigative Site, Bunkyo-ku, Tokyo, Japan

Novartis Investigative Site, Chuo-ku, Tokyo, Japan

Novartis Investigative Site, Chuo-ku, Tokyo, Japan

Novartis Investigative Site, Koto, Tokyo, Japan

Novartis Investigative Site, Shinjuku-ku, Tokyo, Japan

Novartis Investigative Site, Fukuoka, , Japan

Novartis Investigative Site, Osaka, , Japan

Novartis Investigative Site, Shizuoka, , Japan

Novartis Investigative Site, Goyang, Gyeonggi-do, Korea, Republic of

Novartis Investigative Site, Seoul, Korea, Korea, Republic of

Novartis Investigative Site, Seoul, , Korea, Republic of

Novartis Investigative Site, Eindhoven, , Netherlands

Novartis Investigative Site, Enschede, , Netherlands

Novartis Investigative Site, Nijmegen, , Netherlands

Novartis Investigative Site, Rotterdam, , Netherlands

Novartis Investigative Site, Veldhoven, , Netherlands

Novartis Investigative Site, Skien, , Norway

Novartis Investigative Site, Malaga, Andalucia, Spain

Novartis Investigative Site, Sevilla, Andalucia, Spain

Novartis Investigative Site, Sabadell, Barcelona, Spain

Novartis Investigative Site, Santander, Cantabria, Spain

Novartis Investigative Site, Valencia, Comunidad Valenciana, Spain

Novartis Investigative Site, A Coruna, Galicia, Spain

Novartis Investigative Site, La Coruna, Galicia, Spain

Novartis Investigative Site, Alicante, , Spain

Novartis Investigative Site, Madrid, , Spain

Novartis Investigative Site, Zaragoza, , Spain

Novartis Investigative Site, Lund, , Sweden

Novartis Investigative Site, Stockholm, , Sweden

Novartis Investigative Site, Uppsala, , Sweden

Novartis Investigative Site, Chur, , Switzerland

Novartis Investigative Site, Luzern, , Switzerland

Novartis Investigative Site, Schaffhausen, , Switzerland

Novartis Investigative Site, Winterthur, , Switzerland

Novartis Investigative Site, Hull, East Yorkshire, United Kingdom

Novartis Investigative Site, Northwood, Middlesex, United Kingdom

Novartis Investigative Site, Belfast, , United Kingdom

Novartis Investigative Site, Bournemouth, , United Kingdom

Novartis Investigative Site, Bristol, , United Kingdom

Novartis Investigative Site, Chelmsford, , United Kingdom

Novartis Investigative Site, Colchester, , United Kingdom

Novartis Investigative Site, Glasgow, , United Kingdom

Novartis Investigative Site, Liverpool, , United Kingdom

Novartis Investigative Site, London, , United Kingdom

Novartis Investigative Site, London, , United Kingdom

Novartis Investigative Site, Manchester, , United Kingdom

Novartis Investigative Site, Merseyside, , United Kingdom

Novartis Investigative Site, Plymouth, , United Kingdom

Novartis Investigative Site, Rhyl, , United Kingdom

Novartis Investigative Site, Sheffiled, , United Kingdom

Novartis Investigative Site, Shrewsbury, , United Kingdom

Novartis Investigative Site, Surrey, , United Kingdom

Contact Details

Name: Novartis Pharmaceuticals

Affiliation: Novartis Pharmaceuticals

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

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