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Brief Title: An Examination of Predictors of Indicators of Response to Letrozole 2.5 mg
Official Title: Quantitative Real Time PCR in Cytolytic Formalin Fixed Breast Cells Obtained by Periareolar Fine Needle Aspiration. An Ancillary Protocol to a Chemoprevention Trial of Letrozole
Study ID: NCT00291109
Brief Summary: To assess the quantitative real time PCR results of oligonucleotide probes for a number of gene transcription products that may be useful as predictors or indicators of response to letrozole
Detailed Description: To assess the quantitative real time PCR results of oligonucleotide probes for a number of gene transcription products (PCNA, cyclin-D1, ER alpha, PR, pS2, 450 aromatase, bcl-2, bax, caspase-3, and VEGFR) that may be useful as predictors or indicators of response to letrozole
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
University of Kansas Medical Center, Kansas City, Kansas, United States
Name: Carol J Fabian, MD
Affiliation: University of Kansas Medical Center
Role: PRINCIPAL_INVESTIGATOR