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Spots Global Cancer Trial Database for Study of Tamoxifen and Raloxifene (STAR) for the Prevention of Breast Cancer in Postmenopausal Women

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Study of Tamoxifen and Raloxifene (STAR) for the Prevention of Breast Cancer in Postmenopausal Women

Official Title: Study of Tamoxifen and Raloxifene (STAR) for the Prevention of Breast Cancer

Study ID: NCT00003906

Conditions

Breast Cancer

Interventions

Raloxifene
Tamoxifen

Study Description

Brief Summary: RATIONALE: Estrogen can stimulate the growth of breast cancer cells. Hormone therapy using raloxifene and tamoxifen may fight breast cancer by blocking the uptake of estrogen by the tumor cells. PURPOSE: Randomized double-blinded clinical trial to compare the effectiveness of raloxifene with that of tamoxifen in preventing breast cancer in postmenopausal women.

Detailed Description: OBJECTIVES: * Determine whether raloxifene is more or less effective than tamoxifen in significantly reducing the incidence rate of invasive breast cancer in postmenopausal women. * Evaluate the effects of tamoxifen and raloxifene on the incidence of intraductal carcinoma in situ, lobular carcinoma in situ, endometrial cancer, ischemic heart disease, fractures of the hip and spine, or Colles' fractures of the wrist in these participants. * Evaluate the toxic effects of these regimens in these participants. * Determine the effect of these regimens on the quality of life of these participants (at selected centers). (Quality of life evaluation closed to accrual effective 5/31/01.) OUTLINE: This is a randomized, double-blind study. Participants are stratified by age (35 to 49 vs 50 to 59 vs over 59), race (black vs white vs other), history of lobular carcinoma in situ (yes vs no), prior hysterectomy (yes vs no), and estimated absolute risk of invasive breast cancer within 5 years (using the Gail model)(less than 2.0 vs 2.0-2.9 vs 3.0-4.9 vs 5.0 or greater). Participants are randomized to 1 of 2 arms. * Arm I: Participants receive oral tamoxifen plus placebo daily for 5 years. * Arm II: Participants receive oral raloxifene plus placebo daily for 5 years. Quality of life is assessed (at selected centers) at baseline and at 6, 12, 18, 24, 30, 36, 42, 48, 54, 60, and 72 months. (Quality of life evaluation closed to accrual effective 5/31/01.) Participants are followed annually after 5 years. PROJECTED ACCRUAL: Approximately 19,000 participants will be accrued for this study within 5 years.

Eligibility

Minimum Age: 35 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: FEMALE

Healthy Volunteers: No

Locations

Comprehensive Cancer Institute, Huntsville, Alabama, United States

MBCCOP - Gulf Coast, Mobile, Alabama, United States

Providence Alaska Medical Center, Anchorage, Alaska, United States

CCOP - Western Regional, Arizona, Phoenix, Arizona, United States

CCOP - Mayo Clinic Scottsdale Oncology Program, Scottsdale, Arizona, United States

Arizona Cancer Center at University of Arizona Health Sciences Center, Tucson, Arizona, United States

Breast Associates, Fayetteville, Arkansas, United States

Surgical Associates, Fort Smith, Arkansas, United States

Northeast Arkansas Clinic, Jonesboro, Arkansas, United States

Arkansas Cancer Research Center at University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

Kaiser Permanente Medical Center - Anaheim/Orange County, Anaheim, California, United States

Kaiser Permanente Medical Center - Baldwin Park, Baldwin Park, California, United States

Kaiser Permanente Medical Center - Bellflower, Bellflower, California, United States

Alta Bates Comprehensive Cancer Center, Berkeley, California, United States

Providence Saint Joseph Medical Center - Burbank, Burbank, California, United States

Mills-Peninsula Health Services, Burlingame, California, United States

Enloe Cancer Center at Enloe Medical Center, Chico, California, United States

Mount Diablo Medical Center, Concord, California, United States

Corona Regional Medical Center, Corona, California, United States

City of Hope Comprehensive Cancer Center, Duarte, California, United States

Scripps Memorial Hospitals-Stevens Cancer Center - Encinitas, Encinitas, California, United States

North Bay Cancer Center, Fairfield, California, United States

Kaiser Permanente Medical Center - Fontana, Fontana, California, United States

Crosson Cancer Center at St. Jude Medical Center, Fullerton, California, United States

Glendale Memorial Hospital Comprehensive Cancer Center, Glendale, California, United States

Oncology/Hematology Associates, Granada Hills, California, United States

Marin General Hospital Cancer Institute, Greenbrae, California, United States

Kaiser Permanente Medical Center - Harbor City, Harbor City, California, United States

Hemet Valley Medical Center, Hemet, California, United States

Rebecca and John Moores UCSD Cancer Center, La Jolla, California, United States

Valley Tumor Medical Group, Lancaster, California, United States

Loma Linda University Cancer Institute at Loma Linda University Medical Center, Loma Linda, California, United States

Todd Cancer Institute at Long Beach Memorial Medical Center, Long Beach, California, United States

Pacific Shores Medical Group Comprehensive Hematology-Oncology Services - Long Beach, Long Beach, California, United States

Kaiser Permanente Medical Center - Los Angeles, Los Angeles, California, United States

