Spots Global Cancer Trial Database for Radiation Therapy With or Without Optional Tamoxifen in Treating Women With Ductal Carcinoma in Situ
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Trial Identification
Brief Title: Radiation Therapy With or Without Optional Tamoxifen in Treating Women With Ductal Carcinoma in Situ
Official Title: Phase III Trial of Tamoxifen Alone vs. Tamoxifen Plus Radiation Therapy for Good Risk Duct Carcinoma In-Situ (DCIS) of the Female Breast
Study ID: NCT00003857
Conditions
Study Description
Brief Summary: RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Estrogen can stimulate the growth of breast cancer cells. Hormone therapy using tamoxifen may fight breast cancer by blocking the uptake of estrogen by the tumor cells. It is not yet known if radiation therapy is more effective than observation, with or without tamoxifen, in treating ductal carcinoma in situ. PURPOSE: Randomized phase III trial to compare the effectiveness of radiation therapy with that of observation, with or without tamoxifen, in treating women who have ductal carcinoma in situ.
Detailed Description: OBJECTIVES: * Compare the efficacy of whole breast radiotherapy vs observation with or without optional tamoxifen in decreasing or delaying the appearance of local failure (both invasive and in situ) and preventing the need for mastectomy in women with good-risk ductal carcinoma in situ (DCIS) of the breast. * Compare distant disease-free survival of patients treated with these regimens. OUTLINE: This is a randomized, multicenter study. Patients are stratified according to age (under 50 vs 50 and over), final path margins (negative vs 3-9 mm vs at least 10 mm), mammographic size of primary (no greater than 1 cm vs greater than 1 cm to 2.5 cm), nuclei grade (low vs intermediate), and tamoxifen use (yes vs no). Patients are randomized to 1 of 2 treatment arms. * Arm I: Patients undergo observation and may receive optional oral tamoxifen once daily (at the discretion of the physician) for 5 years. * Arm II: Beginning within 12 weeks after final surgery, patients receive radiotherapy to the whole breast once daily, 5 days a week, for 3.5-5.5 weeks. Patients may receive optional tamoxifen as in arm I. Patients are followed every 3 months for 1 year, every 6 months for 2 years, and then annually thereafter. PROJECTED ACCRUAL: A total of 1,790 patients will be accrued for this study within 6 years.
Eligibility
Minimum Age: 26 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Locations
Mobile Infirmary Medical Center, Mobile, Alabama, United States
Fairbanks Cancer Treatment Center at Fairbanks Memorial Hospital, Fairbanks, Alaska, United States
Arizona Oncology Services Foundation, Phoenix, Arizona, United States
Saint Joseph's Mercy Cancer Center, Hot Springs, Arkansas, United States
Providence Saint Joseph Medical Center - Burbank, Burbank, California, United States
Enloe Cancer Center at Enloe Medical Center, Chico, California, United States
Mount Diablo Regional Cancer Center, Concord, California, United States
North Bay Cancer Center, Fairfield, California, United States
Washington Township Hospital, Fremont, California, United States
Saint Agnes Medical Center, Fresno, California, United States
Cancer Care Consultants Medical Associates at Daniel Freeman Memorial Hospital, Inglewood, California, United States
USC/Norris Comprehensive Cancer Center and Hospital, Los Angeles, California, United States
Providence Holy Cross Cancer Center, Mission Hills, California, United States
Memorial Medical Center Cancer Services, Modesto, California, United States
CCOP - Bay Area Tumor Institute, Oakland, California, United States
Robert and Beverly Lewis Family Cancer Care Center at Pomona Valley Hospital Medical Center, Pomona, California, United States
Radiological Associates of Sacramento Medical Group, Incorporated, Sacramento, California, United States
