Spots Global Cancer Trial Database for Partial Breast Radiation Therapy in Treating Women Undergoing Breast-Conserving Therapy for Early Stage Breast Cancer

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Trial Identification

Brief Title: Partial Breast Radiation Therapy in Treating Women Undergoing Breast-Conserving Therapy for Early Stage Breast Cancer

Official Title: Partial Breast Irradiation for Patients Undergoing Breast Conservation Therapy for Early Stage Breast Cancer: A Pilot Study

Study ID: NCT00527293

Conditions

Breast Cancer

Interventions

adjuvant therapy

3-dimensional conformal radiation therapy

brachytherapy

Study Description

Brief Summary: RATIONALE: Radiation therapy uses high-energy x-rays and other types of radiation to kill tumor cells. Giving radiation therapy in different ways may kill more tumor cells. PURPOSE: This clinical trial is studying how well partial breast radiation therapy works in treating women undergoing breast-conserving therapy for early stage breast cancer.

Detailed Description: OBJECTIVES: * To determine the cosmetic outcome resulting from partial breast irradiation using two different techniques. * To determine patient satisfaction with partial breast irradiation as it pertains to their overall treatment experience as measured by a questionnaire. * To determine if there are patient factors that limit a patient's suitability to receive partial breast irradiation delivered by a particular technique. * To evaluate wound healing and overall complication rate after partial breast irradiation. * To determine ipsilateral breast tumor recurrence rates and tumor bed recurrence rates. OUTLINE: Patients undergo partial breast irradiation comprising either MammoSite® brachytherapy twice daily for 5-10 days OR 3-dimensional conformal radiotherapy twice daily for 5-10 days. After completion of study therapy, patients are followed periodically for up to 5 years.