USC/Norris Comprehensive Cancer Center and Hospital, Los Angeles, California, United States

Cecilia Gonzalez De La Hoya Cancer Center at White Memorial Medical Center, Los Angeles, California, United States

Kaiser Foundation Hospital - West Los Angeles, Los Angeles, California, United States

St. Vincent Medical Center - Los Angeles, Los Angeles, California, United States

Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California, United States

Mission Cancer Center at Mission Hospital, Mission Viejo, California, United States

Sutter Gould Medical Foundation, Modesto, California, United States

Leavey Cancer Center at Northridge Hospital Medical Center, Northridge, California, United States

Breast Health Center, Oceanside, California, United States

St. Joseph Hospital Regional Cancer Center - Orange, Orange, California, United States

Chao Family Comprehensive Cancer Center at University of California Irvine Cancer Center, Orange, California, United States

Ventura Hematology - Oncology Specialists - Oxnard, Oxnard, California, United States

Comprehensive Cancer Centers of the Desert, Palm Springs, California, United States

Palo Alto Medical Foundation, Palo Alto, California, United States

Kaiser Permanente Medical Group, Panorama City, California, United States

Huntington Cancer Center at Huntington Hospital, Pasadena, California, United States

Wilshire Oncology Medical Group, Incorporated - Pomona, Pomona, California, United States

North Valley Breast Clinic, Redding, California, United States

Kaiser Permanente Medical Center - Riverside, Riverside, California, United States

Sutter Roseville Medical Center, Roseville, California, United States

Sutter Breast Cancer Group, Sacramento, California, United States

Kaiser Permanente Medical Center/Kaiser Foundation Hospital - San Diego, San Diego, California, United States

Naval Medical Center - San Diego, San Diego, California, United States

California Pacific Medical Center - California Campus, San Francisco, California, United States

UCSF Comprehensive Cancer Center, San Francisco, California, United States

Cancer Center of Santa Barbara, Santa Barbara, California, United States

CCOP - Santa Rosa Memorial Hospital, Santa Rosa, California, United States

Stanford Cancer Center at Stanford University Medical Center, Stanford, California, United States

Torrance Memorial Medical Center, Torrance, California, United States

Santa Clarita Valley Cancer Center - UCLA, Valencia, California, United States

Kaiser Permanente Medical Center - Vallejo, Vallejo, California, United States

Kaiser Permanente Medical Cener - Woodland Hills, Woodland Hills, California, United States

Penrose Cancer Center, Colorado Springs, Colorado, United States

CCOP - Colorado Cancer Research Program, Incorporated, Denver, Colorado, United States

Poudre Valley Hospital, Fort Collins, Colorado, United States

St. Mary-Corwin Regional Medical Center, Pueblo, Colorado, United States

University of Connecticut Comprehensive Cancer Center at University of Connecticut Health Center, Farmington, Connecticut, United States

Hartford Hospital, Hartford, Connecticut, United States

St. Francis Hospital and Medical Center, Hartford, Connecticut, United States

Manchester Memorial Hospital, Manchester, Connecticut, United States

Midstate Medical Center, Meriden, Connecticut, United States

New Britain General Hospital, New Britain, Connecticut, United States

Hospital of St. Raphael, New Haven, Connecticut, United States

Yale Comprehensive Cancer Center, New Haven, Connecticut, United States

Lawrence and Memorial Hospital, New London, Connecticut, United States

Eastern Connecticut Hematology and Oncology Associates, Norwich,, Connecticut, United States

Hematology Oncology, P.C., Stamford, Connecticut, United States

Northwestern Connecticut Oncology-Hematology Associates, Torrington, Connecticut, United States

Windham Community Memorial Hospital, Williamantic, Connecticut, United States

Beebe Medical Center, Lewes, Delaware, United States

Nanticoke Memorial Hospital, Seaford, Delaware, United States

CCOP - Christiana Care Health Services, Wilmington, Delaware, United States

Lombardi Cancer Center at Georgetown University Medical Center, Washington, District of Columbia, United States

Washington Hospital Center, Washington, District of Columbia, United States

Providence Hospital, Washington, District of Columbia, United States

JFK Medical Center, Atlantis, Florida, United States

St. Vincent's Medical Center, Jacksonville, Florida, United States

Baptist Regional Cancer Institute - Jacksonville, Jacksonville, Florida, United States

Mayo Clinic - Jacksonville, Jacksonville, Florida, United States

Ella Milbank Foshay Cancer Center at Jupiter Medical Center, Jupiter, Florida, United States

Watson Clinic, Lakeland, Florida, United States

Lakeland Regional Cancer Center at Lakeland Regional Medical Center, Lakeland, Florida, United States

CCOP - Mount Sinai Medical Center, Miami Beach, Florida, United States

University of Miami Sylvester Cancer Center, Miami, Florida, United States

Florida Hospital Medical Center, Orlando, Florida, United States

MD Anderson Cancer Center Orlando, Orlando, Florida, United States

West Florida Regional Medical Center, Pensacola, Florida, United States

Cancer Research Network Inc., Plantation, Florida, United States

Clinical Research Center of South Florida, Stuart, Florida, United States

H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States

Palm Beach Cancer Institute, West Palm Beach, Florida, United States

CCOP - Atlanta Regional, Atlanta, Georgia, United States

Medical College of Georgia, Augusta, Georgia, United States

Curtis & Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center, Savannah, Georgia, United States