University of California Davis Cancer Center, Sacramento, California, United States
CCOP - Santa Rosa Memorial Hospital, Santa Rosa, California, United States
Torrance Memorial Medical Center, Torrance, California, United States
John Muir/Mt. Diablo Comprehensive Cancer Center, Walnut Creek, California, United States
Ruby L. Golleher Cancer Program at Presbyterian Intercommunity Hospital, Whittier, California, United States
St. Vincent's Medical Center, Bridgeport, Connecticut, United States
Hospital of Saint Raphael, New Haven, Connecticut, United States
Eastern Connecticut Hematology and Oncology Associates, Norwich, Connecticut, United States
CCOP - Christiana Care Health Services, Newark, Delaware, United States
Lombardi Comprehensive Cancer Center at Georgetown University Medical Center, Washington, District of Columbia, United States
University of Florida Shands Cancer Center, Gainesville, Florida, United States
Mayo Clinic - Jacksonville, Jacksonville, Florida, United States
Lakeland Regional Cancer Center at Lakeland Regional Medical Center, Lakeland, Florida, United States
University of Miami Sylvester Comprehensive Cancer Center, Miami, Florida, United States
Baptist-South Miami Regional Cancer Program, Miami, Florida, United States
Northeast Georgia Medical Center, Gainesville, Georgia, United States
Nancy N. and J. C. Lewis Cancer and Research Pavilion at St. Joseph's/Candler, Savannah, Georgia, United States
Leeward Radiation Oncology Center, 'Ewa Beach, Hawaii, United States
Cancer Research Center of Hawaii, Honolulu, Hawaii, United States
Queen's Cancer Institute at Queen's Medical Center, Honolulu, Hawaii, United States
St. Francis Medical Center, Honolulu, Hawaii, United States
Tripler Army Medical Center, Honolulu, Hawaii, United States
St. Luke's Mountain States Tumor Institute - Boise, Boise, Idaho, United States
Hematology Oncology Associates of Eastern Idaho, Idaho Falls, Idaho, United States
Northwest Community Hospital, Arlington Heights, Illinois, United States
Rush-Copley Cancer Care Center, Aurora, Illinois, United States
Good Shepherd Hospital, Barrington, Illinois, United States
St. Joseph Medical Center, Bloomington, Illinois, United States
Robert H. Lurie Comprehensive Cancer Center at Northwestern University, Chicago, Illinois, United States
John H. Stroger, Jr. Hospital of Cook County, Chicago, Illinois, United States
Creticos Cancer Center at Advocate Illinois Masonic Medical Center, Chicago, Illinois, United States
Advocate Good Samaritan Hospital, Downers Grove, Illinois, United States
InterCommunity Cancer Center of Western Illinois, Galesburg, Illinois, United States
Joliet Oncology-Hematology Associates, Limited - West, Joliet, Illinois, United States
Cardinal Bernardin Cancer Center at Loyola University Medical Center, Maywood, Illinois, United States
BroMenn Regional Medical Center, Normal, Illinois, United States
Community Cancer Center, Normal, Illinois, United States
Lutheran General Cancer Care Center, Park Ridge, Illinois, United States
Cancer Treatment Center at Pekin Hospital, Pekin, Illinois, United States
CCOP - Illinois Oncology Research Association, Peoria, Illinois, United States
Oncology Hematology Associates of Central Illinois, PC - Peoria, Peoria, Illinois, United States
Methodist Medical Center of Illinois, Peoria, Illinois, United States
OSF St. Francis Medical Center, Peoria, Illinois, United States
Valley Cancer Center, Spring Valley, Illinois, United States
Carle Cancer Center at Carle Foundation Hospital, Urbana, Illinois, United States
CCOP - Carle Cancer Center, Urbana, Illinois, United States
St. John's Cancer Center at St. John's Medical Center, Anderson, Indiana, United States
Regional Cancer Institute at Bloomington Hospital, Bloomington, Indiana, United States
Elkhart General Hospital, Elkhart, Indiana, United States
Parkview Regional Cancer Center at Parkview Health, Fort Wayne, Indiana, United States
