Behaviors and Mental Disorders

All Conditions

Neoplasms

Skin and Connective Tissue Diseases

Anxiety Disorders

Breast Neoplasms

Depression

Depressive Disorder

Breast Diseases

Skin Diseases

Behavioral Symptoms

Mood Disorders

Mental Disorders

Psychotic Disorders

The group will receive clinical management treatment only each session.

Participants with breast cancer in the control group received standard medical care, but don't receive any other interventions.

The subjects will receive standardized CBT treatment regularly for 9 sessions(once per week in the first month and once half a month in the second and third months), and each session will last for about 60 minutes.The treatment includes three steps:Concept stage (the first and second sessions): establishment of therapeutic relationships with the subjects; Skills acquisition and repeat stage (the third session to the 8th session): clarification of sources of stress, patients' cognitive and behavioral response to stress. Application and complete price segment (the 9th session): return visit to test efficacy of psychological intervention.

Clinical management is a clear contrast method of psychological therapy, which is a half-structured interview and lasting for 20-25 minutes each session. Clinical management will be assigned to both experimental group and controlled group in the first stage of intervention.

Following are major elements:

Talk to the subjects to find their main problems; introduce knowledge and medication knowledge about cancer and depression; subjects reporting use of drugs for cancer and depression and a variety of signs and symptoms of the reaction. Encourage patients to adhere to drug treatment and to comply with this research program; The operation of CBT and clinical management should be conducted by the same person as far as possible.

Clinical Management

Jin C He, MD

The purpose of this study is to evaluate the efficacy of cognitive-behavioral therapy on depression and anxiety in breast cancer patients.

Comprehensive intervention on depression and anxiety in breast cancer patients is a 24-week, multicenter, randomized, blinded controlled clinical study, which uses cognitive-behavioral therapy. This study tries to evaluate the efficacy of sequential therapy on breast cancer patients' depression and its improvement on breast cancer patients' life quality, pain and sleeping.

Intervention Study of Depression in Breast Cancer Patients

Early Identification and Early Warning of Psychological Problems in Breast Cancer Patients, and Intervention Study Using Cognitive Behavioral Therapy on Depression in Breast Cancer Patients

1. The scale(HAMD-17) is used to assessed the depression symptoms of patients.
2. The scale range is 0-53.Higher value represents a worse outcome.
3. The scale was assessed at baseline,2 week,4 week,8 week,12 week,16 week,24 week

1. The scale(HAMA-14) is used to assessed the anxiety symptoms of patients.
2. The scale range is 0-56.Higher value represents a worse outcome.
3. The scale was assessed at baseline,2 week,4 week,8 week,12 week,16 week,24 week.

1. The scale is used to assess the pain intensity of patients.
2. The scale range of VAS is 0-10. Higher score indicates a higher intensity of pain.
3. The scale was assessed at baseline,4 week,8 week,12 week,24 week

1. The scale is used to assess the sleep quality of patients.
2. The scale range of AIS is 0-21. Higher score indicates worse sleep quality.
3. The scale was assessed at baseline,4 week,8 week,12 week,24 week

1. The scale is used to assess the life quality of patients.
2. The scale includes 5 subscales. The scores of each scale are summed to compute a total score.
3. The scale range is 0-144. Higher score indicates better life quality.
4. The scale was assessed at baseline,4 week,12 week,24 week.

Anhui Medical University

Central South University

Harbin Medical University

Second Affiliated Hospital, School of Medicine, Zhejiang University

Wuhan University

Wenzhou Medical University

Study Chair

The group will receive clinical management treatment only each session.

Clinical Management: Clinical management is a clear contrast method of psychological therapy, which is a half-structured interview and lasting for 20-25 minutes each session. Clinical management will be assigned to both experimental group and controlled group in the first stage of intervention.

Following are major elements:

Talk to the subjects to find their main problems; introduce knowledge and medication knowledge about cancer and depression; subjects reporting use of drugs for cancer and depression and a variety of signs and symptoms of the reaction. Encourage patients to adhere to drug treatment and to comply with this research program; The operation of CBT and clinical management should be conducted by the same person as far as possible.

Stage 1 Clinical Management

The experimental group will receive CBT each session.

CBT and clinical management: The subjects will receive standardized CBT treatment regularly for 9 sessions(once per week in the first month and once half a month in the second and third months), and each session will last for about 60 minutes.The treatment includes three steps:Concept stage (the first and second sessions): establishment of therapeutic relationships with the subjects; Skills acquisition and repeat stage (the third session to the 8th session): clarification of sources of stress, patients' cognitive and behavioral response to stress. Application and complete price segment (the 9th session): return visit to test efficacy of psychological intervention.

stage1 CBT

stage1 Control Group

The experimental group each session.

CBT: The subjects will receive standardized CBT treatment regularly for 9 sessions(once per week in the first month and once half a month in the second and third months), and each session will last for about 60 minutes.The treatment includes three steps:Concept stage (the first and second sessions): establishment of therapeutic relationships with the subjects; Skills acquisition and repeat stage (the third session to the 8th session): clarification of sources of stress, patients' cognitive and behavioral response to stress. Application and complete price segment (the 9th session): return visit to test efficacy of psychological intervention.

Total

Age, Continuous

Sex: Female, Male

Director of Clinical Trials

baseline

Stage 1 CBT

Stage 1 Control Group

Hamilton Depression Rating Scale (HAMD-17)

The experimental group will receive CBT each session.

CBT: The subjects will receive standardized CBT treatment regularly for 9 sessions(once per week in the first month and once half a month in the second and third months), and each session will last for about 60 minutes.The treatment includes three steps:Concept stage (the first and second sessions): establishment of therapeutic relationships with the subjects; Skills acquisition and repeat stage (the third session to the 8th session): clarification of sources of stress, patients' cognitive and behavioral response to stress. Application and complete price segment (the 9th session): return visit to test efficacy of psychological intervention.

Spots Global Cancer Trial Database for Intervention Study of Depression in Breast Cancer Patients

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