Cancer Care and Research Pavilion at St. Joseph's/Candler, Savannah, Georgia, United States

MBCCOP - Hawaii, Honolulu, Hawaii, United States

North Idaho Cancer Center, Coeur d'Alene, Idaho, United States

Northwest Community Hospital, Arlington Heights, Illinois, United States

Rush Copley Medical Center, Aurora, Illinois, United States

Robert H. Lurie Comprehensive Cancer Center at Northwestern University, Chicago, Illinois, United States

Northwestern Memorial Hospital, Chicago, Illinois, United States

MBCCOP - University of Illinois at Chicago, Chicago, Illinois, United States

John H. Stroger, Jr. Hospital of Cook County, Chicago, Illinois, United States

Rush Cancer Institute at Rush University Medical Center, Chicago, Illinois, United States

Resurrection Medical Center, Chicago, Illinois, United States

Our Lady of the Resurrection Medical Center, Chicago, Illinois, United States

University of Chicago Cancer Research Center, Chicago, Illinois, United States

Creticos Cancer Center at Advocate Illinois Masonic Medical Center, Chicago, Illinois, United States

CCOP - Central Illinois, Decatur, Illinois, United States

Sherman Hospital, Elgin, Illinois, United States

CCOP - Evanston, Evanston, Illinois, United States

St. Francis Hospital, Evanston, Illinois, United States

Ingalls Memorial Hospital, Harvey, Illinois, United States

Advocate South Suburban Hospital, Hazel Crest, Illinois, United States

Evanston Northwestern Health Care - Highland Park Hospital, Highland Park, Illinois, United States

Hinsdale Hematology Oncology Associates, Hinsdale, Illinois, United States

Joliet Oncology Hematology Associates, Limited - Joliet, Joliet, Illinois, United States

Cardinal Bernardin Cancer Center at Loyola University Medical Center, Maywood, Illinois, United States

Edward Hospital Cancer Center, Naperville, Illinois, United States

Mid-Illinois Hematology-Oncology Associates, Normal, Illinois, United States

Advocate Christ Medical Center, Oak Lawn, Illinois, United States

Saint James Hospital and Health Centers Comprehensive Cancer Institute, Olympia Fields, Illinois, United States

Lutheran General Cancer Care Center, Park Ridge, Illinois, United States

CCOP - Illinois Oncology Research Association, Peoria, Illinois, United States

Trinity Medical Center - West, Rock Island, Illinois, United States

Rockford Clinic, Rockford, Illinois, United States

Swedish-American Regional Cancer Center, Rockford, Illinois, United States

Saint Anthony Medical Center, Rockford, Illinois, United States

Edward H. Kaplan MD and Associates, Skokie, Illinois, United States

St. John's Hospital, Springfield, Illinois, United States

Memorial Medical Center, Springfield, Illinois, United States

CCOP - Carle Cancer Center, Urbana, Illinois, United States

Center for Cancer Care at Goshen Health System, Goshen, Indiana, United States

Indiana Community Cancer Care, Incorporated, Indianapolis, Indiana, United States

Methodist Cancer Center at Methodist Hospital, Indianapolis, Indiana, United States

Indiana Regional Cancer Center, Indianapolis, Indiana, United States

St. Vincent Hospital and Health Care Center, Indianapolis, Indiana, United States

Oncology Institute of Greater Lafayette, Lafayette, Indiana, United States

Saint Anthony Memorial Health Centers, Michigan City, Indiana, United States

Ball Memorial Hospital Cancer Center, Muncie, Indiana, United States

Community Hospital, Munster, Indiana, United States

CCOP - Northern Indiana CR Consortium, South Bend, Indiana, United States

McFarland Clinic, P.C., Ames, Iowa, United States

CCOP - Cedar Rapids Oncology Project, Cedar Rapids, Iowa, United States

Medical Associates, Clinton, Iowa, United States

Jennie Edmundson Memorial Hospital, Council Bluffs, Iowa, United States

Genesis Regional Cancer Center at Genesis Medical Center, Davenport, Iowa, United States

CCOP - Iowa Oncology Research Association, Des Moines, Iowa, United States

Wendt Regional Cancer Center of Finley Hospital, Dubuque, Iowa, United States

Holden Comprehensive Cancer Center at University of Iowa, Iowa City, Iowa, United States

Mercy Cancer Center at Mercy Medical Center - North Iowa, Mason City, Iowa, United States

Ottumwa Regional Health Center, Ottumwa, Iowa, United States

Siouxland Hematology-Oncology, Sioux City, Iowa, United States

Cedar Valley Medical Specialists, P.C., Waterloo, Iowa, United States

Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center, Kansas City, Kansas, United States

CCOP - Wichita, Wichita, Kansas, United States

King's Daughters Medical Center, Ashland, Kentucky, United States

St. Elizabeth Medical Center, Edgewood, Kentucky, United States

HCA Kings Daughters Memorial Hospital, Frankfort, Kentucky, United States

Central Baptist Hospital, Lexington, Kentucky, United States

Markey Cancer Center at University of Kentucky Chandler Medical Center, Lexington, Kentucky, United States