Indiana University Cancer Center, Indianapolis, Indiana, United States
Howard Community Hospital at Howard Regional Health System, Kokomo, Indiana, United States
Center for Cancer Therapy at LaPorte Hospital and Health Services, La Porte, Indiana, United States
Saint Anthony Memorial Health Centers, Michigan City, Indiana, United States
CCOP - Northern Indiana CR Consortium, South Bend, Indiana, United States
Memorial Hospital of South Bend, South Bend, Indiana, United States
St. Luke's Hospital, Cedar Rapids, Iowa, United States
Cedar Rapids Oncology Associates, Cedar Rapids, Iowa, United States
Mercy Regional Cancer Center at Mercy Medical Center, Cedar Rapids, Iowa, United States
Stormont-Vail Cancer Center, Topeka, Kansas, United States
St. Francis Comprehensive Cancer Center, Topeka, Kansas, United States
Cancer Treatment Center for Southern Kentucky, Bowling Green, Kentucky, United States
Central Baptist Hospital, Lexington, Kentucky, United States
Merle M. Mahr Cancer Center at Regional Medical Center of Hopkins County, Madisonville, Kentucky, United States
Central Maine Medical Center, Lewiston, Maine, United States
Maine Medical Center - Bramhall Campus, Portland, Maine, United States
DeCesaris Cancer Institute at Anne Arundel Medical Center, Annapolis, Maryland, United States
Greater Baltimore Medical Center, Baltimore, Maryland, United States
Suburban Hospital, Bethesda, Maryland, United States
Peninsula Regional Medical Center, Salisbury, Maryland, United States
Massachusetts General Hospital Cancer Center, Boston, Massachusetts, United States
Brigham and Women's Hospital, Boston, Massachusetts, United States
Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute, Boston, Massachusetts, United States
Cancer Research Center at Boston Medical Center, Boston, Massachusetts, United States
Lahey Clinic Medical Center - Burlington, Burlington, Massachusetts, United States
Bethke Cancer Center at Emerson Hospital, Concord, Massachusetts, United States
Hudner Oncology Center at Saint Anne's Hospital, Fall River, Massachusetts, United States
MetroWest Medical Center - Framingham Union Hospital, Framingham, Massachusetts, United States
Cape Cod Hospital, Hyannis, Massachusetts, United States
Lowell General Hospital, Lowell, Massachusetts, United States
Community Cancer Care at Milford Regional Medical Center, Milford, Massachusetts, United States
Caritas Norwood Hospital, Norwood, Massachusetts, United States
Baystate Regional Cancer Program at D'Amour Center for Cancer Care, Springfield, Massachusetts, United States
Hickman Cancer Center at Bixby Medical Center, Adrian, Michigan, United States
St. Joseph Mercy Cancer Center at St. Joseph Mercy Hospital, Ann Arbor, Michigan, United States
CCOP - Michigan Cancer Research Consortium, Ann Arbor, Michigan, United States
University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, United States
Barbara Ann Karmanos Cancer Institute, Detroit, Michigan, United States
Josephine Ford Cancer Center at Henry Ford Hospital, Detroit, Michigan, United States
Green Bay Oncology, Limited - Escanaba, Escanaba, Michigan, United States
Genesys Hurley Cancer Institute, Flint, Michigan, United States
Great Lakes Cancer Institute at McLaren Regional Medical Center, Flint, Michigan, United States
CCOP - Grand Rapids, Grand Rapids, Michigan, United States
Lacks Cancer Center at Saint Mary's Mercy Medical Center, Grand Rapids, Michigan, United States
Spectrum Health Cancer Care - Butterworth Campus, Grand Rapids, Michigan, United States
Van Elslander Cancer Center at St. John Hospital and Medical Center, Grosse Pointe Woods, Michigan, United States
Green Bay Oncology, Limited - Iron Mountain, Iron Mountain, Michigan, United States
Foote Hospital, Jackson, Michigan, United States
Borgess Medical Center, Kalamazoo, Michigan, United States
West Michigan Cancer Center, Kalamazoo, Michigan, United States
Bronson Methodist Hospital, Kalamazoo, Michigan, United States
