Spots Global Cancer Trial Database for E7389 Versus Treatment of Physician's Choice in Patients With Locally Recurrent or Metastatic Breast Cancer
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Trial Identification
Brief Title: E7389 Versus Treatment of Physician's Choice in Patients With Locally Recurrent or Metastatic Breast Cancer
Official Title: The "EMBRACE" Trial: Eisai Metastatic Breast Cancer Study Assessing Physician's Choice Versus E7389. A Phase III Open-Label, Randomized, Parallel, Two-arm, Multi-center Study of E7389 Versus "Treatment of Physician's Choice" in Patients With Locally Recurrent, Metastatic Breast Cancer, Previously Treated With At Least Two and a Maximum of Five Prior Chemotherapy Regimens, Including an Anthracycline and a Taxane
Study ID: NCT00388726
Conditions
Study Description
Brief Summary: The purpose of this study is to compare Overall Survival (OS), Progression Free Survival (PFS), objective tumor response rate, duration of response, and safety in patients treated with E7389 versus the Treatment of Physician's Choice (TPC) in patients with locally recurrent or metastatic breast cancer.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Locations
US Oncology St. Vincent's Hospital - Bruno Cancer Center, Birmingham, Alabama, United States
Bellflower Satellite, Bellflower, California, United States
Research Center, Gilroy, California, United States
US Oncology, Denver, Colorado, United States
Florida Cancer Research Institute, Davie, Florida, United States
Innovative Medical Research of South Florida, Inc., Miami, Florida, United States
Peachtree Hematology/Oncology Consultants, PC, Atlanta, Georgia, United States
US Oncology, Niles, Illinois, United States
US Oncology, Indianapolis, Indiana, United States
University of Iowa Hospital and Clinic, Iowa City, Iowa, United States
Hematology Oncology Clinic, Baton Rouge, Louisiana, United States
Oncology Care Associates, P.L.L.C., Saint Joseph, Michigan, United States
US Oncology, Columbia, Missouri, United States
Montana Cancer Specialists, Missoula, Montana, United States
US Oncology, Las Vegas, Nevada, United States
US Oncology, Albany, New York, United States
North Shore Hematology/Oncology Associates, East Setauket, New York, United States
Weill Cornell Breast Cancer Center, New York, New York, United States
Carolina Hematology Oncology Associates, Charlotte, North Carolina, United States
US Oncology, Raleigh, North Carolina, United States
US Oncology, Eugene, Oregon, United States
St. Vincent Medical Center, Portland, Oregon, United States
US Oncology, Bedford, Texas, United States
US Oncology, Dallas, Texas, United States
US Oncology, Houston, Texas, United States
US Oncology, McAllen, Texas, United States
US Oncology, Midland, Texas, United States
US Oncology, Tyler, Texas, United States
US Oncology, Spokane, Washington, United States
Northwest Medical Specialists, Tacoma, Washington, United States
US Oncology, Vancouver, Washington, United States
US Oncology, Yakima, Washington, United States
Instituto Oncologico "Las Heras", Bahia Blanca, Buenos Aires, Argentina
Hospital Britanico, C.a.b.a, Buenos Aires, Argentina
Instituto FIDES especialidades Medicas, La Plata, Buenos Aires, Argentina
Breast Clinica de la Mama, La Plata, Buenos Aires, Argentina
CER Instituto Medico, Quilmes Oeste, Buenos Aires, Argentina
CITEM, Quilmes, Buenos Aires, Argentina
Instituto CAICI, Rosario, Pcia. Santa Fe, Argentina
Centro Medico San Roque, Tucuman, San Miguel De Tucuman, Argentina
Hosptial Interzonal General de Mar del Plata, Buenos Aires, , Argentina
Clinica Universitaria Privada Reina Fabiola, Cordoba, , Argentina
Sanatorio Frances, Cordoba, , Argentina
Instituto de Oncologia y Especialidades Medicas, Rosario Santa Fe, , Argentina
Clinica Especializada ISIS, Santa Fe, , Argentina
The Queen Elizabeth Hospital, Southport, Queensland, Australia
Servicio De Oncologia, Woodville South, South Australia, Australia
Maroondah Breast Clinic, Melbourne, , Australia
Mater Medical Centre, North Sydney, , Australia
Mount Hospital, Perth, , Australia
Royal Perth Hospital, Department of Medical Oncology, Perth, , Australia
Medizinische Universitatsklinik Graz, Graz Steiermark, , Austria
Salzburger Landeskliniken Universitatsklinik fur Innere medizin III, Salzburg, , Austria
Institut Jules Bordet, Brussels, , Belgium
Cliniques Universitaires Saint-Luc, Bruxelles, , Belgium
Centre Hospitalier Notre-Dame - Reine Fabiola, Charleroi, , Belgium
UZ Gent, Gent, , Belgium
AZ Groeninge, Campus Maria's Voorzienigheid, Kortrijk, , Belgium
Centro Regional Integrado de Oncologia-CRIO, Fortaleza, CE, Brazil
Centro de Pesquisas e Estudios do Centro Goiano, Giana, GO, Brazil
Hospital Erasto Gaertner, Curitiba, PA, Brazil