Norton Healthcare Cancer Center, Louisville, Kentucky, United States

James Graham Brown Cancer Center at University of Louisville, Louisville, Kentucky, United States

Baptist Hospital East - Louisville, Louisville, Kentucky, United States

Ochsner Clinic of Baton Rouge, Baton Rouge, Louisiana, United States

Baton Rouge General Medical Center, Baton Rouge, Louisiana, United States

Cancer Care Specialists, Houma, Louisiana, United States

MBCCOP - LSU Health Sciences Center, New Orleans, Louisiana, United States

Tulane Cancer Center at Tulane University Hospital and Clinic, New Orleans, Louisiana, United States

CCOP - Ochsner, New Orleans, Louisiana, United States

Cancer Treatment Center at Christus Schumpert St. Mary Place, Shreveport, Louisiana, United States

Eastern Maine Medical Center, Bangor, Maine, United States

Goodall Hospital, Sanford, Maine, United States

Maine Center for Cancer Medicine and Blood Disorders - Scarborough, Scarborough, Maine, United States

Anne Arundel Medical Center, Annapolis, Maryland, United States

Greenebaum Cancer Center at University of Maryland Medical Center, Baltimore, Maryland, United States

Greater Baltimore Medical Center and Cancer Center, Baltimore, Maryland, United States

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States

Franklin Square Hospital Center, Baltimore, Maryland, United States

Suburban Hospital, Bethesda, Maryland, United States

Frederick Memorial Hospital Regional Cancer Therapy Center, Frederick, Maryland, United States

Massachusetts General Hospital Cancer Center, Boston, Massachusetts, United States

Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute, Boston, Massachusetts, United States

Cancer Research Center at Boston Medical Center, Boston, Massachusetts, United States

Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States

Harvard Vanguard Medical Associates - Kenmore, Boston, Massachusetts, United States

Lahey Clinic Medical Center - Burlington, Burlington, Massachusetts, United States

Saint Anne's Hospital, Fall River, Massachusetts, United States

Caritas Norwood Hospital, Norfolk, Massachusetts, United States

NSMC Cancer Center, Peabody, Massachusetts, United States

Berkshire Physicians and Surgeons, P.C., Pittsfield, Massachusetts, United States

Jordan Hospital Club Cancer Center, Plymouth, Massachusetts, United States

Baystate Regional Cancer Program at Baystate Medical Center, Springfield, Massachusetts, United States

University of Massachusetts Memorial Medical Center - University Campus, Worcester, Massachusetts, United States

Hickman Cancer Center at Bixby Medical Center, Adrian, Michigan, United States

CCOP - Michigan Cancer Research Consortium, Ann Arbor, Michigan, United States

University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, United States

Battle Creek Health System, Battle Creek, Michigan, United States

Bay Diagnostic Center for Women, Bay City, Michigan, United States

Community Health Center of Branch County, Coldwater, Michigan, United States

Oakwood Hospital and Medical Center, Dearborn, Michigan, United States

Barbara Ann Karmanos Cancer Institute, Detroit, Michigan, United States

Josephine Ford Cancer Center at Henry Ford Hospital, Detroit, Michigan, United States

St. John Hospital and Medical Center, Detroit, Michigan, United States

Hurley Medical Center, Flint, Michigan, United States

Flint Hematology Oncology, Flint, Michigan, United States

Genesys Regional Medical Center, Grand Blanc, Michigan, United States

CCOP - Grand Rapids, Grand Rapids, Michigan, United States

Holland Community Hospital, Holland, Michigan, United States

Center for Hematology/Oncology, Jackson, Michigan, United States

CCOP - Kalamazoo, Kalamazoo, Michigan, United States

Michigan State University Department of Surgery, Lansing, Michigan, United States

Lapeer Regional Hospital, Lapeer, Michigan, United States

Marquette General Hospital, Marquette, Michigan, United States

Mercy Memorial Hospital, Corporation, Monroe, Michigan, United States

Community Cancer Care Specialist, Mount Clemens, Michigan, United States

Memorial Healthcare, Owosso, Michigan, United States

Blue Water Oncology PC, Port Huron, Port Huron, Michigan, United States

CCOP - Beaumont, Royal Oak, Michigan, United States

Saint Mary's Seton Cancer Institute, Saginaw, Michigan, United States

Providence Cancer Institute at Providence Hospital, Southfield, Michigan, United States

Munson Medical Center, Traverse City, Michigan, United States

St. John Macomb Hospital, Warren, Michigan, United States

CCOP - Duluth, Duluth, Minnesota, United States

St. Luke's Medical Clinic, Duluth, Minnesota, United States

Minnesota Cooperative Group Program, Minneapolis, Minnesota, United States

Hennepin County Medical Center - Minneapolis, Minneapolis, Minnesota, United States

University of Minnesota, Minneapolis, Minnesota, United States

Mayo Clinic Cancer Center, Rochester, Minnesota, United States

CCOP - Metro-Minnesota, Saint Louis Park, Minnesota, United States

Rice Memorial Hospital, Willmar, Minnesota, United States

Coast Oncology/Hematology, P.L.L.C., Biloxi, Mississippi, United States

Mid Delta Family Practice, Cleveland, Mississippi, United States

Hattiesburg Clinic, P.A., Hattiesburg, Mississippi, United States

Jackson Oncology Associates, PLLC, Jackson, Mississippi, United States

Keesler Medical Center - Keesler Air Force Base, Keesler AFB, Mississippi, United States