Breslin Cancer Center at Ingham Regional Medical Center, Lansing, Michigan, United States
Upper Michigan Cancer Center at Marquette General Hospital, Marquette, Michigan, United States
MidMichigan Medical Center - Midland, Midland, Michigan, United States
Northern Michigan Hospital, Petoskey, Michigan, United States
William Beaumont Hospital - Royal Oak Campus, Royal Oak, Michigan, United States
Seton Cancer Institute - Saginaw, Saginaw, Michigan, United States
Lakeland Cancer Care Center at Lakeland Hospital - St. Joseph, Saint Joseph, Michigan, United States
Munson Medical Center, Traverse City, Michigan, United States
St. John Macomb Hospital, Warren, Michigan, United States
Fairview Ridges Hospital, Burnsville, Minnesota, United States
Mercy and Unity Cancer Center at Mercy Hospital, Coon Rapids, Minnesota, United States
St. Mary's - Duluth Clinic Cancer Center, Duluth, Minnesota, United States
Fairview Southdale Hospital, Edina, Minnesota, United States
Mercy and Unity Cancer Center at Unity Hospital, Fridley, Minnesota, United States
Immanuel St. Joseph's Clinic, Mankato, Minnesota, United States
Virginia Piper Cancer Institute at Abbott-Northwestern Hospital, Minneapolis, Minnesota, United States
Hubert H. Humphrey Cancer Center at North Memorial Medical Center, Robbinsdale, Minnesota, United States
Mayo Clinic Cancer Center, Rochester, Minnesota, United States
CentraCare Clinic - River Campus, Saint Cloud, Minnesota, United States
Coborn Cancer Center, Saint Cloud, Minnesota, United States
CCOP - Metro-Minnesota, Saint Louis Park, Minnesota, United States
Park Nicollet Health Services, Saint Louis Park, Minnesota, United States
Regions Hospital Cancer Care Center, Saint Paul, Minnesota, United States
United Hospital, Saint Paul, Minnesota, United States
Ridgeview Medical Center, Waconia, Minnesota, United States
University of Mississippi Medical Center, Jackson, Mississippi, United States
Ellis Fischel Cancer Center at University of Missouri - Columbia, Columbia, Missouri, United States
CCOP - Kansas City, Kansas City, Missouri, United States
CCOP - Montana Cancer Consortium, Billings, Montana, United States
Northern Rockies Radiation Oncology Center, Billings, Montana, United States
Deaconess Billings Clinic - Downtown, Billings, Montana, United States
Great Falls Clinic, Great Falls, Montana, United States
Good Samaritan Cancer Center at Good Samaritan Hospital, Kearney, Nebraska, United States
Methodist Cancer Center at Methodist Hospital - Omaha, Omaha, Nebraska, United States
CCOP - Nevada Cancer Research Foundation, Las Vegas, Nevada, United States
Dartmouth - Hitchcock Concord, Concord, New Hampshire, United States
Seacoast Cancer Center at Wentworth-Douglass Hospital, Dover, New Hampshire, United States
Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, United States
Elliot Regional Cancer Center at Elliot Hospital, Manchester, New Hampshire, United States
Veterans Affairs Medical Center - East Orange, East Orange, New Jersey, United States
John F. Kennedy Medical Center, Edison, New Jersey, United States
Dizzy Gillespie Cancer Institute at Englewood Hospital and Medical Center, Englewood, New Jersey, United States
Monmouth Medical Center, Long Branch, New Jersey, United States
Fox Chase Virtua Health Cancer Program - Marlton, Marlton, New Jersey, United States
Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School, New Brunswick, New Jersey, United States
Saint Peter's University Hospital, New Brunswick, New Jersey, United States
Newark Beth Israel Medical Center, Newark, New Jersey, United States
AtlantiCare Regional Medical Center, Pomona, New Jersey, United States
Booker Cancer Center at Riverview Medical Center, Red Bank, New Jersey, United States
Fox Chase Cancer Center at St. Francis Medical Center, Trenton, New Jersey, United States
Cancer Institute of New Jersey at Cooper - Voorhees, Voorhees, New Jersey, United States