Instituto Nacional do Cancer-Unidade III (INCA III), Rio De Janiero, RJ, Brazil
CPO-Centro de Pesquisas em Oncologia, Porto Alegre, RS, Brazil
CEPHO-Centro de Estudos e Pesquisa de Hematologia e oncologia, Santo Andre, SP, Brazil
Santo Andre Diagnosticos e Tratamentos, Santo Andre, SP, Brazil
Clinica de Oncologia Medica, Sao Paulo, SP, Brazil
Hospital Amaral Carvalho, Vila Assis, SP, Brazil
The Ottawa Hospital Regional Cancer Center, Ottawa, Ontario, Canada
Sunnybrook Odette Cancer Centre, Toronto, Ontario, Canada
McGill University Health Centre, Department of Oncology, Gerald Bronfman Center, Montreal, Quebec, Canada
Clinical Hospital Osijek, Osijek, , Croatia
University Hospital Center Zagreb, Zagreb, , Croatia
University Hospital for Tumors Zagreb, Zagreb, , Croatia
Masaryk Memorial Cancer Institute, Brno, , Czechia
Hospital Jihlava, Jihlava, , Czechia
General Faculty Hospital Prague, Prague, , Czechia
Fakultni Thomayerova Nemocnice, Prague, , Czechia
Clinic of Radiotherapy and Oncology, Praha 10, , Czechia
Ustav radia ni onkologie 1. LF UK a FNB, Praha, , Czechia
Centre Paul Papin, Agners Cedex 01, , France
Hopital Jean Minjoz, Besancon, , France
Polyclinique Boredaux Nord Aquitaine, Bordeaux, , France
Centre Francois Baclesse Caen, Caen Cedex 05, , France
Centre Jean Perrin - CRLC, Clermont-Ferrand Cedex 01, , France
Centre Georges-Francois Lecierc, Dijon Cedex, , France
Hopital Edourad Herriot, Lyon, , France
Institut Curie, Paris, , France
Clinique Armoricaine de Radiologie, Saint Brieuc Cedex, , France
Hopital Bretonneau, Tours Cedex, , France
Semmelweis Medical University, III. Dep. of Internal Med., Budapest, , Hungary
Debrecen Medical University, Department of Oncology, Debrecen, , Hungary
University of Pecs, Pecs, , Hungary
Markusovszky Teaching Hospital, Dept. of Oncoradiology, Sec. Med. Oncology, Szombathely, , Hungary
Azienda Ospedaliera Careggi, Firenze (FI), , Italy
Ospedale San Martino, Genova, , Italy
Ospedale "Vito Fazzi" - Lecce, Lecce (LE), , Italy
Istituto Scientifico San Raffaele, Milano, , Italy
Ospedale San Filippo Neri, Roma, , Italy
Istituto Clinico Humanitas, Rozzano, , Italy
UO di Oncologia, Sora, , Italy
Akademickie Centrum Kliniczne Szpital Akademii Medycznej w, Gdansk, , Poland
Szpital Morski im PCK w Gdyni Gdynskie Centrum Onkologii, Gdynia, , Poland
Centrum Onkologii Instytut M. Sklodowskiej Curie w Warszawie Oddzial Gilwice, Gilwice, , Poland
Centrum Onkologii Instytut M Sklodowskiej Curie, Oddzial w Krakowie, Krakow, , Poland
Szpital Kiniczny Przemienienia Panskiego Uniwersyteu Medycznego im Karola Marcinkowskiego w Poznaniu, Poznan, , Poland
Zachodniopomorski e Centrum, Szczecin, , Poland
Centrum Onkologii Instytut im M. Sklodowskiej Curie w Warszawie, Warszawa, , Poland
Republic Clinical Oncology Dispensary, Izhervsk Udmurtia, , Russian Federation
Kazan State Medical University, Kazan, , Russian Federation
Krasnodar Territory Clinical Oncology Center, Krasnodar, , Russian Federation
Burdenko Main Military Hospital, Moscow, , Russian Federation
Nizhniy Novgorod City Oncology Center, Nizhny Novgorod, , Russian Federation
City Clinical Hospital #1, Novosibirisk, , Russian Federation
Republican Oncology Center, Petrozavodsk, , Russian Federation
State Institution of Healthcare Stavropol Region clinical Oncology dispensary, Pyatigorsk, , Russian Federation
St Petersburg City Oncology Center, St Petersburg, , Russian Federation
Pavlov Medical University, St. Petersburg, , Russian Federation
NN Petrov Research Institute of Oncology, St. Petersburg, , Russian Federation
Tomsk Regional Oncology Dispensary, Tomsk, , Russian Federation
GUZ YO Regional Clinical Oncology Hospital, Yaroslavl, , Russian Federation
Panorama Medical Centre, Panorama, Cape Town, South Africa
Eastern Cape Oncology Centre, GVI, St Georges Hospital, Port Elizabeth, Eastern Cape, South Africa
Sandton Oncology Centre, Johannesburg, , South Africa
Pretoria Academic Hospital, Pretoria, , South Africa
Hospital Vall d Hebron, Barcelona, , Spain
Hospital Mutua de Terrassa, Barcelona, , Spain
Hospital Universitario de Girona Dr. Josep Trueta, Gerona, , Spain
Complejo Hospitalario de Jaen, Jaen, , Spain
Hospital Unversitatio de Salamanca, Salamanca, , Spain
Hospital Universitario de Canarias, Santa Cruz de Tenerife, , Spain
Hospital General Virgen del Rocio, Sevilla, , Spain
Hospital Clinico de Zaragoza, Zanagoza, , Spain
Kantonsspital Aarau, Aarau, , Switzerland
Inselspital Bern, Bern Bern, , Switzerland
Kantonsspital Oncology Haematology, St. Gallen, , Switzerland
Spital Thun-Simmental AG, Thun, , Switzerland
Kantonsspital Winterhur, Winterhur, , Switzerland
Contact Details
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