Spots Global Cancer Trial Database for APBI Versus EBRT Therapy After Breast Conserving Surgery for Low-risk Breast Cancer
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Trial Identification
Brief Title: APBI Versus EBRT Therapy After Breast Conserving Surgery for Low-risk Breast Cancer
Official Title: Interstitial Brachytherapy Alone Versus External Beam Radiation Therapy After Breast Conserving Surgery for Low-risk Invasive Carcinoma and Low-risk Ductal Carcinoma in Situ (DCIS) of the Female Breast
Study ID: NCT00402519
Conditions
Study Description
Brief Summary: To assess the role of interstitial brachytherapy alone compared to whole breast irradiation in a defined low-risk group of invasive breast cancer or ductal carcinoma in situ concerning local failure (all ipsilateral local recurrences) to affirm the hypothesis that local control rates in each arm are equivalent.
Detailed Description: To assess the role of interstitial brachytherapy alone compared to whole breast irradiation in a defined low-risk group of invasive breast cancer or ductal carcinoma in situ concerning local failure (all ipsilateral local recurrences) to affirm the hypothesis that local control rates in each arm are equivalent.
Eligibility
Minimum Age: 40 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Locations
University Hospital AKH Wien, Department of Radiotherapy and Radiobiology, Vienna, , Austria
University Hospital Erlangen, Department of Radiation Oncology, Erlangen, , Germany
University Hospital Kiel, Department of Radiation Oncology, Kiel, , Germany
University Hospital Leipzig, Department of Radiation Oncology, Leipzig, , Germany
University Hospital Lübeck, Department of Radiation Oncology, Lübeck, , Germany
Hospital Barmherzige Brüder, Department of Radiation Oncology, Regensburg, , Germany
University Hospital Rostock, Department of Radiation Oncology, Rostock, , Germany
National Institute of Oncology, Department of Radiation Oncology, Budapest, , Hungary
Kierownik Zakladu Brachyterapii, Cetrum Onkologii, Warszawa, , Poland
Catalan Institut of Oncology, Department of Radiation Oncology, Barcelona, , Spain
Valencian Institut of Oncology, Department of Radiation Oncology, Valencia, , Spain
Contact Details
Name: Vratislav Strnad, MD
Affiliation: University Hospital Erlangen, Germany
Role: STUDY_CHAIR
Name: Csaba Polgár, MD
Affiliation: National Institute of Oncology Budapest, Hungary
Role: STUDY_CHAIR
Name: Oliver J Ott, MD
Affiliation: University Hospital Erlangen, Germany
Role: STUDY_DIRECTOR
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