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Brief Title: Carboplatin in EARLY Triple Negative Breast Cancer Trial (PEARLY Trial)
Official Title: A Randomized, Multicenter, Open-label, Phase III Trial Comparing Anthracyclines Followed by Taxane Versus Anthracyclines Followed by Taxane Plus Carboplatin as (Neo) Adjuvant Therapy in Patients With Triple-negative Breast Cancer
Study ID: NCT02441933
Brief Summary: This is a randomized, open-label, multicenter, phase III study comparing anthracyclines followed by taxane to anthracyclines followed by taxane plus carboplatin as (neo)adjuvant therapy in patients with triple-negative breast cancer. Patients with stage II/III operable triple-negative breast cancer are eligible. Patients who need adjuvant chemotherapy after breast surgery as well as patients who need neoadjuvant chemotherapy for TNBC are eligible.
Detailed Description:
Minimum Age: 19 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Chungbuk university hospital, Cheonju, Chungchung Do, Korea, Republic of
National Cancer Center, Goyang, Gyeonggido, Korea, Republic of
National Health Insurance Service Ilsan Hospital, Ilsan, Gyeonggido, Korea, Republic of
Bundang Cha Hospital, Seongnam, Gyeonggido, Korea, Republic of
Ajou universwity Medical Center, Suwon, Gyeonggido, Korea, Republic of
Soonchunhyang university Cheonan hospital, Cheonan, Gyungkido, Korea, Republic of
Inje University Haeundae Paik Hospital, Busan, , Korea, Republic of
Keimyung University Dongsan Medical Center, Daegu, , Korea, Republic of
Gachon University Gil Medical Center, Incheon, , Korea, Republic of
Seoul national university Bundang Hospital, Seongnam, , Korea, Republic of
Asan Medical Center, Seoul, , Korea, Republic of
Boramae Medical Center, Seoul, , Korea, Republic of
Catholic university of Korea, Seoul St. Mary's Hospital, Seoul, , Korea, Republic of
Chung Ang University Heaelthcare System, Seoul, , Korea, Republic of
Gangnam Severance hospital, Seoul, , Korea, Republic of
Korea University Anam hospital, Seoul, , Korea, Republic of
Kyunghee University Healthcare System, Seoul, , Korea, Republic of
Samsung Medical Center, Seoul, , Korea, Republic of
Yonsei Cancer Center at Yonsei University Medical Center, Seoul, , Korea, Republic of
Ulsan University Hospital, Ulsan, , Korea, Republic of
Wonju Severance Christian Hospital, Wonju, , Korea, Republic of