Spots Global Cancer Trial Database for A Study of LY3484356 in Women With Breast Cancer Before Having Surgery
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Trial Identification
Brief Title: A Study of LY3484356 in Women With Breast Cancer Before Having Surgery
Official Title: EMBER-2: A Phase 1, Open-Label, Preoperative Window Study Evaluating the Biological Effects of LY3484356 in Post-menopausal Women With Stage I-III Estrogen Receptor-Positive, HER2-Negative Breast Cancer
Study ID: NCT04647487
Conditions
Interventions
Study Description
Brief Summary: The purpose for this study is to see if the study drug, LY3484356, is safe and to determine what effects it has on breast cancer in participants with Estrogen Receptor Positive (ER+), HER2 Negative (HER2-) early stage (stage I-III) breast cancer, when given prior to surgery. Participation in this study could last up to 2.5 months.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Locations
Winship Cancer Center Emory University, Atlanta, Georgia, United States
Northwestern Memorial Hosptial, Chicago, Illinois, United States
Massachusetts General Hospital, Boston, Massachusetts, United States
Washington University School of Medicine, Saint Louis, Missouri, United States
Sarah Cannon Research Institute SCRI, Nashville, Tennessee, United States
Baylor College of Medicine, Houston, Texas, United States
University of Texas MD Anderson Cancer Center, Houston, Texas, United States
University of Vermont Medical Center, Burlington, Vermont, United States
Institut Jules Bordet, Brussel - Capital, , Belgium
Universitaire Ziekenhuizen Leuven - Campus Gasthuisberg, Leuven, , Belgium
Hôpital René Huguenin, Saint-Cloud, Hauts-de-Seine, France
Universitätsklinikum Erlangen, Erlangen, Bayern, Germany
Helios Kliniken Schwerin, Schwerin, Mecklenburg-Vorpommern, Germany
Klinikum der Universitaet Muenchen, Muenchen, , Germany
Hospital Clinic I Provincial, Barcelona, , Spain
Hospital General Universitario Gregorio Marañon, Madrid, , Spain
Hospital Madrid Norte Sanchinarro, Madrid, , Spain
The Royal Cornwall Hospital, Truro, Cornwall, United Kingdom
Barts Cancer Institute, London, London City, United Kingdom
Contact Details
Name: Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST)
Affiliation: Eli Lilly and Company
Role: STUDY_DIRECTOR
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