Spots Global Cancer Trial Database for Assessment of the Anesthetic Effect on the Activity of Immune Cell in Patient With Breast Cancer
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Trial Identification
Brief Title: Assessment of the Anesthetic Effect on the Activity of Immune Cell in Patient With Breast Cancer
Official Title: Assessment of the Anesthetic Effect on the Activity of Immune Cell in Patient With Breast Cancer
Study ID: NCT02567929
Conditions
Study Description
Brief Summary: Anesthetics agents has variety inflammation during the cancer surgery. This perioperative inflammation can influence to cancer metastasis or recurrence. The purpose of this study is to prove the variation of immune cell activity between preoperative and postoperative period.
Detailed Description: The patients were allocated randomly to receive propofol or sevoflurane. Also, a total of 18ml of blood sample was obtained for total 3 times in consecutive order. 1. immediate before anesthesia induction 2. postoperative 1 hours 3. postoperative 24 hours Serum in blood will be obtained and activity of helper T cell, natural killer cell and level of serum cytokine will be evaluated by flow cytometry or enzyme-linked immunosorbent assay
Keywords
Eligibility
Minimum Age: 20 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Locations
Konkuk University Medical Center, Seoul, , Korea, Republic of
Contact Details
Name: Seong-Hyop Kim, M.D,Ph.D
Affiliation: Konkuk University Medical Center
Role: PRINCIPAL_INVESTIGATOR
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