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Brief Title: Adjuvant Ovarian Suppression Plus Aromatase Inhibitor or Tamoxifen in Young Women
Official Title: Adjuvant Ovarian Suppression Plus Aromatase Inhibitor or Tamoxifen for Hormone Receptor-Positive Breast Cancer in Women Younger Than 35: A Multicenter Randomized Clinical Trial
Study ID: NCT02914158
Brief Summary: The objective of this study is to compare the curative effects in patients under the age of 35 with hormone receptor positive breast cancer and high recurrent risk factors including large tumor or metastatic lymph nodes randomized to ovarian function suppression (OFS) plus aromatase inhibitors or OFS plus tamoxifen as adjuvant endocrine therapy, and explore the differences of curative effects between different subtypes to provide direct evidence for treatments of young breast cancer patients.
Detailed Description:
Minimum Age:
Eligible Ages: CHILD, ADULT
Sex: FEMALE
Healthy Volunteers: No
Cancer Hospital Chinese Academy of Medical Sciences, Beijing, , China
Peking University First Hospital, Beijing, , China
Dongguan People's Hospital, Dongguan, , China
GuangDong Hospital Of Traditional Chinese Medicine, Guangzhou, , China
Guangdong People's Hospital, Guangzhou, , China
Guangdong Provincial Women and Children's Hospital, Guangzhou, , China
Guangzhou First Municipal People's Hospital, Guangzhou, , China
Guangzhou Women and Childrens Medical Center, Guangzhou, , China
Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, , China
Sun Yat-sen University Cancer Center, Guangzhou, , China
The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, , China
Guilin TCMhospital of China, Guilin, , China
Zhejiang Provincial People's Hospital, Hangzhou, , China
Harbin Medical University Cancer Hospital, Harbin, , China
Yunnan Cancer Hospital, Kunming, , China
Maoming People's Hospital, Maoming, , China
The first Affiliated Hospital of Guangxi Medical University, Nanning, , China
The Affiliated Hospital of Qingdao University, Qingdao, , China
The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, , China
Affiliated hospital of Guangdong Medicine College, Zhanjiang, , China
Affiliated hospital of Guangdong Medicine College, Zhanjiang, , China
Lian Jiang People' s Hospital, Zhanjiang, , China
Henan Cancer Hospital, Zhengzhou, , China
Zhongshan People's Hospital, Zhongshan, , China
The Fifth Affiliated Hospital Sun Yat-Sen University, Zhuhai, , China