Spots Global Cancer Trial Database for Study of the Therapeutic Effect of Atorvastatin on the Clinical Outcomes in HER2 Negative Breast Cancer Patients"
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Trial Identification
Brief Title: Study of the Therapeutic Effect of Atorvastatin on the Clinical Outcomes in HER2 Negative Breast Cancer Patients"
Official Title: Study of the Therapeutic Effect of Atorvastatin on the Clinical Outcomes in HER2 Negative Breast Cancer Patients"
Study ID: NCT05103644
Conditions
Study Description
Brief Summary: Statins, a major class of drugs for treatment of hypercholesterolemia, are widely used due to a notable prevention of cardiovascular disease, and accumulating evidence proposes a promising role of statins in breast cancer
Detailed Description: Statin has lipid independent effects include inhibition of inflammatory responses, immunomodulatory actions, apoptotic and antiproliferative effects, which might contribute to the suggested anti-tumoral effects of these agents. The epidemiological evidence projecting statins as anticancer agents is variable, depending on the particular type of cancer in question as well as the class of statin used
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Locations
Beni-Suef university hospital, Banī Suwayf, , Egypt
Fayoum Oncology Center, Fayoum, , Egypt
Contact Details
Name: Ahmed Hassan shaaban, MD
Affiliation: Beni-Suef University
Role: STUDY_DIRECTOR
Name: Raghda RS Hussein, PHD
Affiliation: Beni-Suef University
Role: STUDY_DIRECTOR
Name: Reham shehab El-Nemr, MD
Affiliation: Fayoum University
Role: STUDY_DIRECTOR
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