Albuquerque Regional Medical Center at Lovelace Sandia Health System, Albuquerque, New Mexico, United States
University of New Mexico Cancer Research and Treatment Center, Albuquerque, New Mexico, United States
Long Island College Hospital, Brooklyn, New York, United States
Roswell Park Cancer Institute, Buffalo, New York, United States
CCOP - North Shore University Hospital, Manhasset, New York, United States
North Shore University Hospital, Manhasset, New York, United States
Tucker Center for Cancer Care at Orange Regional Medical Center, Middletown, New York, United States
Long Island Jewish Medical Center, New Hyde Park, New York, United States
Memorial Sloan-Kettering Cancer Center, New York, New York, United States
CCOP - Hematology-Oncology Associates of Central New York, Syracuse, New York, United States
Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill, Chapel Hill, North Carolina, United States
Blumenthal Cancer Center at Carolinas Medical Center, Charlotte, North Carolina, United States
Batte Cancer Center at Northeast Medical Center, Concord, North Carolina, United States
Duke Comprehensive Cancer Center, Durham, North Carolina, United States
Wayne Memorial Hospital, Incorporated, Goldsboro, North Carolina, United States
Wayne Radiation Oncology, Goldsboro, North Carolina, United States
Leo W. Jenkins Cancer Center at Pitt County Memorial Hospital, Greenville, North Carolina, United States
Pardee Memorial Hospital, Hendersonville, North Carolina, United States
Lenoir Memorial Cancer Center, Kinston, North Carolina, United States
Moore Regional Community Hospital Comprehensive Cancer Center, Pinehurst, North Carolina, United States
Rex Cancer Center at Rex Hospital, Raleigh, North Carolina, United States
Rutherford Hospital, Rutherfordton, North Carolina, United States
Zimmer Cancer Center at New Hanover Regional Medical Center, Wilmington, North Carolina, United States
Wilmed Radiation Oncology Services, Wilson, North Carolina, United States
Trinity Cancer Care Center, Minot, North Dakota, United States
McDowell Cancer Center at Akron General Medical Center, Akron, Ohio, United States
Mercy Cancer Center at Mercy Medical Center, Canton, Ohio, United States
Adena Regional Medical Center, Chillicothe, Ohio, United States
Cancer Treatment Center at Good Samaritan Hospital, Cincinnati, Ohio, United States
Bethesda North Hospital, Cincinnati, Ohio, United States
Case Comprehensive Cancer Center, Cleveland, Ohio, United States
MetroHealth's Cancer Care Center at MetroHealth Medical Center, Cleveland, Ohio, United States
Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio, United States
Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University, Columbus, Ohio, United States
Riverside Methodist Hospital Cancer Care, Columbus, Ohio, United States
CCOP - Columbus, Columbus, Ohio, United States
Mount Carmel Health - West Hospital, Columbus, Ohio, United States
Grady Memorial Hospital, Delaware, Ohio, United States
Blanchard Valley Medical Associates, Findlay, Ohio, United States
St. Rita's Medical Center, Lima, Ohio, United States
Lima Memorial Hospital, Lima, Ohio, United States
Strecker Cancer Center at Marietta Memorial Hospital, Marietta, Ohio, United States
Northwest Ohio Oncology Center, Maumee, Ohio, United States
Hillcrest Cancer Center at Hillcrest Hospital, Mayfield Heights, Ohio, United States
Licking Memorial Cancer Care Program at Licking Memorial Hospital, Newark, Ohio, United States
St. Charles Mercy Hospital, Oregon, Ohio, United States
Firelands Regional Medical Center, Sandusky, Ohio, United States
Mercy Medical Center, Springfield, Ohio, United States
Promedica Cancer Center at Flower Hospital, Sylvania, Ohio, United States
St. Vincent Mercy Medical Center, Toledo, Ohio, United States
Medical University of Ohio Cancer Center, Toledo, Ohio, United States
CCOP - Toledo Community Hospital, Toledo, Ohio, United States
