Spots Global Cancer Trial Database for Nutrition-Related Biomarkers in Predicting Breast Cancer Risk in Women
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Trial Identification
Brief Title: Nutrition-Related Biomarkers in Predicting Breast Cancer Risk in Women
Official Title: Nutrition Modulated Metabolism as a Disease Risk Factor
Study ID: NCT00900367
Conditions
Study Description
Brief Summary: RATIONALE: Studying samples of blood from patients with cancer in the laboratory may help doctors learn more about nutrition-related changes that identify biomarkers related to cancer. It may also help doctors predict a woman's risk of developing breast cancer. PURPOSE: This laboratory study is looking at nutrition-related biomarkers in predicting breast cancer risk in women.
Detailed Description: OBJECTIVES: * To complete characterization of metabolic serotypes based on the metabolome, and to adapt these profiles for human epidemiological studies. * To determine the extent to which metabolic profiles that are reflective of or independent of long-term caloric intake predict breast cancer risk in nested case-control studies. * To identify critical serum metabolites. OUTLINE: Laboratory studies, including metabolome profiling by high performance liquid chromatography; and small molecule identification by mass spectroscopy, are performed on previously collected blood samples.
Keywords
Eligibility
Minimum Age:
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: Yes
Locations
Dana-Farber/Brigham and Women's Cancer Center, Boston, Massachusetts, United States
Contact Details
Name: Bruce S. Kristal, PhD
Affiliation: Brigham and Women's Hospital
Role: STUDY_CHAIR
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