North Mississippi Hematology and Oncology Associates, Limited, Tupelo, Mississippi, United States

Saint Luke's Hospital, Chesterfield, Missouri, United States

Ellis Fischel Cancer Center at University of Missouri - Columbia, Columbia, Missouri, United States

Freeman Cancer Institute at Freeman Health System, Joplin, Missouri, United States

St. John's Regional Medical Center, Joplin, Missouri, United States

CCOP - Kansas City, Kansas City, Missouri, United States

Phelps County Regional Medical Center, Rolla, Missouri, United States

Midwest Hematology Oncology Group, Inc., Saint Louis, Missouri, United States

Siteman Cancer Center, Saint Louis, Missouri, United States

Missouri Baptist Cancer Center, Saint Louis, Missouri, United States

CCOP - St. Louis-Cape Girardeau, Saint Louis, Missouri, United States

St. John's Regional Health Center, Springfield, Missouri, United States

CCOP - Cancer Research for the Ozarks, Springfield, Missouri, United States

Missouri Cancer Care, P.C. - St. Charles, St. Charles, Missouri, United States

Ozarks Medical Center, West Plains, Missouri, United States

CCOP - Montana Cancer Consortium, Billings, Montana, United States

Montana Cancer Institute - Benefis Healthcare, Great Falls, Montana, United States

Kalispell Regional Medical Center, Kalispell, Montana, United States

Saint Francis Medical Center, Grand Island, Nebraska, United States

Cancer Center at the Good Samaritan Health Systems, Kearney, Nebraska, United States

Cancer Resource Center - Lincoln, Lincoln, Nebraska, United States

Methodist Hospital Cancer Center at Nebraska Methodist Hospital - Omaha, Omaha, Nebraska, United States

Alegent Health - Immanuel Medical Center, Omaha, Nebraska, United States

Bergan Mercy Medical Center, Omaha, Nebraska, United States

Creighton University Medical Center, Omaha, Nebraska, United States

CCOP - Southern Nevada Cancer Research Foundation, Las Vegas, Nevada, United States

New Hampshire Oncology-Hematology, PA - Hooksett, Hooksett, New Hampshire, United States

Southern New Hampshire Medical Center, Nashua, New Hampshire, United States

Cooper Cancer Institute, Camden, New Jersey, United States

Englewood Hospital and Medical Center, Englewood, New Jersey, United States

Hunterdon Regional Cancer Center, Flemington, New Jersey, United States

CCOP - Northern New Jersey, Hackensack, New Jersey, United States

St. Barnabas Medical Center, Livingston, New Jersey, United States

Monmouth Medical Center, Long Branch, New Jersey, United States

South Jersey Regional Cancer Center, Millville, New Jersey, United States

Fox Chase Virtua Health Cancer Program at Virtua Memorial Hospital, Mount Holly, New Jersey, United States

Cancer Institute of New Jersey, New Brunswick, New Jersey, United States

Newark Beth Israel Medical Center, Newark, New Jersey, United States

Warren Hospital, Phillipsburg, New Jersey, United States

Atlantic City Medical Center, Pomona, New Jersey, United States

Booker Cancer Center at Riverview Medical Center, Red Bank, New Jersey, United States

Valley Hospital, Ridgewood, New Jersey, United States

Somerset Medical Center, Somerville, New Jersey, United States

Community Medical Center, Toms River, New Jersey, United States

Capital Health System at Mercer, Trenton, New Jersey, United States

Underwood Memorial Hospital, Woodbury, New Jersey, United States

Hematology-Oncology Associates, PC, Albuquerque, New Mexico, United States

Lovelace Medical Center at Lovelace Sandia Health System, Albuquerque, New Mexico, United States

New Mexico Oncology-Hematology Consultants, Limited, Albuquerque, New Mexico, United States

University of New Mexico Cancer Research and Treatment Center, Albuquerque, New Mexico, United States

New Mexico Cancer Care Associates, Santa Fe, New Mexico, United States

New York Oncology Hematology, P.C. - Albany Regional Cancer Center, Albany, New York, United States

Albert Einstein Clinical Cancer Center, Bronx, New York, United States

Comprehensive Cancer Center at Our Lady of Mercy Medical Center, Bronx, New York, United States

Roswell Park Cancer Institute, Buffalo, New York, United States

Louis Busch Hager Cancer Center at Mary Imogene Bassett Hospital, Cooperstown, New York, United States

Charles R. Wood Foundation Cancer Center at Glens Falls Hospital, Glens Falls, New York, United States

Queens Cancer Center of Queens Hospital, Jamaica, New York, United States

New York Oncology Hematology, P.C. - Latham, Latham, New York, United States

CCOP - North Shore University Hospital, Manhasset, New York, United States

Saint Vincent Catholic Medical Center of New York, New York, New York, United States

NYU School of Medicine's Kaplan Comprehensive Cancer Center, New York, New York, United States