Toledo Clinic, Incorporated - Main Clinic, Toledo, Ohio, United States
St. Joseph Cancer Center at St. Joseph Health Center, Warren, Ohio, United States
Mount Carmel Cancer Services at Mount Carmel St. Ann's Hospital, Westerville, Ohio, United States
Natalie Warren Bryant Cancer Center at St. Francis Hospital, Tulsa, Oklahoma, United States
Three Rivers Community Hospital, Grants Pass, Oregon, United States
Legacy Mount Hood Medical Center, Gresham, Oregon, United States
Dubs Cancer Center at Rogue Valley Medical Center, Medford, Oregon, United States
Providence Medford Medical Center, Medford, Oregon, United States
Providence Milwaukie Hospital, Milwaukie, Oregon, United States
Legacy Good Samaritan Hospital & Medical Center Comprehensive Cancer Center, Portland, Oregon, United States
Providence Cancer Center at Providence Portland Medical Center, Portland, Oregon, United States
CCOP - Columbia River Oncology Program, Portland, Oregon, United States
Providence St. Vincent Medical Center, Portland, Oregon, United States
Legacy Emanuel Hospital and Health Center & Children's Hospital, Portland, Oregon, United States
Cancer Institute at Oregon Health and Science University, Portland, Oregon, United States
Legacy Meridian Park Hospital, Tualatin, Oregon, United States
Rosenfeld Cancer Center at Abington Memorial Hospital, Abington, Pennsylvania, United States
St. Luke's Hospital Cancer Center, Bethlehem, Pennsylvania, United States
Bryn Mawr Hospital, Bryn Mawr, Pennsylvania, United States
Geisinger Medical Center, Danville, Pennsylvania, United States
Mercy Fitzgerald Hospital, Darby, Pennsylvania, United States
Easton Regional Cancer Center at Easton Hospital, Easton, Pennsylvania, United States
St. Mary Regional Cancer Center, Langhorne, Pennsylvania, United States
Paoli Memorial Hospital, Paoli, Pennsylvania, United States
Kimmel Cancer Center at Thomas Jefferson University - Philadelphia, Philadelphia, Pennsylvania, United States
Fox Chase-Temple Cancer Center CCOP Research Base, Philadelphia, Pennsylvania, United States
Mercy Cancer Institute at Mercy Hospital, Pittsburgh, Pennsylvania, United States
Hillman Cancer Center at University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States
Reading Hospital and Medical Center, Reading, Pennsylvania, United States
Mercy Hospital Cancer Center - Scranton, Scranton, Pennsylvania, United States
Mount Nittany Medical Center, State College, Pennsylvania, United States
Frank M. and Dorothea Henry Cancer Center at Geisinger Wyoming Valley Medical Center, Wilkes-Barre, Pennsylvania, United States
CCOP - MainLine Health, Wynnewood, Pennsylvania, United States
Lankenau Cancer Center at Lankenau Hospital, Wynnewood, Pennsylvania, United States
York Cancer Center at Wellspan Health, York, Pennsylvania, United States
AnMed Health Cancer Center, Anderson, South Carolina, United States
Palmetto Health South Carolina Cancer Center, Columbia, South Carolina, United States
Bon Secours St. Francis Health System, Greenville, South Carolina, United States
CCOP - Greenville, Greenville, South Carolina, United States
CCOP - Upstate Carolina, Spartanburg, South Carolina, United States
Gibbs Regional Cancer Center at Spartanburg Regional Medical Center, Spartanburg, South Carolina, United States
Rapid City Regional Hospital, Rapid City, South Dakota, United States
Medical X-Ray Center, PC, Sioux Falls, South Dakota, United States
Sioux Valley Hospital and University of South Dakota Medical Center, Sioux Falls, South Dakota, United States
University of Texas Medical Branch, Galveston, Texas, United States
M.D. Anderson Cancer Center at University of Texas, Houston, Texas, United States
Doctor's Hospital of Laredo, Laredo, Texas, United States
Joe Arrington Cancer Research and Treatment Center, Lubbock, Texas, United States
Cottonwood Hospital Medical Center, Murray, Utah, United States
McKay-Dee Hospital Center, Ogden, Utah, United States
