Spots Global Cancer Trial Database for Epidemiological Analysis of Vitamin D and Breast Cancer Risk in Saudi Arabian Women

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Trial Identification

Brief Title: Epidemiological Analysis of Vitamin D and Breast Cancer Risk in Saudi Arabian Women

Official Title: Vitamin D Status and Breast Cancer in Saudi Arabian Women: Case Control Study

Study ID: NCT01817231

Conditions

Breast Cancer

Vitamin D Deficiency

Interventions

Study Description

Brief Summary: This is an analysis of de-identified data collected from 240 Saudi Arabian women, 120 with breast cancer and 120 control women, to evalyate if vitamin D status is associated with breast cancer risk.

Detailed Description: Background: The role of vitamin D in breast cancer prevention is equivocal. Saudi Arabian women are thought to be at greater risk for vitamin D deficiency due to darker skin type and greater likelihood for reduced UVB radiation exposure. However, there is a lack of data regarding the vitamin D status of Saudi Arabian women and how this may relate to breast cancer risk. Objective: The purpose of this research was to evaluate the association between circulating concentrations of 25(OH)D and breast cancer risk in Saudi Arabian women. Design: A case-control study was conducted among 120 breast cancer cases and 120 controls. The study population was drawn from patients admitted to King Fahd Hospital in Jeddah, Saudi Arabia from June to August 2009. Participants completed questionnaires on diet and medical history and serum samples were collected from all women to measure circulating 25(OH)D concentrations.