Memorial Sloan-Kettering Cancer Center, New York, New York, United States

Herbert Irving Comprehensive Cancer Center at Columbia University, New York, New York, United States

St. Francis Hospital and Health Centers, Poughkeepsie, New York, United States

Vassar Brothers Medical Center, Poughkeepsie, New York, United States

Genesee Surgical Associates, Rochester, New York, United States

Gynecologic Oncology Associates, Rochester, New York, United States

James P. Wilmot Cancer Center at University of Rochester Medical Center, Rochester, New York, United States

University Hospital - Stony Brook, Stony Brook, New York, United States

University Hospital at State University of New York - Upstate Medical University, Syracuse, New York, United States

CCOP - Syracuse Hematology-Oncology Associates of Central New York, P.C., Syracuse, New York, United States

Mission Hospitals, Asheville, North Carolina, United States

Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill, Chapel Hill, North Carolina, United States

Blumenthal Cancer Center at Carolinas Medical Center, Charlotte, North Carolina, United States

Presbyterian Healthcare, Charlotte, North Carolina, United States

Duke Comprehensive Cancer Center, Durham, North Carolina, United States

Cape Fear Valley Health System, Fayetteville, North Carolina, United States

Gaston Hematology and Oncology, Gastonia, North Carolina, United States

Southeastern Medical Oncology Center, Goldsboro, North Carolina, United States

Moses Cone Regional Cancer Center at Wesley Long Community Hospital, Greensboro, North Carolina, United States

Leo W. Jenkins Cancer Center of University Health Systems of Eastern Carolina, Greenville, North Carolina, United States

Pardee Memorial Hospital, Hendersonville, North Carolina, United States

Cornerstone Surgery, High Point, North Carolina, United States

Raleigh Hematology/Oncology Associates, P.A. - Rex Cancer Center, Raleigh, North Carolina, United States

Cancer Center at Iredell Memorial Hospital, Statesville, North Carolina, United States

New Hanover Regional Medical Center, Wilmington, North Carolina, United States

Forsyth Medical Center, Winston-Salem, North Carolina, United States

CCOP - Southeast Cancer Control Consortium, Winston-Salem, North Carolina, United States

Comprehensive Cancer Center at Wake Forest University, Winston-Salem, North Carolina, United States

Quain & Ramstad Clinic, Bismarck, North Dakota, United States

CCOP - Merit Care Hospital, Fargo, North Dakota, United States

Akron General Medical Center, Akron, Ohio, United States

Mercy Medical Center, Canton, Ohio, United States

Aultman Hospital Cancer Center at Aultman Health Foundation, Canton, Ohio, United States

Cancer Center at Christ Hospital, Cincinnati, Ohio, United States

Bethesda North Hospital, Cincinnati, Ohio, United States

Charles M. Barrett Cancer Center at University Hospital, Cincinnati, Ohio, United States

Ireland Cancer Center, Cleveland, Ohio, United States

Fairview Hospital, Cleveland, Ohio, United States

Kaiser Permanente, Cleveland, Ohio, United States

Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio, United States

CCOP - Columbus, Columbus, Ohio, United States

Arthur G. James Cancer Hospital - Ohio State University, Columbus, Ohio, United States

Blanchard Valley Medical Associates, Findlay, Ohio, United States

Fremont Memorial Hospital, Fremont, Ohio, United States

Cleveland Clinic Cancer Center, Independence, Ohio, United States

CCOP - Dayton, Kettering, Ohio, United States

Lima Memorial Hospital, Lima, Ohio, United States

St. Luke's Hospital, Maumee, Ohio, United States

Parma Community General Hospital, Parma, Ohio, United States

Firelands Regional Medical Center, Sandusky, Ohio, United States

Flower Hospital - ProMedica Health System, Sylvania, Ohio, United States

Toledo Hospital, Toledo, Ohio, United States

St. Vincent Mercy Medical Center, Toledo, Ohio, United States

Medical College of Ohio Cancer Institute, Toledo, Ohio, United States

St. Charles Hospital, Toledo, Ohio, United States

CCOP - Toledo Community Hospital, Toledo, Ohio, United States

Toledo Clinic, Incorporated, Toledo, Ohio, United States

Cleveland Clinic Health System STAR BCPT, Warrensville Heights, Ohio, United States

Fulton County Health Center, Wauseon, Ohio, United States

Muskogee Regional Medical Center, Muskogee, Oklahoma, United States

Frank C. Love Cancer Institute at St. Anthony Hospital, Oklahoma City, Oklahoma, United States

Central Oklahoma Cancer Center at INTEGRIS Southwest Medical Center, Oklahoma City, Oklahoma, United States

Mercy Health Center, Oklahoma City, Oklahoma, United States

Oklahoma University Medical Center at University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States

St. John Health System, Tulsa, Oklahoma, United States

CCOP - Oklahoma, Tulsa, Oklahoma, United States

St. Charles Medical Center, Bend, Oregon, United States

Cancer Institute at Oregon Health and Science University, Portland, Oregon, United States

CCOP - Columbia River Oncology Program, Portland, Oregon, United States

Kaiser Permanente Center for Health Research, Portland, Oregon, United States

Abington Memorial Hospital, Abington, Pennsylvania, United States

Sacred Heart Hospital, Allentown, Pennsylvania, United States

John and Dorothy Morgan Cancer Center at Lehigh Valley Hospital, Allentown, Pennsylvania, United States