Utah Valley Regional Medical Center - Provo, Provo, Utah, United States
Dixie Regional Medical Center - East Campus, Saint George, Utah, United States
Utah Cancer Specialists at UCS Cancer Center, Salt Lake City, Utah, United States
LDS Hospital, Salt Lake City, Utah, United States
Fletcher Allen Health Care - University Health Center Campus, Burlington, Vermont, United States
Community Cancer Center at Rutland Regional Medical Center, Rutland, Vermont, United States
Martha Jefferson Hospital Cancer Care Center, Charlottesville, Virginia, United States
Naval Medical Center - Portsmouth, Portsmouth, Virginia, United States
St. Francis Hospital, Federal Way, Washington, United States
Cascade Cancer Center at Evergreen Hospital Medical Center, Kirkland, Washington, United States
CCOP - Virginia Mason Research Center, Seattle, Washington, United States
Group Health Central Hospital, Seattle, Washington, United States
Swedish Cancer Institute at Swedish Medical Center - First Hill Campus, Seattle, Washington, United States
University Cancer Center at University of Washington Medical Center, Seattle, Washington, United States
Cancer Care Northwest - Spokane South, Spokane, Washington, United States
Madigan Army Medical Center - Tacoma, Tacoma, Washington, United States
Southwest Washington Medical Center Cancer Center, Vancouver, Washington, United States
Theda Care Cancer Institute, Appleton, Wisconsin, United States
Green Bay Oncology, Limited at St. Vincent Hospital, Green Bay, Wisconsin, United States
Green Bay Oncology, Limited at St. Mary's Hospital, Green Bay, Wisconsin, United States
St. Mary's Hospital Medical Center - Green Bay, Green Bay, Wisconsin, United States
St. Vincent Hospital Regional Cancer Center, Green Bay, Wisconsin, United States
Vince Lombardi Cancer Clinic - Green Bay at Aurora BayCare Medical Center, Green Bay, Wisconsin, United States
Gundersen Lutheran Cancer Center at Gundersen Lutheran Medical Center, La Crosse, Wisconsin, United States
University of Wisconsin Comprehensive Cancer Center, Madison, Wisconsin, United States
Bay Area Cancer Care Center at Bay Area Medical Center, Marinette, Wisconsin, United States
Community Memorial Hospital Cancer Care Center, Menomonee Falls, Wisconsin, United States
Columbia St. Mary's Cancer Care Center, Milwaukee, Wisconsin, United States
Vince Lombardi Cancer Clinic at Aurora St. Luke's Medical Center, Milwaukee, Wisconsin, United States
Regional Cancer Center at Oconomowoc Memorial Hospital, Oconomowoc, Wisconsin, United States
Green Bay Oncology, Limited - Oconto Falls, Oconto Falls, Wisconsin, United States
Green Bay Oncology, Limited - Sturgeon Bay, Sturgeon Bay, Wisconsin, United States
Waukesha Memorial Hospital Regional Cancer Center, Waukesha, Wisconsin, United States
West Allis Memorial Hospital, West Milwaukee, Wisconsin, United States
Cross Cancer Institute at University of Alberta, Edmonton, Alberta, Canada
Lethbridge Cancer Centre, Lethbridge, Alberta, Canada
British Columbia Cancer Agency - Centre for the Southern Interior, Kelowna, British Columbia, Canada
Nanaimo Cancer Clinic at Nanaimo Regional General Hospital, Nanaimo, British Columbia, Canada
Lions Gate Hospital, North Vancouver, British Columbia, Canada
BCCA - Fraser Valley Cancer Centre, Surrey, British Columbia, Canada
Prostate Centre at Vancouver General Hospital, Vancouver, British Columbia, Canada
British Columbia Cancer Agency - Vancouver Cancer Centre, Vancouver, British Columbia, Canada
Providence Health Care - Vancouver, Vancouver, British Columbia, Canada
British Columbia Cancer Agency - Vancouver Island Cancer Centre, Victoria, British Columbia, Canada
G. Steinhoff Clinical Research, Victoria, British Columbia, Canada
CancerCare Manitoba, Winnipeg, Manitoba, Canada
Moncton Hospital, Moncton, New Brunswick, Canada
Saint John Regional Hospital, Saint John, New Brunswick, Canada
Newfoundland Cancer Treatment and Research Foundation, St. Johns, Newfoundland and Labrador, Canada