Bon Secours-Holy Family Health System, Altoona, Pennsylvania, United States

St. Luke's Hospital Cancer Center, Bethlehem, Pennsylvania, United States

Bryn Mawr Hospital, Bryn Mawr, Pennsylvania, United States

Geisinger Medical Center, Danville, Pennsylvania, United States

Mercy Fitzgerald Hospital, Darby, Pennsylvania, United States

Doylestown Hospital, Doylestown, Pennsylvania, United States

Delaware County Memorial Hospital, Drexel Hill, Pennsylvania, United States

Easton Hospital, Easton, Pennsylvania, United States

Ephrata Community Hopital, Ephrata, Pennsylvania, United States

Regional Cancer Center - Erie, Erie, Pennsylvania, United States

Pinnacle Health Regional Cancer Center at Pinnacle Health System, Harrisburg, Pennsylvania, United States

Mercy Community Hospital, Havertown, Pennsylvania, United States

Penn State Cancer Institute at Milton S. Hershey Medical Center, Hershey, Pennsylvania, United States

Lancaster General Hospital, Lancaster, Pennsylvania, United States

Saint Mary Regional Cancer Center, Langhorne, Pennsylvania, United States

Riddle Memorial Hospital, Media, Pennsylvania, United States

Cancer Center at Paoli Memorial Hospital, Paoli, Pennsylvania, United States

Abramson Cancer Center at University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, United States

Kimmel Cancer Center at Thomas Jefferson University - Philadelphia, Philadelphia, Pennsylvania, United States

Pennsylvania Oncology Hematology Associates, Philadelphia, Pennsylvania, United States

Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States

Frankford Hospital, Philadelphia, Pennsylvania, United States

Chestnut Hill Healthcare, Philadelphia, Pennsylvania, United States

Fox Chase - Temple Cancer Center, Philadelphia, Pennsylvania, United States

Albert Einstein Cancer Center, Philadelphia, Pennsylvania, United States

Mercy Hospital of Philadelphia, Philadelphia, Pennsylvania, United States

Allegheny General Hospital, Pittsburgh, Pennsylvania, United States

Hillman Cancer Center at University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States

Pottstown Memorial Regional Cancer Center, Pottstown, Pennsylvania, United States

Reading Hospital and Medical Center, Reading, Pennsylvania, United States

Grand View Hospital, Sellersville, Pennsylvania, United States

Crozer-Chester Medical Center, Upland, Pennsylvania, United States

Chester County Hospital, West Chester, Pennsylvania, United States

Lankenau Cancer Center at Lankenau Hospital, Wynnewood, Pennsylvania, United States

Wellspan Health - York Cancer Center, York, Pennsylvania, United States

Rhode Island Hospital, Providence, Rhode Island, United States

AnMed Health, Anderson, South Carolina, United States

Roper St. Francis Healthcare - Roper Hospital, Charleston, South Carolina, United States

Hollings Cancer Center at Medical University of South Carolina, Charleston, South Carolina, United States

Palmetto Richland Memorial Hospital, Columbia, South Carolina, United States

McLeod Regional Medical Center, Florence, South Carolina, United States

Cancer Centers of the Carolinas - Eastside, Greenville, South Carolina, United States

CCOP - Upstate Carolina, Spartanburg, South Carolina, United States

Rapid City Regional Hospital, Rapid City, South Dakota, United States

CCOP - Sioux Community Cancer Consortium, Sioux Falls, South Dakota, United States

Wellmont Holston Valley Hospital and Medical Center, Kingsport, Tennessee, United States

Thompson Cancer Survival Center, Knoxville, Tennessee, United States

U.T. Cancer Institute at University of Tennessee Medical Center, Knoxville, Tennessee, United States

Baptist Cancer Institute - Memphis at Baptist Memorial Hospital - Memphis, Memphis, Tennessee, United States

MBCCOP - Meharry Medical College - Nashville, Nashville, Tennessee, United States

Vanderbilt-Ingram Cancer Center at Vanderbilt Medical Center, Nashville, Tennessee, United States

Hendrick Cancer Center, Abilene, Texas, United States

Harrington Cancer Center, Amarillo, Texas, United States

Julie and Ben Rogers Cancer Center, Beaumont, Texas, United States

Presbyterian Hospital of Dallas, Dallas, Texas, United States

Simmons Cancer Center at University of Texas Southwestern Medical Center - Dallas, Dallas, Texas, United States

Charles A. Sammons Cancer Center, Dallas, Texas, United States

Methodist Dallas Medical Center, Dallas, Texas, United States

Providence Memorial Hospital, El Paso, Texas, United States

Harris Methodist Fort Worth, Fort Worth, Texas, United States

University of Texas - MD Anderson Cancer Center, Houston, Texas, United States

Baylor College of Medicine, Houston, Texas, United States

Texas Cancer Institute at St. Luke's Episcopal Hospital, Houston, Texas, United States

Baylor Medical Center at Garland, Irving, Texas, United States

Wilford Hall Medical Center, Lackland Air Force Base, Texas, United States

Sanchez Cancer Center, Laredo, Texas, United States

Joe Arrington Cancer Research and Treatment Center, Lubbock, Texas, United States

Southwest Cancer and Research Center at University Medical Center, Lubbock, Texas, United States

Memorial Health System of East Texas, Lufkin, Texas, United States

Baylor/Richardson Cancer Center, Richardson, Texas, United States

University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States

CCOP - Scott and White Hospital, Temple, Texas, United States

University of Texas Health Center at Tyler, Tyler, Texas, United States

Huntsman Cancer Institute, Salt Lake City, Utah, United States

Green Mountain Oncology Group, Bennington, Vermont, United States

Southwestern Vermont Regional Cancer Center, Bennington, Vermont, United States

Mountainview Medical, Berlin, Vermont, United States

Vermont Cancer Center at University of Vermont, Burlington, Vermont, United States

Community Cancer Center at Rutland Regional Medical Center, Rutland, Vermont, United States

Martha Jefferson Hospital, Charlottesville, Virginia, United States

Cancer Center of the Piedmont, Inc., Danville, Virginia, United States

Danville Hematology and Oncology, Incorporated, Danville, Virginia, United States

Virginia Oncology Associates - Newport News, Newport News, Virginia, United States

Henrico Doctors' Hospital - Parham Campus, Richmond, Virginia, United States

MBCCOP - Massey Cancer Center, Richmond, Virginia, United States

Oncology and Hematology Associates of Southwest Virginia, Inc., Roanoke, Virginia, United States

St. Joseph Hospital Community Cancer Center, Bellingham, Washington, United States

Olympic Hematology and Oncology, Bremerton, Washington, United States

Flynn Cancer Center at Providence Everett Medical Center - Pacific Campus, Everett, Washington, United States

CCOP - Virginia Mason Research Center, Seattle, Washington, United States

Swedish Cancer Institute at Swedish Medical Center - First Hill Campus, Seattle, Washington, United States

Fred Hutchinson Cancer Research Center, Seattle, Washington, United States

Cancer Care Northwest - Spokane North, Spokane, Washington, United States

Rockwood Clinic P.S., Spokane, Washington, United States

CCOP - Northwest, Tacoma, Washington, United States

Yakima Regional Cancer Care Center, Yakima, Washington, United States

David Lee Cancer Center at Charleston Area Medical Center, Charleston, West Virginia, United States

Camden-Clark Memorial Hospital, Parkersburg, West Virginia, United States

Gundersen Lutheran Cancer Center at Gundersen Lutheran Medical Center, La Crosse, Wisconsin, United States

University of Wisconsin Comprehensive Cancer Center, Madison, Wisconsin, United States

CCOP - Marshfield Clinic Research Foundation, Marshfield, Wisconsin, United States

Aurora Sinai Medical Center, Milwaukee, Wisconsin, United States

Oncology Alliance, S.C., Milwaukee, Wisconsin, United States

Medical College of Wisconsin Cancer Center, Milwaukee, Wisconsin, United States

Waukesha Memorial Hospital Regional Cancer Center, Waukesha, Wisconsin, United States

UW Cancer Center Wausau Hospital, Wausau, Wisconsin, United States

Tom Baker Cancer Center - Calgary, Calgary, Alberta, Canada

Cross Cancer Institute, Edmonton, Alberta, Canada

University Hospital - U.B.C. Site, Vancouver, British Columbia, Canada

CancerCare Manitoba, Winnipeg, Manitoba, Canada

Familial Oncology Program, Kingston, Ontario, Canada

Credit Valley Hospital, Mississauga, Ontario, Canada

North York General Hospital, Ontario, North York, Ontario, Canada

Ottawa Regional Cancer Centre, Ottawa, Ontario, Canada

Northwestern Ontario Regional Cancer Care, Thunder Bay, Ontario, Canada

Toronto Sunnybrook Regional Cancer Centre, Toronto, Ontario, Canada

St. Michael's Hospital - Toronto, Toronto, Ontario, Canada

Toronto General Hospital, Toronto, Ontario, Canada

Women's College Ambulatory Care Center, Sunnybrook and Women's College Health Science Center, Toronto, Ontario, Canada

CHUS-Hopital Fleurimont, Fleurimont, Quebec, Canada

Hopital Charles Lemoyne, Greenfield Park, Quebec, Canada

Centre Hospitalier de l'Universite de Montreal, Montreal, Quebec, Canada

Royal Victoria Hospital - Montreal, Montreal, Quebec, Canada

Montreal General Hospital, Montreal, Quebec, Canada

Ville Marie Breast Center, Montreal, Quebec, Canada

Jewish General Hospital - Montreal, Montreal, Quebec, Canada

Hopital du Saint-Sacrement, Quebec, Quebec City, Quebec, Canada

Centre Universitaire de Sante de L'Estrie, Sherbrooke, Quebec, Canada

Saskatoon Cancer Centre, Saskatoon, Saskatchewan, Canada

MBCCOP - San Juan, San Juan, , Puerto Rico

Contact Details

Name: Norman Wolmark, MD

Affiliation: NSABP Foundation Inc

Role: STUDY_CHAIR

Useful links and downloads for this trial

Clinicaltrials.gov

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