Nova Scotia Cancer Centre, Halifax, Nova Scotia, Canada
Cape Breton Cancer Centre, Sydney, Nova Scotia, Canada
Royal Victoria Hospital of Barrie, Barrie, Ontario, Canada
William Osler Health Centre, Brampton, Ontario, Canada
St. Joseph's Hospital, Hamilton, Ontario, Canada
Margaret and Charles Juravinski Cancer Centre, Hamilton, Ontario, Canada
Cancer Centre of Southeastern Ontario at Kingston General Hospital, Kingston, Ontario, Canada
Grand River Regional Cancer Centre at Grand River Hospital, Kitchner, Ontario, Canada
London Regional Cancer Program at London Health Sciences Centre, London, Ontario, Canada
Markham Stouffville Hospital, Markham, Ontario, Canada
Trillium Health Centre - Mississauga Site, Mississauga, Ontario, Canada
Southlake Regional Health Centre, Newmarket, Ontario, Canada
North York General Hospital - Ontario, North York, Ontario, Canada
Male Health Centre - Oakville, Oakville, Ontario, Canada
R. S. McLaughlin Durham Regional Cancer Centre at Lakeridge Health Oshawa, Oshawa, Ontario, Canada
Ottawa Hospital Regional Cancer Centre - General Campus, Ottawa, Ontario, Canada
Peterborough Oncology Clinic, Peterborough, Ontario, Canada
Algoma Regional Cancer Program at Sault Area Hospital, Sault Sainte Marie, Ontario, Canada
Scarborough Hospital - General Campus, Scarborough, Ontario, Canada
St. Catharines General Hospital at Niagara Health System, St. Catharines, Ontario, Canada
Northeastern Ontario Regional Cancer Centre, Sudbury, Ontario, Canada
Northwestern Ontario Regional Cancer Care at Thunder Bay Regional Health Sciences Centre, Thunder Bay, Ontario, Canada
Toronto East General Hospital, Toronto, Ontario, Canada
Toronto Sunnybrook Regional Cancer Centre at Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
St. Michael's Hospital - Toronto, Toronto, Ontario, Canada
Mount Sinai Hospital - Toronto, Toronto, Ontario, Canada
Princess Margaret Hospital, Toronto, Ontario, Canada
Male Health Centre - North York, Toronto, Ontario, Canada
St. Joseph's Health Centre - Toronto, Toronto, Ontario, Canada
Humber River Regional Hospital - Weston, Weston, Ontario, Canada
Windsor Regional Cancer Centre at Windsor Regional Hospital, Windsor, Ontario, Canada
Prince Edward Island Cancer Centre at Queen Elizabeth Hospital, Charlottetown, Prince Edward Island, Canada
Centre de Sante et de Services Sociaux de Chicoutimi, Chicoutimi, Quebec, Canada
CHUS-Hopital Fleurimont, Fleurimont, Quebec, Canada
Doctor Leon Richard Oncology Centre, Greenfield Park, Quebec, Canada
Hopital Charles Lemoyne, Greenfield Park, Quebec, Canada
Centre Hospitalier Regional de Lanaudiere, Joliette, Quebec, Canada
Hotel-Dieu de Levis, Levis, Quebec, Canada
Centre Hospitalier de l'Universite de Montreal, Montreal, Quebec, Canada
Maisonneuve-Rosemont Hospital, Montreal, Quebec, Canada
Hotel Dieu de Montreal, Montreal, Quebec, Canada
Hopital Sainte Justine, Montreal, Quebec, Canada
Hopital Du Sacre-Coeur de Montreal, Montreal, Quebec, Canada
Centre Hospitalier Universitaire de Quebec, Quebec City, Quebec, Canada
Hopital du Saint-Sacrement - Quebec, Quebec City, Quebec, Canada
L'Hopital Laval, Ste-Foy, Quebec, Canada
Allan Blair Cancer Centre at Pasqua Hospital, Regina, Saskatchewan, Canada
Saskatoon Cancer Centre at the University of Saskatchewan, Saskatoon, Saskatchewan, Canada
Centre Hospitalier Regional de Rimouski, Quebec, , Canada
Contact Details
Name: Beryl McCormick, MD
Affiliation: Memorial Sloan Kettering Cancer Center
Role: STUDY_CHAIR
Name: Clifford A. Hudis, MD
Affiliation: Memorial Sloan Kettering Cancer Center
Role:
Name: Barbara L. Smith, MD, PhD
Affiliation: Massachusetts General Hospital
Role: STUDY_CHAIR
Name: Timothy J. Whelan, MD
Affiliation: Margaret and Charles Juravinski Cancer Centre
Role: STUDY_CHAIR
Name: Eileen Rakovitch, MD
Affiliation: Toronto Sunnybrook Regional Cancer Centre
Role:
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